Medical Topics
CTCF is central to signaling pathways in immature B cells elicited by cross-linking the Ig BCR and stimulation with TGF. Both stimuli… »
Human CTCF is located within 16q21-22.3 and is approximately 77 kb in length. This allele, which encodes transcriptional repressor CTCF protein, may… »
This gene plays a role in gene regulation. »
Human CTCFL wild-type allele is located in the vicinity of 20q13.31 and is approximately 30 kb in length. This allele, which encodes… »
CTD nuclear envelope phosphatase 1 (244 aa, ~28 kDa) is encoded by the human CTDNEP1 gene. This protein plays a role in… »
This gene plays a role in protein dephosphorylation. »
Human CTDNEP1 wild-type allele is located in the vicinity of 17p13 and is approximately 8 kb in length. This allele, which encodes… »
This gene plays a role in the transcription and processing of pre-mRNA. »
Human CTDSP2 wild-type allele is located within 12q13-q15 and is approximately 27 kb in length. This allele, which encodes carboxy-terminal domain RNA… »
Human CTF1 wild-type allele is located within 16p11.2-p11.1 and is approximately 7 kb in length. This allele, which encodes cardiotrophin-1 protein, is… »
Human CTGF wild-type allele is located in the vicinity of 6q23.1 and is approximately 3 kb in length. This allele, which encodes… »
This gene is involved in the cellular response to arterial injury. »
Human CTHRC1 wild-type allele is located in the vicinity of 8q22.3 and is approximately 11 kb in length. This allele, which encodes… »
Cytotoxic T lymphocytes (CTLs), also known as killer T cells, provide a cell-mediated response to specific foreign antigens associated with cells. CTLs… »
A protein found on T cells (a type of immune cell) that helps keep the body’s immune responses in check. When CTLA-4… »
This gene is involved in T-cell mediation and receptor signal transduction. »
Human CTLA4 wild-type allele is located within 2q33 and is approximately 6 kb in length. This allele, which encodes cytotoxic T-lymphocyte protein… »
A bioassay used in the detection of interleukin-2 (IL-2) or interleukin-4 (IL-4) in the supernatants of in vitro-stimulated cells. It relies… »
This gene is involved in cell adhesion. »
Human CTNNA1 wild-type allele is located in the vicinity of 5q31 and is approximately 210 kb in length. This allele, which encodes… »
This gene is involved in signal transduction and regulation of transcription. »
Human CTNNB1 wild-type allele is located in the vicinity of 3p21 and is approximately 41 kb in length. This allele, which encodes… »
A fusion gene that results from a chromosomal translocation t(3;8)(p21;q12) which fuses the promoter sequence of the CTNNB1 gene upstream of the… »
This gene plays a role in signal transduction. »
Human CTNND1 wild-type allele is located in the vicinity of 11q11 and is approximately 67 kb in length. This allele, which encodes… »
This gene is involved in the regulation of both transcription and signal transduction. »
Human CTNND2 wild-type allele is located 5p15.2 and is approximately 932 kb in length. This allele, which encodes catenin delta-2 protein, plays… »
A synthetic peptide vaccine consisting of the carboxy terminal peptide (CTP) of human beta chorionic gonadotropin (beta-hCG). Vaccination with CTP-37 may… »
A vaccine composed of synthetic peptides derived from beta-human chorionic gonadotropin (hCG) conjugated to diphtheria toxoid. Vaccination with this peptide may… »
This gene plays a role in the proteolytic processing of proteins involved in neuronal cellular processes. »
Human CTSB wild-type allele is located within 8p22 and is approximately 24 kb in length. This allele, which encodes cathepsin B protein,… »
Human CTSD wild-type allele is located in the vicinity of 11p15.5 and is approximately 11 kb in length. This allele, which encodes… »
Human CTSG wild-type allele is located in the vicinity of 14q11.2 and is approximately 3 kb in length. This allele, which encodes… »
Human CTSH wild-type allele is located within 15q24-q25 and is approximately 28 kb in length. This allele, which encodes cathepsin H protein,… »
Human CTSK wild-type allele is located in the vicinity of 1q21 and is approximately 12 kb in length. This allele, which encodes… »
This gene is involved in intracellular protein catabolism. »
Human CTSL wild-type allele is located within 9q21-q22 and is approximately 5 kb in length. This allele, which encodes cathepsin L protein,… »
Human CTSS wild-type allele is located in the vicinity of 1q21 and is approximately 36 kb in length. This allele, which encodes… »
Human CTSZ wild-type allele is located within 20q13 and is approximately 12 kb in length. This allele, which encodes cathepsin Z protein,… »
Human CTTN wild-type allele is located within 11q13 and is approximately 38 kb in length. This allele, which encodes Src substrate cortactin… »
A drug that is used to treat many types of cancer and is being studied in the treatment of other types of… »
CUB and sushi domain-containing protein 1 (3565 aa, ~389 kDa) is encoded by the human CSMD1 gene. This protein may play a… »
CUB domain-containing protein 1 (836 aa, ~93 kDa) is encoded by the human CDCP1 gene. This protein may play a role in… »
Denotes a person from or of Cuba or an American citizen of Cuban decent. »
An object that is comprised of six regular, solid, congruent square faces and has three equal axes at right angles to each… »
A solid or semi-solid in the shape of a three dimensional square. »
A measure of volume in the metric system. One thousand cubic centimeters equal one liter. Also called cc, milliliter, and… »
A traditional unit of volume equal to 1728 cubic inches, or 1/27 cubic yard, or 0.028 316 85 cubic meter (28.316 85… »
A traditional unit of volume equal to 16.3871 cubic centimeters, or 0.5541 US fluid ounce. »
A SI unit of volume or capacity equal to the volume of a cube with edges one meter in length. It is… »
A unit of volume fraction expressed as a volume of the constituent in cubic meters per the volume of the system represented… »
A SI derived unit of specific volume, a property of materials defined as the number of cubic meters occupied by one kilogram… »
A SI unit of volumetric flow rate defined as the rate at which one cubic meter of matter crosses a given surface… »
A drug used to treat certain bacterial skin and bloodstream infections in adults. Cubicin is also being studied in the treatment of… »
A bone on the lateral side of the tarsus between the calcaneus and the fourth and fifth metatarsal bones. »
A cube-shaped epithelial cell. Because a cuboidal cell has a relatively large cytoplasmic volume, it can undertake more complex functions such as… »
The oil extracted from the seeds of Cucumis sativus. Cucumber seed oil is used primarily in skincare preparations. »
A bandlike device or structure that encircles a body part or another device. »
CUGBP Elav-like family member 2 (508 aa, ~54 kDa) is encoded by the human CELF2 gene. This protein plays a role in… »
This gene plays a role in protein degradation and the negative regulation of cell proliferation. »
Human CUL1 wild-type allele is located in the vicinity of 7q36.1 and is approximately 102 kb in length. This allele, which encodes… »
This gene is involved in protein degradation and the negative regulation of cell proliferation. »
Human CUL2 wild-type allele is located in the vicinity of 10p11.21 and is approximately 81 kb in length. This allele, which encodes… »
Human CUL3 wild-type allele is located in the vicinity of 2q36.2 and is approximately 115 kb in length. This allele, which encodes… »
This gene is involved in protein degradation. It also plays a role in cell cycle arrest and DNA repair. »
Human CUL4A wild-type allele is located within 13q34 and is approximately 56 kb in length. This allele, which encodes cullin-4A protein, is… »
This gene plays a role in the regulation of ubiquitination. »
Human CUL4B wild-type allele is located in the vicinity of Xq23 and is approximately 51 kb in length. This allele, which encodes… »
Human CUL5 wild-type allele is located within 11q22-q23 and is approximately 98 kb in length. This allele, which encodes cullin-5 protein, plays… »
An endoscope for examination of a woman's pelvic organs through the vagina. »
Endoscopic examination of a woman's pelvic organs using a culdoscope inserted through the vagina. »
Cullin Family Genes encode Cullin Family Proteins, which are components of SCF ubiquitin ligase complexes or E3 ubiquitin ligase complexes with elongin… »
A protein family whose members are components of ubiquitin ligase complexes, which are involved in ubiquitination and proteasomal degradation of target… »
Cullin-1 (776 aa, ~90 kDa) is encoded by the human CUL1 gene. This protein plays a role in protein ubiquitination and cell… »
Cullin-2 (745 aa, ~87 kDa) is encoded by the human CUL2 gene. This protein is involved in both cell cycle regulation and… »
Cullin-3 (768 aa, ~89 kDa) is encoded by the human CUL3 gene. This protein plays a role in protein ubiquitination and cell… »
Cullin-4A (759 aa, ~88 kDa) is encoded by the human CUL4A gene. This protein is involved in both DNA repair and protein… »
Cullin-4B (895 aa, ~102 kDa) is encoded by the human CUL4B gene. This protein plays a role in both ubiquitination and protein-protein… »
Cullin-5 (780 aa, ~91 kDa) is encoded by the human CUL5 gene. This protein plays a role in both protein ubiquitination and… »
The ability to understand, interact, and work well with people of different cultures. In medicine, one goal of cultural competency is to… »
The inevitable variety in customs, attitudes, practices, and behaviors that exists among groups of individuals from different ethnic, racial, or national backgrounds… »
Groups of individuals that exhibit differing characteristic behavior in customs, attitudes, practices, and behaviors, or are predisposed to certain health histories due… »
The beliefs, values, and behaviors that are shared within a group, such as a religious group or a nation. Culture includes language,… »
A solution, suspension or semi-solid composed of media conducive to microbial growth. »
The liquid that covers cells in a culture dish and contains nutrients to nourish and support the cells. Culture medium may also… »
Any laboratory procedure for growing microorganisms. »
The preparation work required for doing cell or tissue culture. This includes preparation of the medium and of the growth support… »
A human, plant, or animal cell that has been adapted to grow in the laboratory. Cultured cells may be used to diagnose… »
Cells of a single type (human, animal, or plant) that have been adapted to grow continuously in the laboratory and are used… »
A live form of a bacterium that makes lactic acid (a substance that is made from sugars found in milk and is… »
Maintenance of invertebrate tissue after removal from the body, by placing in a vessel with a sterile nutritive medium. »
The growing of microbes in test tube or petri dish type environments »
Propagation of vertebrate animal cells in culture. »
Maintenance of vertebrate tissue after removal from the body, by placing in a vessel with a sterile nutritive medium. »
The oil extracted from the seeds of Cuminum cyminum. Cumin oil is used in treatments of the digestive system. »
Increasing by successive addition. »
In medicine, the total amount of a drug or radiation given to a patient over time; for example, the total dose of… »
The total amount of a substance or radiation that a person is exposed to over time. Cumulative exposure to a harmful substance… »
A factor used to determine at what point in the beam delivery the next change in setup is to take place. … »
A measure of the total risk that a certain event will happen during a given period of time. In cancer research, it… »
One of three (medial, intermediate, or lateral cuneiform) bones in the foot medial to the cuboid bone and between either the first,… »
The two small rod shaped pieces of elastic cartilage on both sides of the aryepiglottic fold which supports the epiglottis laterally and… »
A case in which cancer cells are found in the body, but the place where the cells first started growing (the origin… »
Any part of a device that resembles a bowl-shaped container. »
A dosing unit equal to the amount of active ingredient(s) contained in a cup. »
