Library / English Dictionary

MEDIATOR

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

A negotiator who acts as a link between parties

Synonyms:

go-between; intercessor; intermediary; intermediator; mediator

Classified under:

Nouns denoting people

Hypernyms ("mediator" is a kind of...):

negotiant; negotiator; treater (someone who negotiates (confers with others in order to reach a settlement))

Hyponyms (each of the following is a kind of "mediator"):

mediatrix (a woman who is a mediator)

conciliator; make-peace; pacifier; peacemaker; reconciler (someone who tries to bring peace)

diplomat (a person who deals tactfully with others)

harmoniser; harmonizer (a mediator who brings one thing into harmonious agreement with another)

interpreter; translator (someone who mediates between speakers of different languages)

marriage broker; matcher; matchmaker (someone who arranges (or tries to arrange) marriages for others)

moderator (someone who mediates disputes and attempts to avoid violence)

second hand (an intermediate person; used in the phrase 'at second hand')

Derivation:

mediate (act between parties with a view to reconciling differences)

Credits

 Context examples: 

Picibanil activates the host immune system by stimulating the activity of natural killer cells, macrophages and lymphocytes, and by enhancing the production of several key immune mediators, including interleukins and tumor necrosis factor.

(Picibanil, NCI Thesaurus)

Pemirolast also prevents inflammatory mediator release from eosinophils.

(Pemirolast, NCI Thesaurus)

The JAK-STAT signaling pathway is a major mediator of cytokine activity.

(Pacritinib, NCI Thesaurus)

Neuropoietic Cytokine glycoproteins act with high affinity through specific receptors as local paracrine or autocrine intercellular mediators to regulate neuronal growth, regeneration, survival, and differentiation.

(Neuropoietic Cytokine, NCI Thesaurus)

Water soluble, NO is produced normally in numerous tissues and is considered to be a mediator of cell-to cell communication; it functions in numerous processes including vasodilation, inflammation, and neurotransmission.

(Nitric Oxide, NCI Thesaurus)

This allele, which encodes BH3-interacting domain death agonist protein, plays a role in the regulation of apoptosis and is a mediator of mitochondrial damage resulting from caspase activation.

(BID wt Allele, NCI Thesaurus)

The synthetic corticosteroid steroid budesonide binds to intracellular glucocorticosteroid receptors (GRs), exhibiting inhibitory activities against multiple cell types and mediators associated with allergic inflammation.

(Budesonide/Formoterol Fumarate Dihydrate Inhalation Aerosol, NCI Thesaurus)

IL1a, an inflammatory mediator, plays a key role in interleukin-mediated tumor cell activity such as angiogenesis, tissue matrix remodeling, metastasis and tumor cell invasion.

(Anti-IL-1 alpha Monoclonal Antibody CA-18C3, NCI Thesaurus)

Natural or synthetic Alpha-adrenergic Blocking Agents selectively bind to adrenergic receptors, or compete with natural adrenergic mediators, and inactivate alpha adrenergic receptors of the sympathetic nervous system.

(Alpha-adrenergic antagonist, NCI Thesaurus)

This gene is a critical biological mediator of several physiological functions.

(ADORA1 Gene, NCI Thesaurus)