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HYPOTHALAMIC
| Pronunciation (US): |  | (GB): | |
I. (adjective)
Sense 1
Meaning:
Of or relating to the hypothalamus
Classified under:
Relational adjectives (pertainyms)
Pertainym:
hypothalamus (a basal part of the diencephalon governing autonomic nervous system)
Derivation:
hypothalamus (a basal part of the diencephalon governing autonomic nervous system)
Context examples:
The synthesis and release of growth hormone (GH) from the pituitary are controlled by the hypothalamic hormones GH-releasing hormone (GHRH) and somatostatin (SRIF), which in turn are regulated by feedback from blood GH and insulin-like growth factor-I (IGF-I) concentrations.
(Food Intake and Energy Homeostasis Pathway, NCI Thesaurus/BIOCARTA)
Through projections to various brain regions including relay nuclei of the autonomic nervous system, hypothalamic regions and the central nucleus of the amygdala, the BNST controls endocrine and autonomic reactions in response to emotionally-salient stimuli, along with behavioral expression of anxiety and fear, Science Daily reported.
(The Secret Connection between Anxiety, Sleep, The Titi Tudorancea Bulletin)
As a selective estrogen receptor modulator (SERM), enclomiphene binds to hypothalamic estrogen receptors, blocking the negative feedback of endogenous estrogens and stimulating the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus; released GnRH subsequently stimulates the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary, resulting in ovulation.
(Enclomiphene Citrate, NCI Thesaurus)
Specifically expressed in hypothalamic neurons as a preproprotein, Gonadotropin Releasing Hormones (GnRH Family) are secreted into the median eminence capillary plexus, bind to receptors on anterior pituitary gonadotrophs, and stimulate release of LHRH and FSH gonadotropins to control female reproduction.
(Gonadotrophin Releasing Hormone, NCI Thesaurus)
Alprazolam binds to a specific site distinct from the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) binding site on the benzodiazepine-GABA-A-chloride ionophore receptor complex located in the limbic, thalamic and hypothalamic regions of the central nervous system (CNS).
(Alprazolam, NCI Thesaurus)
Specifically expressed as a 92-aa 10-kDa precursor in a small population of hypothalamic neurons by human GNRH1 Gene (GnRH Family), Gonadotropin Releasing Hormone 1 is secreted into the median eminence capillary plexus and stimulates release of LHRH and FSH from anterior pituitary gonadotropes to control female reproduction.
(Gonadotropin Releasing Hormone 1, NCI Thesaurus)
This allele, which encodes leptin receptor protein, plays a role in the regulation of adipose-tissue mass through hypothalamic effects on satiety and energy expenditure.
(LEPR wt Allele, NCI Thesaurus)
In agreement with previous studies, the researchers found that a majority (52.8%) of hypothalamic MCH cells fired when mice underwent REM sleep whereas about 35% fired only when the mice were awake and about 12% fired at both times.
(The brain may actively forget during dream sleep, National Institutes of Health)
