Ligand Binding

Ligand Binding is the tight and specific (high affinity) interaction between a small molecule (typically) and a macromolecule (usually protein) that ordinarily results in modification of its function, e.g., antigen-antibody binding, hormone- or neurotransmitter-receptor binding. (NCI Thesaurus)

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Ligand

An ion, molecule or molecular group that binds to a substance to form a larger complex.

Ligamentum Flavum

The fibrous tissues connecting the laminae of neighboring vertebrae beginning at C2 and ending at S1.

Ligament

Band of fibrous tissue connecting bone to bone or cartilage to bone thereby supporting or strengthening a joint.

LIG4 wt Allele

Human LIG4 wild-type allele is located within 13q33-q34 and is approximately 11 kb in length. This allele, which encodes DNA ligase 4…

LIG4 Gene

This gene plays a critical role in the regulation of nonhomologous DNA end joining and in V(D)J recombination.

LIG1 wt Allele

Human LIG1 wild-type allele is located within 19q13.2-q13.3 and is approximately 55 kb in length. This allele, which encodes DNA ligase 1…