Health / Medical Topics |
ITGAV wt Allele
Human ITGAV wild-type allele is located within 2q31-q32 and is approximately 90 kb in length. This allele, which encodes integrin alpha-V protein, is involved in cellular adhesion and signal transduction. Variant alleles are associated with several types of human cancer and play a role in metastasis. (NCI Thesaurus)
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