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Hypogammaglobulinemia
Pronunciation
Definition 1
A condition in which the level of immunoglobulins (antibodies) in the blood is low and the risk of infection is high. (NCI Dictionary)
Definition 2
A decreased level of serum immunoglobulins. It may be inherited or acquired. It is caused by decreased or inefficient production of immunoglobulins from B cells or by a decrease in the numbers of B cells themselves. Low levels of immunoglobulins will affect the immune system's ability to combat bacterial infection. Supplementation of immunoglobulins is needed to prevent worsening outcomes. (NCI Thesaurus)
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