Health / Medical Topics

    H19 wt Allele

    Human H19 wild-type allele is located in the vicinity of 11p15.5 and is approximately 6 kb in length. This allele, which encodes CDNA FLJ32212 fis, clone PLACE6003399, weakly similar to SPIDROIN 1 protein, is an imprinted gene that is only expressed from the maternal allele. The H19 gene plays a putative role in the inhibition of cell growth. This gene is associated with Beckwith-Wiedemann syndrome, embryonal neoplasms and nephroblastoma. (NCI Thesaurus)




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