A circular seal with a depressed center and raised sealing lips. They are designed to contain high pressure in one direction but… »
A creamy, white crystalline substance. Cupferron is used as an analytical reagent to separate copper, iron and vanadium from other metals. Exposure… »
A procedure in which a rounded glass cup is warmed and placed upside down over an area of the body, creating suction… »
A genus of aerobic, Gram negative, rod and cocci shaped bacterium assigned to the phylum Proteobacteria and the family Burkholderiaceae. »
A species of aerobic, Gram negative, rod and coccus shaped bacterium assigned to the phylum Proteobacteria. This species is motile non-fermentative, oxidase… »
Copper ion requiring two electrons to return to its elemental state. »
A characteristic of a medicinal product, specifying that its most predominant agreeable savor detected by the unified sensation of taste and olfactory… »
The A isomer of Curacin compound. Cruacin A inhibits tubulin polymerization, thereby inhibiting mitosis and cell proliferation. »
The B isomer of Curacin compound. Cruacin B inhibits tubulin polymerization, thereby inhibiting mitosis and cell proliferation. »
The C isomer of Curacin compound. Cruacin C inhibits tubulin polymerization, thereby inhibiting mitosis and cell proliferation. »
A class of compounds isolated from a marine cyanobacterium species (blue green alga). Curacin compounds inhibit tubulin polymerization, thereby inhibiting mitosis… »
Surgery to remove all malignant (cancerous) tissue, which is meant to cure the disease. This includes removing part or all of the… »
The person in charge of the care and superintendence of something, especially a collection. »
An East Indian plant that is a member of the ginger family and is used as a spice and food color. The… »
The oil extracted from the root tuber of Curcuma wenyujin. »
The oil extracted from the root tuber of Curcuma xanthorrhiza. Curcuma xanthorrhiza oil is used primarily in skincare preparations. »
A mixture composed of curcuminoid phenols extracted from the plant Curcuma longa (turmeric root) with potent antioxidant and anti-inflammatory properties. Curcumin… »
An oral capsule containing curcumin, green tea extract, Polygonum cuspidatum extract, and soybean extract, with antioxidant and potential chemopreventive activities. The antioxidants… »
The Cure For Lymphoma Foundation (CFL) is a nationwide not-for-profit organization dedicated to funding research and providing support and education for Hodgkins… »
A type of study protocol designed to evaluate intervention(s) aimed to cure a disease or condition. »
Removal of tissue with a curette (a spoon-shaped instrument with a sharp edge). »
A unit of radioactivity in the CGS system, defined as 3.7 E10 atomic disintegrations or other nuclear transformations per second. One curie… »
A unit of specific radioactivity (massic activity) equal to activity of one Curie of the sample with total mass of one… »
A unit of specific radioactivity (massic activity) equal to activity of one Curie of the sample with total mass of one… »
A unit of volumetric radioactivity concentration defined as a concentration of a radionuclide with an activity equal to one curie per unit… »
A unit of specific radioactivity (massic activity) equal to activity of one Curie of the sample with total mass of one… »
A unit of volumetric radioactivity concentration defined as a concentration of a radionuclide with an activity equal to one curie per unit… »
A unit of specific radioactivity (massic activity) equal to activity of one Curie of the sample with total mass of one… »
A unit of volumetric radioactivity concentration defined as a concentration of a radionuclide with an activity equal to one curie per unit… »
The Curly-Coated Retriever is a large, athletic retriever with a distinctive crisp curly coat. The thick black or liver-colored coat of tight… »
Indicates a person who has smoked at least 100 cigarettes in his or her lifetime and who currently smokes every day. … »
A device designed to maintain a current at a specified level regardless of other fluctuations in the system. »
A standardized rating scale developed and copyrighted by Inflexxicon, Inc. which is used to aid clinicians in determining if a patient may… »
An individual who is presently or not long ago worked or offered to assist without pay at a temporary housing facility for… »
An individual who is presently or not long ago worked or offered to assist without pay at an institution where persons are… »
An individual who is presently or not long ago worked or offered to assist without pay at a residential health care facility… »
A proprietary medical nomenclature of the American Medical Association widely used to report medical procedures and services under public and private health… »
An adult who has smoked 100 cigarettes in his or her lifetime and who currently smokes cigarettes. Includes daily smokers and non-daily… »
Indicates a person who has smoked at least 100 cigarettes in his or her lifetime, who smokes now, but does not smoke… »
An electronic device designed to generate a constant current. »
The name of the therapy that is currently being administered. »
A summary of somebody's educational and work experience, usually for the information of possible future employers. »
The curved portion of the nephron. »
A condition in which there is too much cortisol (a hormone made by the outer layer of the adrenal gland) in the… »
A condition in which there is too much cortisol (a hormone made by the outer layer of the adrenal gland) in the… »
Cushing's syndrome is a hormonal disorder. The cause is long-term exposure to too much cortisol, a hormone that your adrenal gland… »
A constellation of signs and symptoms caused by an excess of glucocorticoids. Classic features include moon facies, buffalo hump, obesity, striae and… »
A triangular shaped structure, i.e., one of the triangular segments of heart valve or a raised area of the biting surface of… »
A device consisting of flexible biocompatible membranes, implantable in the cardio-vascular system, designed to prevent retrograde flow of blood but not impede… »
A characteristic of a medicinal product, specifying that its most predominant agreeable savor detected by the unified sensation of taste and olfactory… »
A substance being studied in the treatment of cancer. It blocks the production of a protein called clusterin, which helps cells live… »
To make according to individual requirements or specifications; to make more personalized or tailored for a specific need. »
A wound or cleft resulted from tissue separation into parts or laid open or penetrated with a sharp edge or instrument. … »
An aggressive mature T-cell non Hodgkin lymphoma involving the skin. It is characterized by the presence of a polymorphic cellular infiltrate which… »
A B-cell non-Hodgkin lymphoma arising from the skin. Representative examples include cutaneous marginal zone B-cell lymphoma and cutaneous follicle center… »
Cancer that has spread from the breast to the skin. »
A usually mild form of diphtheria characterized by infection of the skin by corynebacterium diphtheria and the resulting formation of a chronic,… »
A benign or malignant neoplasm arising from the dermis. It is characterized by the presence of neoplastic fibroblastic cells. »
A benign or malignant neoplasm affecting the skin. The tumor is composed of fibrohistiocytic cells, spindle fibrous cells, and histiocytes in… »
A solitary, slowly growing nodular mass, most often affecting the extremities. It is composed of fibrous and histiocytic cells which infiltrate… »
A morphologic variant of cutaneous fibrous histiocytoma characterized by the presence of spindle-shaped fibrohistiocytic cells and increased cellularity. »
A morphologic variant of cutaneous fibrous histiocytoma characterized by the presence of epitheloid fibrohistiocytic cells. »
A morphologic variant of cutaneous fibrous histiocytoma characterized by the presence of spindle-shaped fibrohistiocytic cells and associated acanthosis. »
A morphologic variant of cutaneous fibrous histiocytoma characterized by the presence of xanthomatous fibrohistiocytic cells, giant cells, and hemosiderin deposition. »
An abnormal communication between the skin and another organ or cavity. »
A follicular lymphoma involving the skin. A cutaneous follicular lymphoma may be metastatic to the skin from the lymph nodes or… »
A ganglioneuroma arising from the skin. »
A glomus tumor arising from the skin. It is characterized by the presence of dilated veins surrounded by glomus cells. … »
Hodgkin lymphoma primarily involving the skin. This diagnosis can only be made when there is no evidence of Hodgkin lymphoma in… »
A benign smooth muscle neoplasm arising from the arrector pili muscle, tunica media of blood vessels, and dartos muscle of the… »
An aggressive malignant smooth muscle neoplasm, arising from the skin. It is characterized by a proliferation of neoplastic spindle cells. … »
Leishmaniasis affecting the skin. It is the most common form of leishmaniasis. It presents with erythematous macules and papules, and nodules which… »
A benign adipose tissue neoplasm of the skin. »
A benign or malignant adipose tissue neoplasm of the skin. »
A malignant adipose tissue neoplasm of the skin. »
A form of lupus erythematosus in which the skin may be the only organ involved or in which skin involvement precedes the… »
A lymphangioma arising from the skin. »
A form of mastocytosis characterized by mast cell infiltration of the skin. (WHO, 2001) -- 2003 »
A primary melanoma arising from atypical melanocytes in the skin. Precursor lesions include acquired and congenital melanocytic nevi, and dysplastic… »
A clinical finding about one or more characteristics of cutaneous melanoma, following the rules of the TNM AJCC v6 classification system. TNM… »
A pathologic finding about one or more characteristics of cutaneous melanoma, following the rules of the TNM AJCC v6 classification system as… »
A pathologic finding about one or more characteristics of cutaneous melanoma, following the rules of the TNM AJCC v6 classification system as… »
A pathologic finding about one or more characteristics of cutaneous melanoma, following the rules of the TNM AJCC v6 classification system as… »
A pathologic finding about one or more characteristics of cutaneous melanoma, following the rules of the TNM AJCC v6 classification system. TNM… »
A finding about one or more characteristics of cutaneous melanoma, following the rules of the TNM AJCC v6 classification system. »
A myxoma arising from the dermis. »
Noninvasive measurement or determination of the partial pressure of oxygen and carbon dioxide locally in the capillaries of a tissue by the… »
A skin disease marked by scaly or thickened patches on the skin, and often caused by prolonged exposure to arsenic. The… »
A malignant vascular neoplasm arising from an area of skin exposed to radiation therapy. »
Administration to the skin. »
Formation of non-necrotizing granulomas in the skin. It may be a manifestation of systemic sarcoidosis or may also arise in isolation. … »
An unusual presentation of schistosomiasis characterized by a pruritic papular rash in the perigenital or periumbilical area due to an allergic reaction… »
Any of a group of T-cell non-Hodgkin lymphomas that begins in the skin as an itchy, red rash that can thicken or… »
A T-cell non-Hodgkin lymphoma arising from the skin. Representative examples include mycosis fungoides and primary cutaneous anaplastic large cell lymphoma. »
The thin skeletal muscle within the subcutaneous tissue. »
A rare malignant neoplasm arising from the skin. It is characterized by the presence of spindle cells in a storiform pattern… »
Inflammation of the blood vessel wall characterized by palpable purpura. »
A vein that drains blood from a specific area of the skin. »
A rare, benign wart-like skin lesion of unknown etiology that is usually found in the genital or perianal area and consists of… »
A congenital or acquired disorder affecting the elastic fibers of the skin. It is characterized by loss of elasticity resulting in loosening… »
A device designed to slice or sever a material. »
