IKZF1/BCL6 Fusion Gene

A fusion gene that results from a chromosomal translocation t(3;7)(q27;p12) which fuses the promoter of the IKZF1 gene near the 5' end of the BCL6 gene. This rearrangement is associated with aberrant expression of the BCL6 gene product and B-cell non-Hodgkin lymphoma. (NCI Thesaurus)

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IKZF1 wt Allele

Human IKZF1 wild-type allele is located within 7p13-p11.1 and is approximately 123 kb in length. This allele, which encodes DNA-binding protein Ikaros,…

IKZF1 Gene

This gene is involved in B-cell and T-cell maturation.

IKBKG wt Allele

Human IKBKG wild-type allele is located in the vicinity of Xq28 and is approximately 25 kb in length. This allele, which encodes…

IKBKG Gene

This gene plays a role in the regulation of signal transduction.

IKBKB wt Allele

Human IKBKB wild-type allele is located in the vicinity of 8p11.2 and is approximately 61 kb in length. This allele, which encodes…

IKBKB Gene

This gene is involved in protein phosphorylation.