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KERATIN
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A fibrous scleroprotein that occurs in the outer layer of the skin and in horny tissues such as hair, feathers, nails, and hooves
Synonyms:
Classified under:
Hypernyms ("keratin" is a kind of...):
albuminoid; scleroprotein (a simple protein found in horny and cartilaginous tissues and in the lens of the eye)
Holonyms ("keratin" is a substance of...):
feather; plumage; plume (the light horny waterproof structure forming the external covering of birds)
hair (a covering for the body (or parts of it) consisting of a dense growth of threadlike structures (as on the human head); helps to prevent heat loss)
horn (the material (mostly keratin) that covers the horns of ungulates and forms hooves and claws and nails)
Context examples:
A morphologic finding indicating the presence of keratin in a tissue sample.
(Keratin Present, NCI Thesaurus)
Keratin, type I cytoskeletal 10 (584 aa, ~59 kDa) is encoded by the human KRT10 gene.
(Keratin, Type I Cytoskeletal 10, NCI Thesaurus)
An autosomal recessive inherited skin disorder caused by mutations in the genes encoding keratins 5 and 14, collagen VII or laminin 5.
(Epidermolysis bullosa, NCI Thesaurus)
A condition marked by thickening of the outer layer of the skin, which is made of keratin (a tough, protective protein).
(Hyperkeratosis, NCI Dictionary)
A pathologic process characterized by the proliferation of keratinizing squamous epithelium resulting in the accumulation of keratin and cells in the middle ear and/or mastoid.
(Cholesteatoma, NCI Thesaurus)
A benign cystic epithelial neoplasm featuring a central keratin mass surrounded by squamous epithelium.
(Cystic Keratinizing Epithelioma, NCI Thesaurus/CDISC)
A cystic lesion with a central keratin mass which is surrounded by squamous epithelium.
(Cystic Keratinizing Epithelioma, NCI Thesaurus)
A variant of cervical squamous cell carcinoma characterized by the presence of keratin pearls.
(Cervical Keratinizing Squamous Cell Carcinoma, NCI Thesaurus)
The diagnosis of squamous cell carcinoma of the bladder should be reserved for those tumors that are predominantly keratin forming.
(Bladder Squamous Cell Carcinoma, NCI Thesaurus)
A non-neoplastic lesion characterized by the proliferation of keratinizing squamous epithelium in the middle ear that results in the accumulation of keratin and cells.
(Middle Ear Cholesteatoma, NCI Thesaurus)
