Health / Medical Topics

    Interleukin-3

    Pronunciation

    Definition 1

    One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. Interleukin-3 is made mainly by a type of T lymphocyte. It increases the number of blood cells made by the bone marrow. Interleukin-3 made in the laboratory is used as a biological response modifier to boost the immune system in cancer therapy. Interleukin-3 is a type of cytokine. Also called IL-3. (NCI Dictionary)

    Definition 2

    Human interleukin-3 (152 aa, 17 kDa precursor) is encoded by the human interleukin-3 (IL3) gene. This protein is a potent growth-promoting cytokine that enhances the ability of the immune system to fight tumor cells. IL-3 supports proliferation of many hematopoietic cell types. It is involved in cell growth, differentiation and apoptosis in addition to possessing neurotrophic activity. Abnormalities in this protein may be associated with neurologic disorders. (NCI Thesaurus)




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