A cable designed to drive the rotational cutter of a catheter device. »
Human CUX1 wild-type allele is located in the vicinity of 7q22.1 and is approximately 468 kb in length. This allele, which encodes… »
In medicine, a loss of blood flow to part of the brain, which damages brain tissue. CVAs are caused by blood clots… »
Achemoimmunotherapy regimen consisting of cisplatin, vinblastine, dacarbazine, aldesleukin (IL-2), and interferon, used for the treatment of advanced-stage or metastatic malignant melanoma. … »
A regimen consisting of cisplatin, vinblastine and dacarbazine used for the treatment of advanced-stage or metastatic malignant melanoma. »
An abbreviation for a chemotherapy combination used to treat slow-growing forms of non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia (CLL). It includes… »
An abbreviation for a chemotherapy combination used to treat slow-growing forms of non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia (CLL). It includes… »
CX3C chemokine receptor 1 protein (355 aa, 40 kD) is a cell defense protein that is encoded by the human CX3CR1 gene… »
This gene plays a role in both inflammatory processes and cellular adhesion. »
Human CX3CL1 wild-type allele is located within 16q13 and is approximately 13 kb in length. This allele, which encodes fractalkine precursor protein,… »
This gene is involved in leukocyte adhesion and migration. »
Human CX3CR1 wild-type allele is located in the vicinity of 3p22.2 and is approximately 18 kb in length. This allele, which encodes… »
This gene is involved in both cell-cell adhesion and viral infection. »
Human CXADR wild-type allele is located in the vicinity of 21q21.1 and is approximately 81 kb in length. This allele, which encodes… »
CXC Cytokine Genes encode Alpha Chemokines, CXC-type dual-cysteine chemokines with paired cysteine residues separated by a non-cysteine residue in their primary sequence… »
This gene is involved in immune processes and has been implicated in cancer metastasis. »
Human CXCL1 wild-type allele is located within 4q21 and is approximately 14 kb in length. This allele, which encodes Growth-regulated protein alpha… »
This gene plays a role in immune system processes and is involved in angiogenesis. »
Human CXCL10 wild-type allele is located within 4q21 and is approximately 2 kb in length. This allele, which encodes small inducible cytokine… »
This gene is involvd in the regulation of immune responses and cellular responses. »
Human CXCL11 wild-type allele is located in the vicinity of 4q21.2 and is approximately 3 kb in length. This allele, which encodes… »
This gene is involved in chemotaxis and extracellular matrix regulation. »
Human CXCL12 wild-type allele is located in the vicinity of 10q11.1 and is approximately 15 kb in length. This allele, which encodes… »
This gene plays a role in B-cell regulation and intercellular interactions. »
Human CXCL13 wild-type allele is located within 4q21 and is approximately 100 kb in length. This allele, which encodes small inducible cytokine… »
This gene is involved in cellular homeostasis and chemotaxis. »
Human CXCL14 wild-type allele is located within 5q31 and is approximately 9 kb in length. This allele, which encodes small inducible cytokine… »
This gene may be involved in immune-cell chemotaxis. »
Human CXCL16 wild-type allele is located in the vicinity of 17p13 and is approximately 6 kb in length. This allele, which encodes… »
This gene is involved in the regulation of angiogenesis. »
Human CXCL2 wild-type allele is located within 4q21 and is approximately 2 kb in length. This allele, which encodes macrophage inflammatory protein… »
This gene plays a role in inflammatory processes and G-protein coupled receptor signaling. »
Human CXCL3 wild-type allele is located within 4q21 and is approximately 2 kb in length. This allele, which encodes macrophage inflammatory protein… »
This gene plays a role in chemotaxis and neutrophil activation. »
Human CXCL5 wild-type allele is located within 4q12-q13 and is approximately 3 kb in length. This allele, which encodes small inducible cytokine… »
This gene is involved in the regulation of inflammatory processes and neutrophil activation. »
Human CXCL6 wild-type allele is located within 4q21 and is approximately 2 kb in length. This allele, which encodes small inducible cytokine… »
This gene plays a role in T-cell trafficking. »
Human CXCL9 wild-type allele is located within 4q21 and is approximately 6 kb in length. This allele, which encodes small inducible cytokine… »
This gene plays a role in immune cell chemotaxis and trafficking. »
Human CXCR3 wild-type allele is located within Xq13 and is approximately 3 kb in length. This allele, which encodes C-X-C chemokine receptor… »
An orally bioavailable inhibitor of CXC Chemokine Receptor 4 (CXCR4) with potential antineoplastic activity. CXCR4 antagonist BL-8040 selectively binds to the chemokine… »
An orally bioavailable inhibitor of CXC chemokine receptor 4 (CXCR4) with receptor binding and hematopoietic stem cell-mobilization activities. CXCR4 inhibitor TG-0054 binds… »
This gene is involved in the mediation of viral entry into cells and cellular migration and chemotaxis. »
An antagonist of the C-X-C chemokine receptor type 4 (CXCR4). CXCR4, which belongs to the G protein-coupled receptor (GPCR) gene family, plays… »
An orally bioavailable inhibitor of CXCR4 with potential antineoplastic and antiviral activities. CXCR4 inhibitor MSX-122 binds to the chemokine receptor CXCR4, preventing… »
An orally bioavailable inhibitor of CXC chemokine receptor 4 (CXCR4) with receptor binding and hematopoietic stem cell-mobilization activities. CXCR4 inhibitor POL6326 binds… »
An inhibitor of CXC chemokine receptor 4 (CXCR4), with potential antineoplastic activity. Upon subcutaneous administration, CXCR4 inhibitor LY2510924 binds to the chemokine… »
CXCR4 is a chemokine receptor in the GPCR gene family, and is expressed by cells in the immune system and the central… »
Human CXCR4 wild-type allele is located within 2q21 and is approximately 4 kb in length. This allele, which encodes C-X-C chemokine receptor… »
This gene is involved in immune cell chemotaxis. »
Human CXCR6 wild-type allele is located within 3p21 and is approximately 5 kb in length. This allele, which encodes C-X-C chemokine receptor… »
This gene plays a role in signal transduction. »
Human CXCR7 wild-type allele is located in the vicinity of 2q37.3 and is approximately 15 kb in length. This allele, which encodes… »
This gene has no known function. »
Human CXorf67 wild-type allele is located in the vicinity of Xp11.22 and is approximately 2 kb in length. This allele, which encodes… »
Provider: CyThera, Inc., San Diego, CA. No information from provider. This cell line meets the criteria for the use of human embryonic… »
Provider: CyThera, Inc., San Diego, CA. No information from provider. This cell line meets the criteria for the use of human embryonic… »
Provider: CyThera, Inc., San Diego, CA. No information from provider. This cell line meets the criteria for the use of human embryonic… »
Provider: CyThera, Inc., San Diego, CA. No information from provider. This cell line meets the criteria for the use of human embryonic… »
Provider: CyThera, Inc., San Diego, CA. No information from provider. This cell line meets the criteria for the use of human embryonic… »
Provider: CyThera, Inc., San Diego, CA. No information from provider. This cell line meets the criteria for the use of human embryonic… »
Provider: CyThera, Inc., San Diego, CA. No information from provider. This cell line meets the criteria for the use of human embryonic… »
Provider: CyThera, Inc., San Diego, CA. No information from provider. This cell line meets the criteria for the use of human embryonic… »
Provider: CyThera, Inc., San Diego, CA. No information from provider. This cell line meets the criteria for the use of human embryonic… »
A bacterial cell wall mimetic. It is a potent inducer of cytokines and is beginning Phase II trials in combination with… »
A poisonous chemical found in some foods and plants, tobacco smoke, and when certain substances are burned. It is used to make… »
A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Cyanocobalamin helps make… »
An inorganic compound used as a reagent in molecular biology. As a reagent for peptide mapping and amino acid sequence analysis,… »
A plant compound that contains sugar and produces cyanide. »
Episodes of cyanosis that result from breath holding spells in response to anger or frustration, during childhood. These episodes usually resolve in… »
Blue- or purplish-colored body; this is caused by excessive amounts of deoxygenated hemoglobin in the skin vessels of the body. »
Blue- or purplish-colored limbs; this is caused by excessive amounts of deoxygenated hemoglobin in the skin vessels of the limbs. »
A protein isolated from the cyanobacterium Nostoc ellipsosporum with activity against human immunodeficiency virus (HIV). Cyanovirin-N binds to the sugar moieties on… »
Human CYBB wild-type allele is located in the vicinity of Xp21.1 and is approximately 33 kb in length. This allele, which encodes… »
A proprietary, robotic radiosurgery system designed to deliver precise beams of high dose radiation to tumors with extreme accuracy. »
A hybrid cell with cytoplasm (or cytoplasmic components) of one cell inserted into another cell. »
A substance being studied in the treatment of some types of cancer. It blocks certain enzymes involved in cell division and may… »
A semi-synthetic beta-lactam aminocyclohexylpenicillin antibiotic. Cyclacillin is bactericidal and binds to specific penicillin-binding proteins, thereby inhibiting transpeptidation during peptidoglycan synthesis. This leads… »
An event or sequence of events that constitute a round or succession of observable phenomena, recurring usually at regular or approximately regular… »
A unit of frequency equal to the frequency at which one complete execution of a periodically repeated phenomenon, alternation, event, or sequence… »
A unit of frequency equal to the frequency at which one complete execution of a periodically repeated phenomenon, alternation, event, or sequence… »
A complex Cycled study requiring multiple files to describe the conditions. »
A simple Cycled study requiring one file to describe the conditions. »
A promoter sequence which interacts with CRE binding proteins to modulate gene expression in response to the level of cAMP in the… »
Cyclic AMP-dependent transcription factor ATF-1 (271 aa, ~29 kDa) is encoded by the human ATF1 gene. This protein is involved in the… »
Cyclic AMP-dependent transcription factor ATF-2 (505 aa, ~55 kDa) is encoded by the human ATF2 gene. This protein is involved in transcriptional… »
Cyclic AMP-dependent transcription factor ATF-3 (181 aa, ~21 kDa) is encoded by the human ATF3 gene. This protein plays a role in… »
Cyclic AMP-dependent transcription factor ATF-4 (351 aa, ~39 kDa) is encoded by the human ATF4 gene. This protein plays a role in… »
Cyclic AMP-dependent transcription factor ATF-5 (282 aa, ~30 kDa) is encoded by the human ATF5 gene. This protein is involved in the… »
Cyclic AMP-responsive element-binding protein 1 (341 aa, ~37 kDa) is encoded by the human CREB1 gene. This protein plays a role in… »
Cyclic AMP-responsive element-binding protein 3 (395 aa, ~44 kDa) is encoded by the human CREB3 gene. This protein is involved in the… »
Cyclic AMP-responsive element-binding protein 3-like protein 1 (519 aa, ~57 kDa) is encoded by the human CREB3L1 gene. This protein plays a… »
Cyclic AMP-responsive element-binding protein 3-like protein 2 (520 aa, ~57 kDa) is encoded by the human CREB3L2 gene. This protein is involved… »
Cyclic AMP-responsive element-binding protein 3-like protein 3 (461 aa, ~49 kDa) is encoded by the human CREB3L3 gene. This protein plays a… »
Cyclic AMP-responsive element-binding protein 3-like protein 4 (395 aa, ~43 kDa) is encoded by the human CREB3L4 gene. This protein plays a… »
Cyclic AMP-responsive element-binding protein 5 (508 aa, ~57 kDa) is encoded by the human CREB5 gene. This protein is involved in transcriptional… »
The determination of the amount of cyclic citrullinated peptide antibody present in a sample. »
