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Lenalidomide
Pronunciation
Definition 1
A drug that is similar to thalidomide, and is used to treat multiple myeloma and certain types of anemia. It is also used to treat mantle cell lymphoma that has come back or has not gotten better after other treatment. It is being studied in the treatment of other conditions and types of cancer. Lenalidomide may help the immune system kill abnormal blood cells or cancer cells. It may also prevent the growth of new blood vessels that tumors need to grow. It is a type of antiangiogenesis agent and a type of immunomodulating agent. Also called CC-5013 and Revlimid. (NCI Dictionary)
Definition 2
A thalidomide analog with potential antineoplastic activity. Lenalidomide inhibits TNF-alpha production, stimulates T cells, reduces serum levels of the cytokines vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), and inhibits angiogenesis. This agent also promotes G1 cell cycle arrest and apoptosis of malignant cells. (NCI Thesaurus)
Definition 3
A drug that is similar to thalidomide, and is used to treat multiple myeloma and certain types of anemia. It is also being studied in the treatment of other types of cancer. Lenalidomide belongs to the family of drugs called angiogenesis inhibitors. (NCI Dictionary)
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