Lomustine

Pronunciation

Definition 1

A drug used to treat brain tumors that have already been treated with surgery or radiation therapy. It is also used to treat Hodgkin lymphoma that has not gotten better with other types of treatment or has come back. It is being studied in the treatment of other types of cancer. Lomustine damages the cell's DNA and may kill cancer cells. It is a type of alkylating agent. Also called CCNU and CeeNU. (NCI Dictionary)

Definition 2

A nitrosourea with antineoplastic activity. Lomustine alkylates and crosslinks DNA, thereby inhibiting DNA and RNA synthesis. This agent also carbamoylates DNA and proteins, resulting in inhibition of DNA and RNA synthesis and disruption of RNA processing. Lomustine is lipophilic and crosses the blood-brain barrier. (NCI Thesaurus)

Definition 3

An anticancer drug that belongs to the family of drugs called alkylating agents. (NCI Dictionary)

YOU MAY ALSO LIKE

Lomitapide Mesylate

A methanesulfonic acid form of lomitapide, a small molecule inhibitor of microsomal triglyceride transfer protein.

Lomitapide

A small molecule inhibitor of microsomal triglyceride transfer protein (MTP), an enzyme located in the lumen of the endoplasmic reticulum responsible for…

Lometrexol Sodium

The sodium salt form of lometrexol, a folate analogue antimetabolite with antineoplastic activity. As the stereoisomer of 5,10-dideazatetrahydrofolate, lometrexol selectively inhibits glycinamide…

Lometrexol

A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called antifolates.

Lomefloxacin Hydrochloride

The hydrochloride salt form of lomefloxacin, a synthetic broad-spectrum fluoroquinolone with antibacterial activity. Lomefloxacin hydrochloride inhibits DNA gyrase, a type II topoisomerase…

Lomefloxacin

A synthetic broad-spectrum fluoroquinolone with antibacterial activity. Lomefloxacin inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of…