A cyclic compound in which two carbon atoms are linked through an oxygen atom and exposure to these compounds can increase the… »
A cellular regulatory agent that acts as a second messenger. Its levels increase in response to a variety of signals (acetylcholine,… »
Cyclic GMP-AMP synthase (522 aa, ~59 kDa) is encoded by the human MB21D1 gene. This protein plays a role both cyclic dinucleotide… »
The determination of the amount of cyclic guanosine 3,5-monophosphate present in a sample. »
A chronic condition that affects neutrophils (a type of white blood cell). In cyclic neutropenia, the number of neutrophils in the… »
The branch of biochemistry concerned with the metabolism of and biological pathways involving cyclic nucleotides. »
The science concerned with the chemistry, actions, and uses of cyclic nucleoside monophosphates. »
A non-enzymatic regulatory protein that is critical during the cell cycle. The cyclin family members complex with other proteins to modulate the… »
Cyclin-A1 (465 aa, ~52 kDa) is encoded by the human CCNA1 gene. This protein is involved in the G1/S and G2/M cell… »
A cell-based cancer vaccine comprised of autologous dendritic cells (DCs) pulsed with cyclin B1 peptide, with potential immunostimulatory and antineoplastic activities. Upon… »
A protein family that is synthesized during the G1 phase of the cell cycle and drives the G1/S phase transition through the… »
A benzyl styryl sulfone analog, and a disodium phosphate ester prodrug of ON 013100, with potential antineoplastic activity. Upon hydrolysis, cyclin D… »
Cyclins are proteins that associate with cyclin-dependent protein kinases to regulate their activity and the progression of the cell cycle through specific… »
These genes encode member proteins of the highly conserved cyclin family. They are characterized by a dramatic periodicity in protein abundance through… »
The cell cycle is regulated by the interplay of many molecules. Key among these are the cyclins which are expressed and then… »
Cyclin-A2 (432 aa, ~49 kDa) is encoded by the human CCNA2 gene. This protein is involved in the regulation of both the… »
Cyclin-C (283 aa, ~33 kDa) is encoded by the human CCNC gene. This protein plays a role in the regulation of the… »
A protein that helps control cell division. It is found in higher than normal amounts in several types of cancer cells. Measuring… »
Cyclin-dependent kinases are eukaryotic, phosphoregulated protein kinases that associate with cyclins to control cell cycle progression. »
Cyclin-dependent kinase 1 (297 aa, ~34 kDa) is encoded by the human CDK1 gene. This protein is involved in protein phosphorylation and… »
Cyclin-dependent kinase 10 (360 aa, ~41 kDa) is encoded by the human CDK10 gene. This protein plays a role in cell cycle… »
Cyclin-dependent kinase 11B (795 aa, ~93 kDa) is encoded by the human CDK11B gene. This protein is involved in the modulation of… »
Cyclin-dependent kinase 12 (1490 aa, ~164 kDa) is encoded by the human CDK12 gene. This protein is involved in the regulation of… »
Cyclin-dependent kinase 16 (496 aa, ~56 kDa) is encoded by the human CDK16 gene. This protein is involved in both signaling and… »
Cyclin-dependent kinase 2 (298 aa, ~34 kDa) is encoded by the human CDK2 gene. This protein is involved in the regulation of… »
Cyclin-dependent kinase 2-associated protein 1 (115 aa, ~12 kDa) is encoded by the human CDK2AP1 gene. This protein may be involved in… »
Cyclin-dependent kinase 2-associated protein 2 (126 aa, ~13 kDa) is encoded by the human CDK2AP2 gene. This protein may play a role… »
Cyclin-dependent kinase 3 (305 aa, ~35 kDa) is encoded by the human CDK3 gene. This protein may play a role in cell… »
Cyclin-dependent kinase 4 (303 aa, ~34 kDa) is encoded by the human CDK4 gene. This protein may be involved in cell cycle… »
Cyclin-dependent kinase 4 inhibitor B (138 aa, ~15 kDa) is encoded by the human CDKN2B gene. This protein plays a role in… »
Cyclin-dependent kinase 4 inhibitor C (168 aa, ~18 kDa) is encoded by the human CDKN2C gene. This protein plays a role in… »
Cyclin-dependent kinase 5 (292 aa, ~33 kDa) is encoded by the human CDK5 gene. This protein plays a role in protein phosphorylation… »
Cyclin-dependent kinase 5 activator 1 (307 aa, ~34 kDa) is encoded by the human CDK5R1 gene. This protein is involved in the… »
Cyclin-dependent kinase 6 (326 aa, ~37 kDa) is encoded by the human CDK6 gene. This protein plays a role in both protein… »
Cyclin-dependent kinase 7 (346 aa, ~39 kDa) is encoded by the human CDK7 gene. This protein is involved in the mediation of… »
Cyclin-dependent kinase 8 (464 aa, ~53 kDa) is encoded by the human CDK8 gene. This protein plays a role in the modulation… »
Cyclin-Dependent Kinase Genes encode Cyclin-Dependent Kinases, eukaryotic phosphoregulated protein kinases that physically associate with cyclins to achieve full enzymatic activity and control… »
Any substance that inhibits cyclin-dependent kinase (CDK), an enzyme that catalyzes the addition of a phosphate group to a protein in the… »
Cyclin-dependent kinase inhibitor 1 (164 aa, ~18 kDa) is encoded by the human CDKN1A gene. This protein is involved in cell cycle… »
Cyclin-dependent kinase inhibitor 1B (198 aa, ~22 kDa) is encoded by the human CDKN1B gene. This protein plays a role in cell… »
Cyclin-dependent kinase inhibitor 1C (316 aa, ~32 kDa) is encoded by the human CDKN1C gene. This protein is involved in the regulation… »
Cyclin-dependent kinase inhibitor 2A, isoform 4 (173 aa, ~18 kDa) is encoded by the human CDKN2A gene. This protein is involved in… »
Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (156 aa, ~17 kDa) is encoded by the human CDKN2A gene. This protein is involved in… »
Cyclin-dependent kinase inhibitor 3 (212 aa, ~24 kDa) is encoded by the human CDKN3 gene. This protein plays a role in the… »
The CDK Inhibitor Genes encode the CDK Inhibitor Proteins, a group of low molecular weight proteins that associate with cyclin-CDK complexes or… »
A protein that plays a role in the inhibition of cyclin-dependent kinases. »
Cyclin-dependent kinase-like 2 (493 aa, ~56 kDa) is encoded by the human CDKL2 gene. This protein is involved in protein phosphorylation and… »
Cyclin-dependent kinase-like 5 (1030 aa, ~116 kDa) is encoded by the human CDKL5 gene. This protein plays a role in protein… »
Cyclin-dependent kinases regulatory subunit 1 (79 aa, ~10 kDa) is encoded by the human CKS1B gene. This protein plays a role in… »
Cyclin-H (323 aa, ~38 kDa) is encoded by the human CCNH gene. This protein plays a role in both the mediation of… »
A centrally acting skeletal muscle relaxant with antidepressant activity. The exact mechanism of action of cyclobenzaprine has not been fully determined, but… »
A centrally acting muscle relaxant, chemically similar to amitriptyline hydrochloride with antidepressant activity. The exact mechanism of action of cyclobenzaprine hydrochloride has… »
A dimer consisting of two adjacent pyrimidines covalently jointed by a cyclobutane ring, inhibiting DNA replication. »
A formulation of camptothecin, an alkaloid isolated from the Chinese tree Camptotheca acuminata, conjugated with to a hydrophilic, cyclodextrin-based linear polymer with… »
A cyclic sulfonate ester with potential antineoplastic activity. As an alkylating agent, clyclodisone induces the formation of DNA interstrand crosslinks, DNA… »
A non-metabolizable synthetic amino acid, formed through the cyclization of the amino acid leucine, with immunosuppressive, antineoplastic, and cytostatic activities. Cycloleucine competitively… »
An enzyme that converts arachidonic acid into biologically active prostanoids, such as prostaglandins, prostacyclins, and thromboxanes. »
COX inhibitor. A type of drug that is used to treat inflammation and pain, and is being studied in the prevention and… »
Cyclooxygenase Interaction involves temporary non-covalent binding, typically through intermolecular physical forces of attraction and spatial complementarity, between a molecular entity and Cyclooxygenase,… »
An enzyme that speeds up the formation of substances that cause inflammation and pain. It may also cause tumor cells to… »
A nonsteroidal anti-inflammatory drug used to relieve pain and inflammation. Cyclooxygenase-2 inhibitors are being studied in the prevention of colon polyps, and… »
An aromatic hydrocarbon that consists of five fused rings and is formed during the incomplete combustion of organic matter. Cyclopenta[c,d]pyrene is primarily… »
A pro-drug carbocyclic analogue of cytidine with antineoplastic and antiviral activities. Cyclopentenyl cytosine (CPEC) is converted to the active metabolite cyclopentenyl cytosine… »
A benzothiadiazine sulfonamide derivative belonging to the class of the thiazide diuretics. »
The hydrochloride salt form of cyclopentolate, an anticholinergic drug. Administered in the eye, cyclopentolate hydrochloride blocks the acetylcholine receptor in the sphincter… »
A drug that is used to treat many types of cancer and is being studied in the treatment of other types of… »
The anhydrous form of cyclophosphamide, a synthetic nitrogen mustard alkylating agent, with antineoplastic and immunosuppressive activities. In the liver, cyclophosphamide is converted… »
A regimen consisting of cyclophosphamide and topotecan, used for the treatment of recurrent or refractory childhood Ewing's sarcoma. »
A regimen consisting of vincristine, doxorubicin and dexamethasone, used as induction treatment for multiple myeloma. »
A chemotherapy combination consisting of cyclophosphamide, doxorubicin, etoposide, mechlorethamine, methotrexate, prednisone, procarbazine, and vincristine. »
A combination antineoplastic therapy. »
A chemotherapy combination consisting of cyclophosphamide, mechlorethamine, prednisone, procarbazine, and vincristine. »
An analogue of the amino acid D-alanine with broad-spectrum antibiotic and glycinergic activities. D-cycloserine interferes with bacterial cell wall synthesis by… »
A drug used to help reduce the risk of rejection of organ and bone marrow transplants by the body. It is also… »
An topical ophthalmic formulation containing cyclosporine, an undecapeptide produced by the fungus Beauveria nivea, with immunosuppressant and anti-inflammatory activities. The exact therapeutic… »
A benzothiadiazide belonging to the class of thiazide diuretics. Cyclothiazide is indicated as adjunctive therapy in edema and in the treatment of… »
A member of the class of particle accelerator devices in which charged particles are accelerated electrically to high speeds while kept confined… »
A fragment of cytokeratin 19. A tumor marker. Reported to be a sensitive serum marker of recurrent breast cancer. … »
A gene transfer preparation of a plasmid DNA encoding mouse somatostatin receptor subtype 2 (sst2) and a fusion protein of human deoxycytidine… »
Human CYLD wild-type allele is located in the vicinity of 16q12.1 and is approximately 60 kb in length. This allele, which encodes… »
A surface formed by circles of a given radius that are contained in a plane perpendicular to a given axis, whose centers… »
Any part of a device that resembles an enclosed tube; a cylindrical container for the storage of gases and fluids. »
A dosing unit equal to the amount of active ingredient(s) contained in a cylinder. »
A valve designed to regulate the flow from a storage cylinder. »
A benign sweat gland neoplasm usually occurring in the scalp or the face. It may present as solitary or multiple papular or… »
Clonal proliferations arising from cutaneous hair follicles composed in part of cells with basaloid cytology that resemble human cylindromas. »
A drug used to treat depression and peripheral neuropathy (pain, numbness, tingling, burning, or weakness in the hands or feet) that can… »
The essential oil of Cymbopogon schoenanthus. Cymbopogon schoenanthus oil is used for its aromatic properties. »
A medium-sized macaque that tends to be an opportunistic omnivore, the Macaca fascicularis has grey-brown or reddish-brown fur that lightens ventrally, and… »
A macaque, Macaca fascicularis (M. cynomolgus), found mostly in southeastern Asia, Borneo, and the Philippines. »
This gene is involved in steroid metabolism. »
Human CYP11A1 wild-type allele is located within 15q23-q24 and is approximately 30 kb in length. This allele, which encodes cytochrome P450 11A1,… »
