| Health / Medical Topics |
Heparin
Pronunciation
Definition 1
A substance that slows the formation of blood clots. Heparin is made by the liver, lungs, and other tissues in the body and can also made in the laboratory. Heparin may be injected into muscle or blood to prevent or break up blood clots. It is a type of anticoagulant. (NCI Dictionary)
Definition 2
A sulfur-rich glycosaminoglycan with anticoagulant property. Heparin binds to antithrombin III to form a heparin-antithrombin III complex. The complex binds to and irreversibly inactivates thrombin and other activated clotting factors, such as factors IX, X, XI, and XII, thereby preventing the polymerization of fibrinogen to fibrin and the subsequent formation of clots. (NCI Thesaurus)
YOU MAY ALSO LIKE
Heparanase-2 (592 aa, ~67 kDa) is encoded by the human HPSE2 gene. This protein is involved in the proteolysis of heparan sulfate…
Heparanase (543 aa, ~61 kDa) is encoded by the human HPSE gene. This protein plays a role in proteoglycan catabolism.
Heparan-sulfate 6-O-sulfotransferase 2 (605 aa, ~69 kDa) is encoded by the human HS6ST2 gene. This protein plays a role in the sulfation…
Heparan Sulfate Proteoglycan is an extracellular matrix and vascular basal lamina component. Heparan Sulfate is also an essential co-factor in cell-matrix adhesion…
A nanopolymer-based mouthwash formulation containing a mimetic of the glycosaminoglycan (GAG) heparan sulfate, with potential anti-mucositic and protective activities. Upon rinsing with…
A low molecular weight heparin derivative and heparan sulfate proteoglycan (HSPG) mimetic with no or minimal anticoagulant activity and potential antineoplastic…
