Library / English Dictionary

    HETEROZYGOSITY

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    The state of being heterozygous; having two different alleles of the same geneplay

    Classified under:

    Nouns denoting stable states of affairs

    Hypernyms ("heterozygosity" is a kind of...):

    state (the way something is with respect to its main attributes)

    Antonym:

    homozygosity (the state of being homozygous; having two identical alleles of the same gene)

    Derivation:

    heterozygous (having dissimilar alleles at corresponding chromosomal loci)

    Credits

     Context examples: 

    Autosomal recessive inheritance refers to genetic conditions that occur only when mutations are present in both copies of a given gene (i.e., the person is homozygous for a mutation, or carries two different mutations of the same gene, a state referred to as compound heterozygosity).

    (Autosomal Recessive Inheritance, NCI Dictionary)

    Cytogenetics Shared Resource provides Cancer Center members with support in following areas: routine cytogenetic (such as giemsa (G)-banding on fibroblast, lymphoblast or somatic cell hybrid lines to determine karyotypes, etc.), fluorescence in situ hybridization (FISH) for clarification of karyotypes, and SKY (spectral karyotyping), to analyze chromosomal changes, microsatellite analysis of tumors for loss of heterozygosity, mutation analysis of tumors, chimerism studies of bone marrow transplants; maintenance of cell lines and lymphocytes.

    (Cytogenetics Shared Resource, NCI Thesaurus)


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