This gene plays a role in the metabolism of glucucorticoids. »
Human CYP11B1 wild-type allele is located within 8q21 and is approximately 7 kb in length. This allele, which encodes cytochrome P450 11B1,… »
This gene is involved in mineralocorticoid metabolism. »
Human CYP11B2 wild-type allele is located within 8q21-q22 and is approximately 7 kb in length. This allele, which encodes cytochrome P450 11B2,… »
An orally available inhibitor of the steroid 17-alpha-hydroxylase/C17,20 lyase (CYP17A1 or CYP17), with potential antiandrogen and antineoplastic activities. Upon oral administration, CYP17… »
This gene plays a role in the metabolism of estrogen and glucocorticoids. It is also involved in sexual maturation. »
Human CYP17A1 wild-type allele is located in the vicinity of 10q24.3 and is approximately 7 kb in length. This allele, which encodes… »
This gene is involved in development and estrogen metabolism. »
Human CYP19A1 wild-type allele is located in the vicinity of 15q21.1 and is approximately 114 kb in length. This allele, which encodes… »
This gene plays a role in the oxidation of procarcinogens. This process activates these compounds to carcinogens. »
Human CYP1A1 wild-type allele is located within 15q22-q24 and is approximately 6 kb in length. This allele, which encodes cytochrome P450 1A1… »
This gene plays a role in the oxidation/activation of procarcinogens. It is also involved in the metabolism of drugs and other… »
Human CYP1A2 wild-type allele is located within 15q24 and is approximately 8 kb in length. This allele, which encodes cytochrome P450 1A2… »
Human CYP1A2*1 allele is located within 15q24 and is approximately 8 kb in length. This allele, a variant form of the CYP1A2… »
Human CYP1A2*11 allele is located within 15q24 and is approximately 8 kb in length. This allele, a variant form of the CYP1A2… »
Human CYP1A2*7 allele is located within 15q24 and is approximately 8 kb in length. This allele, a variant form of the CYP1A2… »
This gene plays a role in eye development, steroid catabolism and xenobiotic metabolism. »
Human CYP1B1 wild-type allele is located in the vicinity of 2p22.2 and is approximately 43 kb in length. This allele, which encodes… »
This gene plays a role in steroid metabolism. »
Human CYP21A2 wild-type allele is located in the vicinity of 6p21.3 and is approximately 3 kb in length. This allele, which encodes… »
This gene plays a role in vitamin D3 metabolism and calcium homeostasis. »
Human CYP24A1 wild-type allele is located within 20q13.2-q13.3 and is approximately 21 kb in length. This allele, which encodes 1,25-dihydroxyvitamin D(3) 24-hydroxylase,… »
This gene plays a role in the metabolism of retinoic acid. »
Human CYP26B1 wild-type allele is located in the vicinity of 2p13.2 and is approximately 19 kb in length. This allele, which encodes… »
This gene is involved in cholesterol homeostasis and bile synthesis. »
Human CYP27A1 wild-type allele is located within 2q33-qter and is approximately 34 kb in length. This allele, which encodes sterol 26-hydroxylase, mitochondrial… »
This gene is involved in vitamin D metabolism and calcium homeostasis. »
Human CYP27B1 wild-type allele is located within 12q13.1-q13.3 and is approximately 5 kb in length. This allele, which encodes 25-hydroxyvitamin D-1 alpha… »
This gene plays a role in the oxidation of nicotine to its carcinogenic metabolites. »
Human CYP2A6 wild-type allele is located in the vicinity of 19q13.2 and is approximately 7 kb in length. This allele, which encodes… »
This gene is involved in the oxidation of both endogenous substrates and drugs/xenobiotics. »
Human CYP2B6 wild-type allele is located in the vicinity of 19q13.2 and is approximately 27 kb in length. This allele, which encodes… »
This gene plays a role in the metabolism of fatty acids, tryptophan, drugs and xenobiotics. »
Human CYP2C18 wild-type allele is located within 10q24 and is approximately 53 kb in length. This allele, which encodes cytochrome P450 2C18… »
This gene is involved in the metabolism of drugs and xenobiotics. »
Human CYP2C19 wild-type allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, which encodes cytochrome P450 2C19… »
Human CYP2C19*1 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19… »
Human CYP2C19*10 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19… »
Human CYP2C19*12 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19… »
Human CYP2C19*2 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19… »
Human CYP2C19*3 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19… »
Human CYP2C19*4 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19… »
Human CYP2C19*5 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19… »
Human CYP2C19*6 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19… »
Human CYP2C19*7 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19… »
Human CYP2C19*8 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19… »
Human CYP2C19*9 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19… »
This gene plays a role in drug metabolism. It is also involved in the oxidation of both endobiotics and xenobiotics. »
Human CYP2C8 wild-type allele is located in the vicinity of 10q23.33 and is approximately 33 kb in length. This allele, which encodes… »
Human CYP2C8*2 allele is located in the vicinity of 10q23.33 and is approximately 33 kb in length. This allele, a variant form… »
Human CYP2C8*3 allele is located in the vicinity of 10q23.33 and is approximately 33 kb in length. This allele, a variant form… »
Human CYP2C8*4 allele is located in the vicinity of 10q23.33 and is approximately 33 kb in length. This allele, a variant form… »
Human CYP2C8*5 allele is located in the vicinity of 10q23.33 and is approximately 33 kb in length. This allele, a variant form… »
Human CYP2C8*6 allele is located in the vicinity of 10q23.33 and is approximately 33 kb in length. This allele, a variant form… »
Human CYP2C8*7 allele is located in the vicinity of 10q23.33 and is approximately 33 kb in length. This allele, a variant form… »
Human CYP2C8*8 allele is located in the vicinity of 10q23.33 and is approximately 33 kb in length. This allele, a variant form… »
This gene is involved in the oxidation of drugs, xenobiotics, fatty acids and steroids. »
Human CYP2C9 wild-type allele is located within 10q24 and is approximately 33 kb in length. This allele, which encodes cytochrome P450 2C9… »
Human CYP2C9*1 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9… »
Human CYP2C9*11 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9… »
Human CYP2C9*12 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9… »
Human CYP2C9*16 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9… »
Human CYP2C9*18 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9… »
Human CYP2C9*2 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9… »
Human CYP2C9*3 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9… »
Human CYP2C9*5 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9… »
Human CYP2C9*6 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9… »
Human CYP2C9*8 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9… »
This gene plays a role in the metabolism of numerous clinically-relevant drugs. It is also involved in the oxidation of xenobiotics. … »
Human CYP2D6 wild-type allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, which encodes… »
Human CYP2D6*1 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*10 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*11 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*12 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*13 allele, located in the vicinity of 22q13.1, is a variant form of the CYP2D6 wild-type allele and encodes cytochrome P450… »
Human CYP2D6*14 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*15 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*16 allele, located in the vicinity of 22q13.1, is a variant form of the CYP2D6 wild-type allele and encodes cytochrome P450… »
Human CYP2D6*17 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*18 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*19 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*2 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*20 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. The CYP2D6*20 allele, a variant… »
Human CYP2D6*21 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*2N allele, a variant form of the CYP2D6 wild-type allele, is approximately 4 kb in length and encodes cytochrome P450 2D6… »
Human CYP2D6*3 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*35X2 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, an amplification variant… »
Human CYP2D6*36 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*38 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*4 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*40 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*41 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*42 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*44 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*5 allele is a variant form of the CYP2D6 wild-type allele. The CYP2D6*5 allele is a result of deletion of the… »
Human CYP2D6*6 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*7 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*8 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
Human CYP2D6*9 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form… »
This gene is involved in the metabolism of both endogenous and exogenous substrates. »
Human CYP2E1 wild-type allele is located within 10q24.3-qter and is approximately 12 kb in length. This allele, which encodes cytochrome P4502E1 protein,… »
Human CYP2E1*1 allele is located within 10q24.3-qter and is approximately 12 kb in length. This allele, a variant form of the CYP2E1… »
Human CYP2E1*2 allele is located within 10q24.3-qter and is approximately 12 kb in length. This allele, a variant form of the CYP2E1… »
Human CYP3A gene locus is located within 7q21.3-q22.1 and is approximately 218 kb in length. This locus includes four protein-encoding genes, CYP3A4,… »
This gene plays an role in the metabolism of numerous clinically-relevant drugs. It is also involved in the oxidation of both endogenous… »
Human CYP3A4 wild-type allele is located in the vicinity of 7q21.1 and is approximately 27 kb in length. This allele, which encodes… »
Human CYP3A4*17 allele is located in the vicinity of 7q21.1 and is approximately 27 kb in length. This allele, a variant form… »
Human CYP3A4*18 allele is located in the vicinity of 7q21.1 and is approximately 27 kb in length. This allele, a variant form… »
This gene is involved in the metabolism of fatty acids, steroids, drugs and xenobiotics. It also plays a role in the metabolism… »
Human CYP3A5 wild-type allele is located in the vicinity of 7q21.1 and is approximately 32 kb in length. This allele, which encodes… »
Human CYP3A5*10 allele is located in the vicinity of 7q21.1 and is approximately 32 kb in length. This allele, a variant form… »
Human CYP3A5*3 allele is located in the vicinity of 7q21.1 and is approximately 32 kb in length. This allele, a variant form… »
Human CYP3A5*6 allele is located in the vicinity of 7q21.1 and is approximately 32 kb in length. This allele, a variant form… »
Human CYP3A5*8 allele is located in the vicinity of 7q21.1 and is approximately 32 kb in length. This allele, a variant form… »
Human CYP3A5*9 allele is located in the vicinity of 7q21.1 and is approximately 32 kb in length. This allele, a variant form… »
This gene plays a role in the metabolism of drugs, xenobiotics, fatty acids and steroids. It is also involved in the synthesis… »
Human CYP3A7 wild-type allele is located within 7q21-q22.1 and is approximately 30 kb in length. This allele, which encodes cytochrome P450 3A7… »
Human CYP3A7*2 allele is located within 7q21-q22.1 and is approximately 30 kb in length. This allele, a variant form of the human… »
This gene is involved in bile acid synthesis and steroid metabolism. »
Human CYP7A1 wild-type allele is located within 8q11-q12 and is approximately 10 kb in length. This allele, which encodes cytochrome P450 7A1… »
This gene plays a role in steroid metabolism and regulation of cholesterol solubility. »
