Health / Medical Topics

    Ionomycin

    Pronunciation

    Definition 1

    An antibiotic drug used to treat infection. (NCI Dictionary)

    Definition 2

    A polyether antibiotic isolated from Streptomyces conglobatus sp. nov. Trejo with antineoplastic activity. Ionomycin is a calcium ionophore that increases intracellular Ca++ levels, possibly relating to endonuclease activation of lymphocytes and decreased ratio of Bcl-2 to Bax and ultimately apoptosis. In addition, this agent is used to investigate the role of intracellular calcium in cellular processes. (NCI Thesaurus)




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