LRP2 wt Allele

Human LRP2 wild-type allele is located in the vicinity of 2q31.1 and is approximately 236 kb in length. This allele, which encodes low-density lipoprotein receptor-related protein 2, is involved in the endocytosis of lipoproteins, extracellular matrix proteins and secreted proteases. Mutation of the gene is associated with Donnai-Barrow syndrome. (NCI Thesaurus)

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LRP2 Gene

This gene plays a role in receptor-mediated endocytosis.

LRP1B wt Allele

Human LRP1B wild-type allele is located in the vicinity of 2q21.2 and is approximately 1900 kb in length. This allele, which encodes…

LRP1B Gene

This gene plays a role in low density lipoprotein metabolism.

LRP1 wt Allele

Human LRP1 wild-type allele is located within 12q13-q14 and is approximately 85 kb in length. This allele, which encodes prolow-density lipoprotein receptor-related…

LRP1 Gene

This gene is involved in the regulation of endocytosis.

LRP-1-targeted Peptide-drug Conjugate GRN1005

A peptide-drug conjugate containing the taxane paclitaxel covalently linked to the proprietary 19 amino acid peptide angiopep-2, in a 3:1 ratio, with…