Human CYP8B1 wild-type allele is located within 3p22-p21.3 and is approximately 4 kb in length. This allele, which encodes cytochrome P450 8B1… »
A drug that is used to treat asthma, allergies, and colds, and to relieve itching caused by certain skin disorders. It has… »
The hydrochloride salt of a synthetic methyl-piperidine derivative with antihistaminic and anti-serotoninergic properties. Cyproheptadine competes with free histamine (HA) for binding… »
A synthetic steroidal anti-androgen with antineoplastic activity. Cyproterone, in its acetate form, binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation… »
A synthetic hormone being studied for treatment of hot flashes in men with prostate cancer who have had both testicles removed by… »
This gene plays a role in apoptosis, angiogenesis, heart development and many other processes. »
Human CYR61 wild-type allele is located in the vicinity of 1p22.3 and is approximately 3 kb in length. This allele, which encodes… »
A drug used with other drugs to treat colorectal cancer and non-small cell lung cancer that have spread to other parts of… »
A closed, sac-like pocket of tissue that can form anywhere in the body. It may be filled with fluid, air, pus, or… »
A morphologic finding indicating the presence of cystic structures in a tissue sample. »
A malignant cystic epithelial neoplasm arising from the glandular epithelium. The malignant epithelial cells invade the stroma. The cystic spaces… »
A benign or borderline neoplasm that arises from the ovaries and the fallopian tubes. It is characterized by the presence of cystic… »
A benign or borderline cystic epithelial neoplasm arising from the glandular epithelium. The epithelial cells line the cystic spaces which contain… »
The determination of the amount of cystatin C present in a sample. »
The determination of the ratio of cystatin C compared to creatinine present in a sample. The measurement may be expressed as a… »
Cystatin Family Genes encode (Type 2) Cystatin proteins, secreted, tight, reversible, competitive inhibitors of cysteine proteinases that contain multiple cystatin-like sequences and… »
Cystatin Superfamily Genes comprise a single evolutionary superfamily that encode protein subfamilies with functional and structural similarities that include cystatin-like sequences: Stefins… »
Cystatin-C (146 aa, ~16 kDa) is encoded by the human CST3 gene. This protein is involved in the inhibition of cysteine… »
Cystatin-M (149 aa, ~17 kDa) is encoded by the human CST6 gene. This protein plays a role in the modulation of cathepsin… »
An aminothiol salt used in the treatment of nephropathic cystinosis. Cysteamine bitartrate enters the cell and reacts with cystine producing cysteine and… »
Surgery to remove all or part of the bladder (the organ that holds urine) or to remove a cyst (a sac or… »
A non-essential sulfur-containing amino acid in humans, related to cystine, Cysteine is important for protein synthesis, detoxification, and diverse metabolic functions. Found… »
Cysteine Protease Genes encode endopeptidases, inactivated by sulfhydryl reagents, that have a cysteine residue involved in the catalytic process. »
An enzyme that contains an unpaired cysteine in the active site which acts as a nucleophilic thiol to catalyze the proteolytic processing… »
Human Cysteine Proteinase Inhibitor Genes encode Cysteine Proteinase Inhibitors, endogenous proteins that hinder the function of cysteine proteinases. »
The Cysteine-Rich Domain is usually found in two copies per protein. It contains up to four conserved cysteines. The family includes a… »
Cysteine-rich hydrophobic domain 2 protein (165 aa, ~19 kDa) is encoded by the human CHIC2 gene. This protein may play a role… »
A biologically active, cysteine-rich, undenatured, bovine whey-based protein isolate with potential anti-cachexia and glutathione-enhancing properties. Upon administration of cysteine-rich whey protein isolate,… »
Cysteine-rich protein 2 (208 aa, ~22 kDa) is encoded by the human CRIP2 gene. This putative transcription factor may play a role… »
Cysteinyl-tRNA synthetase, cytoplasmic (748 aa, ~85 kDa) is encoded by the human CARS gene. This protein is involved in tRNA aminoacylation. … »
A chloroethylating nitrosourea that causes DNA cross-linking, inhibiting DNA replication. »
A microscopic finding indicating the formation of cystic structures in a tissue sample. »
A tube that carries bile from the gall bladder. It joins the common hepatic duct to form the common bile duct. It… »
Benign endometrial hyperplasia characterized by the presence of cystically dilated glands. »
A common hereditary disease in which exocrine (secretory) glands produce abnormally thick mucus. This mucus can cause problems in digestion, breathing, and… »
A genetic test to determine if either parent has the trait of cystic fibrosis carrier. »
Cystic fibrosis transmembrane conductance regulator (1480 aa, ~168 kDa) is encoded by the human CFTR gene. This protein is involved in chloride… »
A congenital metabolic detected in the neonatal period that is characterized by the presence of a meconium ileus. The disease affects the… »
A benign lymphatic neoplasm usually arising from the neck and characterized by cystic dilation of the lymphatic vessels. »
A cystic lesion with a central keratin mass which is surrounded by squamous epithelium. »
A congenital or acquired kidney disorder characterized by the presence of renal cysts. »
An idiopathic disorder characterized by the degeneration of the aortic media tissue and formation of cyst-like spaces. It may lead to aortic… »
MIN NOS that forms cystic structures filled with fluid. »
A benign encapsulated neoplasm of the kidney, characterized by the presence of cysts separated by septa. There are no solid areas… »
An oncocytoma with cystic degenerative changes. »
A variant of Wilm tumor of the kidney characterized by the presence of cystic spaces separated by septa. The septa contain… »
Necrosis and softening of the white matter around the ventricles in the brain associated with cystic changes. »
A multicystic tumor arising in the inferior interatrial septum in the region of the atrioventricular node. The vast majority of patients present… »
A blood vessel carrying deoxygenated blood from the gallbladder and the cystic duct into the right branch of the portal vein. … »
A parasitic infection caused by the larval form of Taenia solium. It is a disseminated infection affecting the central nervous system, subcutaneous… »
Not considered one of the 20 amino acids, Cystine is a sulfur-containing derivative obtained from oxidation of cysteine amino acid thiol side… »
The determination of the amount of cystine crystals present in a sample. »
The determination of the amount of cystine present in a sample. »
Cystine/glutamate transporter protein (501aa, ~55 kDa) is encoded by the human SLC7A11 gene. This protein is involved in the exchange of anionic… »
An autosomal recessive hereditary disorder characterized by defective transportation of cystine across the lysosomal membranes and systemic deposition of cystine crystals in… »
An autosomal recessive inherited metabolic disorder caused by mutations in the SLC3A1 and SLC7A9 genes. It is characterized by deficient re-absorption of… »
A reactive inflammatory disorder affecting the bladder. It is characterized by the development of small cysts in the bladder wall. The cysts… »
A reactive inflammatory disorder affecting the bladder. It is characterized by the development of small cysts in the bladder wall. … »
A reactive inflammatory disorder affecting the bladder. It is characterized by the development of small cysts in the bladder wall. … »
A radiographic procedure to obtain an image of the urinary bladder by filling the bladder with contrast medium. »
Macular degeneration characterized by edema and cystic spaces which may lead to a macular depression or hole. »
Surgery to remove the bladder (the organ that holds urine) and the prostate. In a radical cystoprostatectomy, the seminal vesicles are also… »
A type of tumor found in breast or prostate tissue. It is often large and bulky and grows quickly. It may be… »
A thin, tube-like instrument used to look inside the bladder and urethra. A cystoscope has a light and a lens for viewing… »
Examination of the bladder and urethra using a cystoscope, inserted into the urethra. A cystoscope is a thin, tube-like instrument with a… »
Surgical creation of an opening (stoma) for drainage of the urinary bladder. »
Surgery to remove the bladder (the organ that holds urine) and urethra (the tube through which urine leaves the body). »
A drug used to treat certain types of leukemia and prevent the spread of leukemia to the meninges (three thin layers of… »
The hydrochloride form of cytarabine, an antimetabolite analogue of cytidine with a modified sugar moiety (arabinose instead of ribose). Cytarabine is converted… »
A form of the anticancer drug cytarabine that is contained inside very tiny, fat-like particles. It may have fewer side effects and… »
A regimen consisting of cytarabine and daunorubicin used as both as induction and consolidation (post remission) treatment for acute myeloid leukemia. … »
A regimen consisting of cytarabine, daunorubicn, and etoposide used as an induction regimen for the treatment of acute myeloid leukemia. »
A regimen consisting of cytarabine and idarubicin used as both an induction and consolidation (post remission) treatment for acute myeloid leukemia. … »
A regimen consisting of cytarabine and mitoxantrone used as both induction and consolidation (post remission) treatment for acute myeloid leukemia. This regimen… »
A regimen consisting of cytarabine and thioguanine used as post remission maintenance treatment for acute myeloid leukemia. Was originally used as an… »
A pyrimidine nucleoside that is composed of the base cytosine linked to the five-carbon sugar D-ribose. »
An orally available small molecule and nucleoside antimetabolite with potential antineoplastic activity. Upon administration, the cytidine analog RX-3117 is taken up by… »
Cytidine deaminase (146 aa, ~16 kDa) is encoded by the human CDA gene. This protein is involved in the deamination of cytidine… »
Any substance that inhibits cytidine deaminase, an enzyme that scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. Inhibition of cytidine… »
Any substance that inhibits cytidine triphosphate synthetase, an enzyme that catalyses the rate-limiting step in the synthesis of CTP. Inhibition of cytidine… »
A family of enzymes that catalyze the transfer of a phosphate group using CTP as the donor molecule (EC 2.7.7.x) »
Branch of histochemistry associated with the localization of cellular components by specific staining methods, as for example the localization of acid phosphatases… »
A substance being studied in the treatment of cancer that has spread to the brain. It has also been studied in the… »
A family of membrane-associated, heme-containing proteins that catalyze oxidation and reduction to promote electron transport reactions. »
Cytochrome B-245 heavy chain (570 aa, ~65 kDa) is encoded by the human CYBB gene. This protein plays a role in the… »
Cytochrome b-c1 complex subunit 6, mitochondrial (91 aa, ~11 kDa) is encoded by the human UQCRH gene. This protein plays a role… »
An enzyme complex that plays a role in the electron transport cascade leading to ATP synthesis. »
Cytochrome c oxidase assembly protein COX11, mitochondrial (276 aa, ~31 kDa) is encoded by the human COX11 gene. This protein is involved… »
Cytochrome c oxidase subunit 6C (75 aa, ~9 kDa) is encoded by the human COX6C gene. This protein is involved in electron… »
Cytochrome c oxidase subunit 7A-related protein, mitochondrial (114 aa, ~13 kDa) is encoded by the human COX7A2L gene. This protein is involved… »
Cytochrome c-type heme lyase (268 aa, ~31 kDa) is encoded by the human HCCS gene. This protein is involved in the production… »
A family of cytochromes that are involved in electron transport and oxidative metabolism of drugs and other bioactive molecules. When the catalytic… »
Cytochrome P450 11B2, mitochondrial (503 aa, ~58 kDa) is encoded by the human CYP11B2 gene. This protein plays a role in corticosterone… »
Cytochrome P450 19A1 (503 aa, ~58 kDa) is encoded by the human CYP19A1 gene. This protein is involved in the conversion of… »
