Health / Medical Topics |
Lymphoma TAA-specific Cytotoxic T Lymphocytes
A population of autologous cytotoxic T lymphocytes (CTLs) with potential immunomodulating and antitumor activities. White blood cells are grown ex-vivo and are exposed to dendritic cells (DCs) loaded with lymphoma tumor associated antigens (TAAs); the TAA-specific CTLs are further expanded ex-vivo before being introduced into the patient. Upon infusion with TAA-specific CTLs, these CTLs may help activate tumor-specific CTL responses in the patient, thereby specifically killing TAA-expressing cancer cells and eventually inhibiting tumor cell proliferation. (NCI Thesaurus)
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Metastatic or locally originating neoplasm of lymphocytes.
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The determination of the ratio of lymphoma cells compared to lymphocytes present in a sample. The measurement may be expressed as a…
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The determination of the number of lymphoma cells present in a sample.
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A natural killer cell, activated by a soluble cytokine released by a lymphocyte in response to an antigen. It is important in…
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Killer cell lymphocytes activated in the presence of interleukin-2 (IL-2). Lymphokine-activated killer cells (LAKs) are cytotoxic effector cells with an exceptionally…
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