Health / Medical Topics

    KSA-KLH Conjugate Vaccine

    A peptide vaccine containing an epitope of human tumor-associated KSA antigen (Ep-CAM) conjugated with keyhole limpet hemocyanin (KLH), with potential antineoplastic activity. KSA antigen, a type-I transmembrane glycoprotein and a cellular adhesion molecule with a molecular mass of 40 kDa, is overexpressed on the majority of epithelial tumor cells. KSA antigen is conjugated with KLH, an immunostimulant and a hapten carrier, to enhance immune recognition. Vaccination with KSA-KLH may result in the production of antibodies as well as eliciting a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing the KSA antigen. (NCI Thesaurus)




    YOU MAY ALSO LIKE

    A nonparametric test for finding if three or more independent samples come from populations having the same distribution. It is a nonparametric…
    A tumor in the ovary caused by the spread of stomach cancer.
    Krueppel-like factor 6 (283 aa, ~32 kDa) is encoded by the human KLF6 gene. This protein plays a role in the activation…
    Krueppel-like factor 5 (457 aa, ~51 kDa) is encoded by the human KLF5 gene. This protein plays a role in transcriptional…
    Krueppel-like factor 4 (470 aa, ~50 kDa) is encoded by the human KLF4 gene. This protein regulates transcription.
    Krueppel-like factor 1 (362, ~38 kDa) is encoded by the human KLF1 gene. This protein is involved in transcriptional regulation during erythroid…

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact