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    HYPERSENSITIVITY

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    Extreme sensitivityplay

    Classified under:

    Nouns denoting cognitive processes and contents

    Hypernyms ("hypersensitivity" is a kind of...):

    sensibility; sensitiveness; sensitivity ((physiology) responsiveness to external stimuli; the faculty of sensation)

    Derivation:

    hypersensitive (having an allergy or peculiar or excessive susceptibility (especially to a specific factor))

    Sense 2

    Meaning:

    Pathological sensitivityplay

    Classified under:

    Nouns denoting stable states of affairs

    Hypernyms ("hypersensitivity" is a kind of...):

    predisposition; sensitivity (susceptibility to a pathogen)

    Hyponyms (each of the following is a kind of "hypersensitivity"):

    cryaesthesia; cryesthesia (hypersensitivity to cold)

    hypersensitivity reaction (an inappropriate and excessive reaction to an allergen (as pollen or dust or animal hair or certain foods); severity ranges from mild allergy to severe systemic reactions leading to anaphylactic shock)

    Derivation:

    hypersensitive (having an allergy or peculiar or excessive susceptibility (especially to a specific factor))

    Credits

     Context examples: 

    Conjunctivitis due to hypersensitivity to various allergens.

    (Atopic Conjunctivitis, NLM, Medical Subject Headings)

    Nedocromil inhibits the activation and release of inflammatory mediators (leukotrienes, histamine and prostaglandins) from a variety of cells involved in hypersensitivity reactions, including mast cells, eosinophils, neutrophils, macrophages, monocytes and platelets.

    (Nedocromil Calcium, NCI Thesaurus)

    Systemic anaphylaxis is the most dramatic example of an immediate hypersensitivity reaction; is uncommon and unexpected in nature and occasionally results in a fatal outcome.

    (Anaphylactic shock, Food and Drug Administration)

    Red discoloration of the skin caused by infectious agents, drug hypersensitivity, or underlying diseases.

    (Erythema, NCI Thesaurus)

    Due to their ability to kill antigen-presenting cells and their lymphokine-mediated effector activity, these cells are associated with delayed-type hypersensitivity reactions.

    (Murine Th1 Cells, NCI Thesaurus)

    Docetaxel emulsion ANX-514 is formulated without polysorbate 80 or other detergents in order to reduce the incidence and severity of hypersensitivity reactions.

    (Docetaxel Emulsion ANX-514, NCI Thesaurus)

    Nedocromil sodium inhibits the activation and release of inflammatory mediators (leukotrienes, histamine and prostaglandins) from a variety of cells involved in hypersensitivity reactions, including mast cells, eosinophils, neutrophils, macrophages, monocytes and platelets.

    (Nedocromil Sodium, NCI Thesaurus)

    The vitamin-E based emulsion allows bolus infusion without steroid premedication and may diminish hypersensitivity reactions.

    (Paclitaxel Vitamin E-Based Emulsion, NCI Thesaurus)

    The Erwinia-derived product is often used for those patients who have experienced a hypersensitivity reaction to the E. Coli formulation.

    (asparaginase Erwinia chrysanthemi, NCI Thesaurus)

    Contact hypersensitivity is an inflammatory response induced by antigen-reactive T cells that are exposed to antigen on the skin surface (epidermis).

    (Contact Hypersensitivity, NCI Thesaurus)


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