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INWARDLY
Pronunciation (US): | (GB): |
I. (adverb)
Sense 1
Meaning:
With respect to private feelings
Example:
inwardly, she was raging
Synonyms:
inside; inwardly
Classified under:
Antonym:
outwardly (in outward appearance)
Pertainym:
inward (relating to or existing in the mind or thoughts)
Context examples:
The analgesic effect of fentanyl is likely due to its metabolite morphine, which induces opening of G-protein-coupled inwardly rectifying potassium (GIRK) channels and blocks the opening of N-type voltage-gated calcium channels, thereby resulting in hyperpolarization and reduced neuronal excitability.
(Fentanyl, NCI Thesaurus)
Stimulation of the mu-receptor inhibits adenyl cyclase activity, induces opening of G-protein-coupled inwardly rectifying potassium (GIRK) channels, and blocks the opening of N-type voltage-gated calcium channels, resulting in hyperpolarization and reduced neuronal excitability; in addition, neuronal release of neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline may decrease.
(Fentanyl Matrix Transdermal Patch, NCI Thesaurus)
The analgesic effect of codeine sulfate is likely due to its metabolite morphine, which induces opening of G-protein-coupled inwardly rectifying potassium (GIRK) channels and blocks the opening of N-type voltage-gated calcium channels, thereby resulting in hyperpolarization and reduced neuronal excitability.
(Codeine Sulfate, NCI Thesaurus)
“So too can brother Porphyry, who was with me, and brother Mark of the Spicarium, who hath been so much stirred and inwardly troubled by the sight that he now lies in a fever through it.”
(The White Company, by Sir Arthur Conan Doyle)
Stimulation of mu-subtype opioid receptors results in a decrease in the release of nociceptive neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline; in addition, the codeine metabolite morphine induces opening of G-protein-coupled inwardly rectifying potassium (GIRK) channels and blocks the opening of N-type voltage-gated calcium channels, resulting in hyperpolarization and reduced neuronal excitability.
(Codeine, NCI Thesaurus)
Mate now more demoralised than either of men. His stronger nature seems to have worked inwardly against himself. Men are beyond fear, working stolidly and patiently, with minds made up to worst. They are Russian, he Roumanian.
(Dracula, by Bram Stoker)
A weakness, beginning inwardly, extending to the limbs, seized me, and I fell: I lay on the ground some minutes, pressing my face to the wet turf.
(Jane Eyre, by Charlotte Brontë)
I had steeled myself to brazen it out, though I was trembling inwardly; but the enormous strength of the man was too much for my fortitude.
(The Sea-Wolf, by Jack London)
He shook the snow from his hat and clothes, and brushed it away from his face, while I was inwardly making these remarks.
(David Copperfield, by Charles Dickens)
He went back to the hotel gladly, with a feeling of satisfaction in that the comfortable Morris chair was waiting for him; and he groaned inwardly, on entering his room, at sight of Joe in the Morris chair.
(Martin Eden, by Jack London)