Cytochrome P450 1A1 (512 aa, ~58 kDa) is encoded by the human CYP1A1 gene. This protein is involved in the metabolism of… »
Cytochrome P450 1A2 (515 aa, ~58 kDa) is encoded by the human CYP1A2 gene. This protein is involved in the hydroxylation of… »
Cytochrome P450 1B1 (543 aa, ~61 kDa) is encoded by the human CYP1B1 gene. This protein plays a role in the metabolism… »
Cytochrome P450 26B1 (512 aa, ~58 kDa) is encoded by the human CYP26B1 gene. This protein plays a role in the metabolism… »
Mouse cytochrome P450 2a5 protein (494 aa, 57 kD) is encoded by the mouse Cyp2a5 gene. This enzyme is an unspecific, membrane-bound,… »
Cytochrome P450 2A6 (494 aa, ~57 kDa) is encoded by the human CYP2A6 gene. This protein is involved in the metabolism of… »
Cytochrome P450 2B6 (491 aa, ~56 kDa) is encoded by the human CYP2B6 gene. This protein plays a role in the metabolism… »
Cytochrome P450 2C18 (490 aa, ~56 kDa) is encoded by the human CYP2C18 gene. This protein plays a role in the electron… »
Cytochrome P450 2C19 (490 aa, ~56 kDa) is encoded by the human CYP2C19 gene. This protein is involved in steroid, terpenoid and… »
Cytochrome P450 2C8 (490 aa, ~56 kDa) is encoded by the human CYP2C8 gene. This protein is involved in the oxidation of… »
Cytochrome P450 2C9 (490 aa, ~56 kDa) is encoded by the human CYP2C9 gene. This protein is involved in the oxidation of… »
Cytochrome P450 2D5 is a rat liver ER membrane-bound heme-thiolate monooxygenase, involved in an NADPH-dependent electron transport pathway that oxidizes various compounds,… »
Cytochrome P450 2D6 (497 aa, ~56 kDa) is encoded by the human CYP2D6 gene. This protein plays a role in flavoprotein… »
Cytochrome P450 2E1 (493 aa, ~57 kDa) is encoded by the human CYP2E1 gene. This protein plays a role in the both… »
Cytochrome P450 3A4 (503 aa, ~57 kDa) is encoded by the human CYP3A4 gene. This protein is involved in the oxidation of… »
Any substance that induces the activity of the liver enzyme cytochrome P450 3A4. By inducing the activity of the CYP3A4 enzyme, the… »
Any substance that inhibits the activity of the liver enzyme cytochrome P450 3A4. By inhibiting the activity of the CYP3A4 enzyme, the… »
Cytochrome P450 3A5 (502 aa, ~57 kDa) is encoded by the human CYP3A5 gene. This protein is involved in the oxidation of… »
Cytochrome P450 3A7 (503 aa, ~58 kDa) is encoded by the human CYP3A7 gene. This protein plays a role in the oxidation… »
Cytochrome P450 CYP11B1, mitochondrial (503 aa, ~58 kDa) is encoded by the human CYP11B1 gene. This protein plays a role in steroid… »
A group of enzymes involved in drug metabolism and found in high levels in the liver. These enzymes change many drugs, including… »
Cytochrome P450 Family Genes encode Cytochrome P450 isozymes, hemoprotein components of the mixed-function oxidase system involving electron and/or hydrogen transport through reversible… »
A very rare inherited metabolic disorder characterized by deficiency of the enzyme cytochrome-C oxidase. It may be manifested as an isolated myopathy… »
An irregularity in the number or structure of chromosomes, usually in the form of a gain (duplication), loss (deletion), exchange (translocation), or… »
Techniques for analysis of chromosomal and subchromosomal properties and structures, such as those to diagnose, classify, screen for, or manage genetic diseases… »
The visual appearance of a chromosome when stained and examined under a microscope. Particularly important are visually distinct regions, called light and… »
The study of chromosomes and chromosomal abnormalities. »
Cytogenetics Shared Resource provides Cancer Center members with support in following areas: routine cytogenetic (such as giemsa (G)-banding on fibroblast, lymphoblast or… »
A type of protein found on epithelial cells, which line the inside and outside surfaces of the body. Cytokeratins help form the… »
A protein often found as a cell surface marker on tumor cells. »
An immunohistochemical diagnostic test utilizing an antibody to detect both cytokeratin 5 and 6 in tissues. »
The determination of the amount of the cytokeratin 19 fragment 21-1 present in a sample. »
An immunohistochemical technique to detect cytokeratin14,an intermediate filament protein, using monoclonal antibody to cytokeratin 14. The technique is used in diagnostic histopathology… »
An immunohistochemical technique to detect cytokeratin 18, an intermediate filament protein, using monoclonal antibody to cytokeratin 18. Specific combinations of cytokeratin peptides… »
An immunohistochemical technique to detect cytokeratin 8, an intermediate filament protein, using monoclonal antibody to cytokeratin 8. The antibody is useful in… »
A type of protein that is made by certain immune and non-immune cells and has an effect on the immune system. Some… »
Cytokine Degradation consists of conjugation, transport, oxidation, and/or proteolysis of a class of soluble non-antibody paracrine or autocrine signaling glycoproteins (cytokines) secreted… »
Cytokines are soluble glycoproteins released by cells of the immune system, which act nonenzymatically through specific receptors to regulate immune responses. Cytokines… »
The determination of type and amount of cytokines in a sample. »
Several different cell types coordinate their efforts as part of the immune system, including B cells, T cells, macrophages, neutrophils, basophils and… »
An assay to detect the presence and level of 12 cytokines in a blood sample (IFN gamma, IL1 beta, IL10, IL12, IL13,… »
A cytokine receptor is a protein on the cell surface that specifically binds cytokine ligands which are small proteins secreted by immune… »
Any interaction between a cognate ligand and any of a series of cytokine receptors. Activation of cytokine receptors is involved in regulation… »
A process that involves the binding of any member of the cytokine family to a cognate cytokine receptor. These interactions are involved… »
Cytokine Receptor Genes encode cell surface Cytokine Receptors that bind paracrine or autocrine cytokine growth factors that stimulate humoral and cellular immune… »
Cytokine receptor-like factor 1 (422 aa, ~46 kDa) is encoded by the human CRLF1 gene. This protein may be involved in both… »
Cytokine receptor-like factor 2 (371 aa, ~42 kDa) is encoded by the human CRLF2 gene. This protein is involved in the mediation… »
A syndrome that occurs after therapeutic infusion of antibodies into the blood and is characterized by nausea, headache, tachycardia, hypotension, rash, and… »
Any environment-to-cell cummunication that involves cytokines. This process is involved in immune function. »
Any process which promotes expression of cytokine proteins, their subsequent secretion, binding to their cognate receptors or intracellular signaling, and results in… »
Any therapeutic or preventive precedure that involves inhibition of the production or activity of a cytokine, and results in the inhibition of… »
Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as… »
A preparation of autologous lymphocytes with potential immunopotentiating and antineoplastic activities. Cytokine-induced killer (CIK) cells are CD3- and CD56-positive, non-major histocompatibility complex… »
Cytokine-inducible SH2-containing protein (258 aa, ~29 kDa) is encoded by the human CISH gene. This protein is involved in the modulation of… »
Process in which the cytoplasm of a cell is divided after nuclear division (mitosis) is complete. »
A diagnostic test utilized to examine and define cellular anatomy or function. The test results are often used by a clinician to… »
Technique or procedure for manipulation of cells and analysis of cell properties and subcellular features. »
Any cell death process resulting from rupture of cell membranes and loss of cytoplasm. »
An abnormal cell that contains intranuclear and intracytoplasmic cytomegalovirus inclusion bodies. »
A herpesvirus infection caused by Cytomegalovirus. Healthy individuals generally do not produce symptoms. However, the infection may be life-threatening in affected immunocompromised… »
A virus that may be carried in an inactive state for life by healthy individuals. It is a cause of severe pneumonia… »
Cytotoxic T-lymphocytes (CTLs), specifically reactive to the cytomegalovirus (CMV) immediate early-1 (IE-1) protein, with immunomodulating activity. Adoptive immunotherapy with cytomegalovirus IE-1-specific cytotoxic… »
The determination of the amount of cytomegalovirus IgG antibody present in a sample. »
The determination of the amount of cytomegalovirus IgM antibody present in a sample. »
Cytomegalovirus (CMV) is a virus found around the world. It is related to the viruses that cause chickenpox and infectious mononucleosis… »
Cytotoxic T lymphocytes (CTLs) specifically reactive to the cytomegalovirus (CMV) phosphoprotein pp65 with potential antiviral activity. To prepare CMV pp65-specific cytotoxic T… »
The determination of the amount of cytomegalovirus viral load present in a sample. »
A drug that is used to treat certain thyroid (a gland located near the voice box) conditions. It is also being studied… »
The measurement of physical and /or chemical characteristics of cells, or, by extension, of other biological particles. »
A branch of pathology that studies and diagnoses diseases on the cellular level including the anatomy, physiology, pathology and chemistry of the… »
Without morphologic dysgranulopoiesis, dyserythropoiesis, or dysplastic megakaryocytes; greater or equal to 20% myeloid immature forms/blasts in bone marrow and/or spleen »
The fluid inside a cell but outside the cell's nucleus. Most chemical reactions in a cell take place in the cytoplasm. … »
A morphologic finding indicating the presence of less than or equal to twenty five percent of clear or vacuolated cells that resemble… »
The determination of the amount of neutrophils in a biological specimen showing a dark staining pattern in the cytoplasm due to increased… »
The part of a transmembrane protein which projects into the cytoplasm. »
A stainable aggregation of protein, lipid or small molecules in the cytoplasm. »
A fluid cytoplasmic substance filling the interstices of the cytoskeleton. »
Cell part which consists of macromolecules aggregated into discrete structures in the protoplasm. (Digital Anatomist Foundational Model) »
Cytoplasmic phosphatidylinositol transfer protein 1 (332 aa, ~38 kDa) is encoded by the human PITPNC1 gene. This protein plays a role in… »
Protein within the interior of the cell; excludes membrane, mitochondrial, and nuclear proteins. »
Cytoplasmic Protein Genes encode Cytoplasmic Proteins that are typically localized in the cell interior, generally excluding the plasma membrane, mitochondria, and the… »
Cytoplasmic Receptors are selective binding proteins that mediate the physiologic effects of specific bound regulatory molecules, such as hormones that cause a… »
RNA present in the cytoplasm. It is involved in the protein export process from the cells. »
Cytoplasmic tyrosine-protein kinase BMX (675 aa, ~78 kDa) is encoded by the human BMX gene. This protein is involved in protein phosphorylation,… »
A morphologic finding referring to the presence of vacuoles within the cytoplasm of the cells. »
Agents administered before, with, or after cancer therapy to reduce or prevent damage or toxicity to the normal cells. »
A chemical compound that is used to make one of the building blocks of DNA and RNA. It is a type of… »
A point mutation involving the substitution of Adenosine (a purine base) for Cytosine (a pyrimidine base) in a DNA sequence from eukaryotic… »
A point mutation involving the substitution of Guanosine (a purine base) for Cytosine (a pyrimidine base) in a DNA sequence from eukaryotic… »
A point mutation involving the substitution of Thymidine (a pyrimidine base) for Cytosine (a pyrimidine base) in a DNA sequence from eukaryotic… »
Cytoskeletal Genes encode Cytoskeletal Proteins, diverse structural proteins including polymerizable globular subunits (actin, tubulin), "motor ATPases" (myosin, dynein), membrane-supporting linkers (spectrin, clathrin),… »
Subcellular biological functions, activities, or processes that generate, maintain, or modify macromolecular cytoskeletal components. »
