| Health / Medical Topics |
Luminal A Breast Carcinoma
A biologic subset of breast carcinoma with a unique molecular signature or expression profile, defined by high expression of genes characteristic of luminal epithelial cells, including estrogen receptors (ER), estrogen regulated protein LIV-1, and the transcription factors hepatocyte nuclear factor 3, HNF3A, XBP1, and GATA 3. This subtype of breast cancer is associated with a good prognosis. (NCI Thesaurus)
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