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IMMUNOSUPPRESSIVE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A drug that lowers the body's normal immune response
Synonyms:
immune suppressant drug; immunosuppressant; immunosuppressive; immunosuppressive drug; immunosuppressor
Classified under:
Nouns denoting man-made objects
Hypernyms ("immunosuppressive" is a kind of...):
medicament; medication; medicinal drug; medicine ((medicine) something that treats or prevents or alleviates the symptoms of disease)
Hyponyms (each of the following is a kind of "immunosuppressive"):
mercaptopurine; Purinethol (a drug (trade name Purinethol) that interferes with the metabolism of purine and is used to treat acute lymphocytic leukemia)
amethopterin; methotrexate; methotrexate sodium (toxic antimetabolite that limits cellular reproduction by acting as an antagonist to folic acid; used to treat certain cancers and psoriasis and rheumatoid arthritis)
II. (adjective)
Sense 1
Meaning:
Of or relating to a substance that lowers the body's normal immune response and induces immunosuppression
Classified under:
Relational adjectives (pertainyms)
Pertainym:
immunosuppression (lowering the body's normal immune response to invasion by foreign substances; can be deliberate (as in lowering the immune response to prevent rejection of a transplanted organ) or incidental (as a side effect of radiotherapy or chemotherapy for cancer))
Context examples:
A Fc-modified, humanized monoclonal antibody directed against the B-cell CD20 cell surface antigen, with immunosuppressive activity.
(Ocrelizumab, NCI Thesaurus)
Mycophenolate mofetil is a type of immunosuppressive agent.
(Mycophenolate mofetil, NCI Dictionary)
The anhydrous form of mercaptopurine, a thiopurine-derivative antimetabolite with antineoplastic and immunosuppressive activities.
(Mercaptopurine Anhydrous, NCI Thesaurus)
A murine IgG2a monoclonal antibody with immunosuppressive activity.
(muromonab-CD3, NCI Thesaurus)
A purine analogue with cytotoxic and immunosuppressive activity.
(Azathioprine, NCI Thesaurus)
As TGFs are potent immunosuppressive cytokines, reducing their levels may activate the immune system locally and this may eventually cause a cytotoxic T-lymphocyte (CTL) response against the tumor cells.
(bi-shRNA-Furin/GM-CSF-Expressing Autologous Tumor Cell Vaccine, NCI Thesaurus)
A purified gamma immunoglobulin (IgG) with immunosuppressive activity.
(Anti-Thymocyte Globulin, NCI Thesaurus)
A synthetic glucocorticoid receptor agonist that mimics the metabolic, anti-inflammatory, and immunosuppressive activity of the natural glucocorticoids.
(Amcinonide, NCI Thesaurus)
Alclometasone dipropionate is a glucocorticoid receptor agonist that mimics the metabolic, anti-inflammatory, immunosuppressive, antipruritic, and vasoconstrictive effects of natural glucocorticoids.
(Alclometasone Dipropionate, NCI Thesaurus)
A synthetic derivative of pterins with antineoplastic and immunosuppressive properties.
(Aminopterin, NCI Thesaurus)
