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LUTETIUM
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I. (noun)
Sense 1
Meaning:
A trivalent metallic element of the rare earth group; usually occurs in association with yttrium
Synonyms:
atomic number 71; Lu; lutecium; lutetium
Classified under:
Hypernyms ("lutetium" is a kind of...):
metal; metallic element (any of several chemical elements that are usually shiny solids that conduct heat or electricity and can be formed into sheets etc.)
Context examples:
The antibody moiety of lutetium Lu-177-DOTA-chimeric monoclonal antibody cG250 binds to renal cell carcinoma (RCC) cells expressing the RCC-associated antigen G250; a cytotoxic dose of beta radiation is selectively delivered to G250-expressing RCC cells upon internalization of the radioimmunoconjugate.
(Lutetium Lu-177 Girentuximab, NCI Thesaurus)
A radioconjugate consisting of the somatostatin analogue edotreotide labeled with lutetium Lu 177 with potential antineoplastic activities.
(Lutetium Lu 177-Edotreotide, NCI Thesaurus)
A radioconjugate consisting of the tyrosine-containing somatostatin analog Tyr3-octreotate (TATE) conjugated with the bifunctional, macrocyclic chelating agent tetra-azacyclododecanetetra-acetic acid (DOTA) and radiolabeled with the beta-emitting radioisotope lutetium Lu 177 with potential antineoplastic activities.
(Lutetium Lu 177-DOTA-TATE, NCI Thesaurus)
Lutetium Lu 177-capromab binds to human prostate specific membrane antigen (PSMA) expressed on tumor cell surfaces via its capromab moiety and, upon internalization, delivers cytotoxic beta radiation directly to PSMA-expressing tumor cells.
(Lutetium Lu-177 Capromab, NCI Thesaurus)
A radioimmunoconjugate, which consists of a monoclonal antibody against the cell-surface antigen CD37 covalently linked, via the bifunctional, macrocyclic chelating agent tetra-azacyclododecanetetra-acetic acid (DOTA), to the beta-emitting radioisotope lutetium Lu 177, with potential antineoplastic activity.
(Lutetium Lu 177 DOTA-Tetulomab, NCI Thesaurus)