Any process that takes place on the cellular level, and which results in the assembly or disassembly of cytoskeletal structures or the… »
Major constituent of the cytoskeleton found in the cytoplasm of eukaryotic cells. They form a flexible framework for the cell, provide attachment… »
Cytoskeletal Synthesis Inhibition consists of interference with, or restraint of, the activities of enzymes involved in the formation of the protein scaffolding… »
The protein scaffolding (the network of filaments microfilaments, microtubules, intermediate filaments, and their associated proteins) that gives shape, structure, and organization to… »
A group of three types of polymeric protein structures that impart shape to a cell and are involved in cellular motility, organelle… »
The study of the role of the cytoskeleton in the development and treatment of tumors and cancer. »
The aqueous part of the cytoplasm within which various particles and organelles are suspended. »
Specific families of pattern recognition receptors are responsible for detecting foreign DNA from invading microbes or host cells and generating innate immune… »
Cytosolic phospholipase A2 (749 aa, ~85 kDa) is encoded by the human PLA2G4A gene. This protein is involved in arachidonic acid… »
Cytosolic phospholipase A2 beta (781 aa, ~88 kDa) is encoded by the human PLA2G4B gene. This protein plays a role in glycerophospholipid… »
Cytosolic phospholipase A2 delta (818 aa, ~92 kDa) is encoded by the human PLA2G4D gene. This protein plays a role in phospholipid… »
Cytosolic phospholipase A2 gamma (541 aa, ~61 kDa) is encoded by the human PLA2G4C gene. This protein is involved in phospholipid… »
A family of cytosolic enzymes that are involved in the calcium-dependent hydrolysis of phospholipids. »
Cytosolic purine 5'-nucleotidase (561 aa, ~65 kDa) is encoded by the human NT5C2 gene. This protein plays a role in the maintenance… »
Cytospin-B (1068 aa, ~119 kDa) is encoded by the human SPECC1 gene. This protein may be involved in the structure of the… »
A substance that slows or stops the growth of cells, including cancer cells, without killing them. These agents may cause tumors to… »
A substance that kills cells, including cancer cells. These agents may stop cancer cells from dividing and growing and may cause tumors… »
Cytotoxic and regulatory T-cell molecule (393 aa, ~47 kDa) is encoded by the human CRTAM gene. This protein is involved in promoting… »
Anticancer drugs that kill cells, especially cancer cells. »
A type of immune cell that can kill certain cells, including foreign cells, cancer cells, and cells infected with a virus. Cytotoxic… »
Cytotoxic T cells are a key part of the cellular immune response, killing cells that display foreign antigen on their surface, primarily… »
A type of immune cell that can kill certain cells, including foreign cells, cancer cells, and cells infected with a virus. Cytotoxic… »
Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC),… »
CTLA-4 is an inhibitory T-cell surface receptor for B7 ligands on antigen presenting cells. It contains an extracellular V-like domain, a transmembrane… »
The adverse effect of some iatrogenic therapies. It is an accepted side effect in radiation therapy where the desired effect is to… »
A polygonal, mononucleate cell resembling the cells of the inner layer of the trophoblast, having prominent nucleoli and clear, eosinophilic or basophilic… »
A drug that is used to treat many types of cancer and is being studied in the treatment of other types of… »
A regimen consisting of cyclophosphamide, vincristine, doxorubicin, and dacarbazine used for the treatment of unresectable soft-tissue sarcoma. »
A country in central Europe, southeast of Germany and southwest of Poland. »
A unit of potency of poliovirus vaccine used for poliomyelitis prevention. The unit is poliovirus type-specific. »
A unit of potency of poliovirus vaccine expressed as a number of D antigen units per one milliliter of vaccine formulation. … »
A family of lipo-soluble steroids important to the absorption, metabolism, and function of calcium and phosphorus and the growth and development of… »
A substance being studied in the treatment of melanoma and many other types of cancer. D-1MT blocks the breakdown of the amino… »
A synthetic luteinizing hormone-releasing hormone (LH-RH) antagonist that suppresses LH and sex steroid levels. »
D-3-phosphoglycerate dehydrogenase (533 aa, ~57 kDa) is encoded by the human PHGDH gene. This protein plays a role in the serine biosynthesis… »
A naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties. Considered essential for the stabilization of biological membranes… »
A drug used to treat tuberculosis. It is also being studied in the treatment of pain and nerve problems (numbness, tingling) caused… »
The determination of the amount of d-dimers present in a sample. »
A proprietary oral formulation of D-methionine with antioxidant and antimucositis activities. D-methionine formulation MRX-1024 may selectively protect the oral mucosa from the… »
The synthetic dextro isomer of phenylalanine, an essential amino acid with anti-depressant and analgesic activities. D-Phenylalanine is converted into tyrosine and tyrosine… »
A non-essential amino acid and dextro isomer of serine with antipsychotic activity. D-serine is a selective full agonist at the glycine site… »
A procedure to remove tissue from the cervical canal or the inner lining of the uterus. The cervix is dilated (made larger)… »
A recombinant, chimeric protein derived from a melanoma antigenic epitope (MAGE-3) and recognized by specific cytotoxic T lymphocytes. MAGE-3, a human… »
The H4 gene is found fused to the RET Gene in papillary thyroid carcinoma and to platelet-derived growth factor receptor betaR in… »
A dinucleotide repeat on chromosome 17 that serves as a marker for microsatellite instability in colorectal cancers. »
A dinucleotide repeat on chromosome 2 that serves as a marker for microsatellite instability in colorectal cancers. »
D4-GDP dissociation inhibitor (D4-GDI) is a negative regulator of the ras related Rho Family of GTPases. Since the rho GTPases promote cytoskeletal… »
A dinucleotide repeat on chromosome 5 that serves as a marker for microsatellite instability in colorectal cancers. »
The root of this plant has been used in some cultures to treat certain medical problems. It may have anti-inflammatory and anticancer… »
DA: Urinary bladder tumors 54% in males and 14% in females, with a peak incidence at 25-30 months of age (Deerberg et… »
Human DAB2 wild-type allele is located within 5p13 and is approximately 52 kb in length. This allele, which encodes disabled homolog 2… »
This gene may play a role in tumor suppression. »
Human DAB2IP wild-type allele is located within 9q33.1-q33.3 and is approximately 218 kb in length. This allele, which encodes disabled homolog 2-interacting… »
A recombinant fusion protein composed of the diphtheria toxin with the receptor-binding domain replaced by human epidermal growth factor (EGF). When… »
A drug used alone or with trametinib to treat melanoma that cannot be removed by surgery or has spread to other… »
A rare, slow-growing tumor of blood vessels that forms in or under the skin anywhere on the body. Dabska tumors may appear… »
A substance being studied in the treatment of cancer. It is a type of topoisomerase inhibitor. Also called acridine carboxamide. »
A drug that is used to treat Hodgkin lymphoma and malignant melanoma and is being studied in the treatment of other types… »
A humanized monoclonal antibody directed against the CD40 receptor with potential antineoplastic activity. Dacetuzumab specifically binds to and inhibits the CD40 receptor,… »
A low molecular weight polymer-conjugated platinum complex with potential antineoplastic activity. This polymer drug delivery system consists of cytotoxic diaminocyclohexane (DACH)-platinum (Pt)… »
Polymeric micellar nanoparticles containing diaminocyclohexane platinum (DACH-platin or DACH-Pt) with potential antineoplastic activity. DACH-platin micelle NC-4016 is prepared through the formation of… »
The Dachshund is an elongated, vigorous, muscular dog with short legs. This breed has a long muzzle and robust jaws with extremely… »
A monoclonal antibody that is being studied in the treatment of adult T-cell leukemia and in the treatment of cytopenia (low blood… »
A monoclonal antibody that is being studied in the treatment of adult T-cell leukemia and in the treatment of cytopenia (low blood… »
A drug that is used to treat myelodysplastic syndromes and is being studied in the treatment of other types of cancer. It… »
A highly selective, orally bioavailable small-molecule inhibitor of the HER family of tyrosine kinases with potential antineoplastic activity. Dacomitinib specifically and irreversibly… »
A second-generation platinum analog with potential antineoplastic activity. Dacplatinum alkylates DNA at the N-7 position of guanine, thereby producing DNA interstrand… »
Inflammation of the lacrimal sac. (Dorland, 27th ed) »
The determination of the presence or absence of dacryocytes, abnormal erythrocytes shaped like a teardrop, seen in myelofibrosis and certain other myeloproliferative… »
This gene is involved in the regulation of signaling pathways. »
Human DACT2 wild-type allele is located in the vicinity of 6q27 and is approximately 27 kb in length. This allele, which encodes… »
A drug used to treat Ewing sarcoma, gestational trophoblastic tumor, Wilms tumor, and certain types of testicular cancer. It is also used… »
A genus of soil-dwelling fungi. »
Disability Assessment for Dementia (DAD) Adequately organize an outing with respect to transportation, keys, destination, weather, necessary money, shopping list? »
Disability Assessment for Dementia (DAD) Adequately organize his/her correspondence with respect to stationery, address, stamps? »
Disability Assessment for Dementia (DAD) Adequately plan a light meal or snack (ingredients, cookware)? »
Disability Assessment for Dementia (DAD) Attempt to telephone someone at a suitable time? »
Disability Assessment for Dementia (DAD) Brush his/her teeth or take care of his/her dentures appropriately? »
Disability Assessment for Dementia (DAD) Carry out an appropriate telephone conversation? »
Disability Assessment for Dementia (DAD) Choose appropriate clothing (with regard to the occasion, neatness, the weather and color combination)? »
Disability Assessment for Dementia (DAD) Choose appropriate utensils and seasonings when eating? »
Disability Assessment for Dementia (DAD) Complete household chores adequately as he/she used to perform in the past? »
Disability Assessment for Dementia (DAD) Decide that he/she needs to eat? »
Disability Assessment for Dementia (DAD) Decide to brush his/her teeth or care for his/her dentures? »
Disability Assessment for Dementia (DAD) Decide to care for his/her hair (wash and comb)? »
Disability Assessment for Dementia (DAD) Decide to dress himself/herself? »
Disability Assessment for Dementia (DAD) Decide to go out (walk, visit, shop) at an appropriate time? »
Disability Assessment for Dementia (DAD) Decide to prepare a light meal or snack for himself/herself? »
Disability Assessment for Dementia (DAD) Decide to take his/her medications at the correct time? »
Disability Assessment for Dementia (DAD) Decide to use the toilet at appropriate times? »
Disability Assessment for Dementia (DAD) Decide to wash himself/herself or to take a bath or shower? »
Disability Assessment for Dementia (DAD) Dress himself/herself completely? »
Disability Assessment for Dementia (DAD) Dress himself/herself in the appropriate order (undergarments, pant/dress, shoes)? »
Disability Assessment for Dementia (DAD) Eat his/her meals at a normal pace and with appropriate manners? »
Disability Assessment for Dementia (DAD) Find and dial a telephone number correctly? »
Disability Assessment for Dementia (DAD) Go out and reach a familiar destination without getting lost? »
Disability Assessment for Dementia (DAD) Handle his/her money adequately (deal with cash)? »
Disability Assessment for Dementia (DAD) Organize his/her finances to pay his/her bills (checks, bank statement, bills)? »
Disability Assessment for Dementia (DAD) Plan and organize adequately household chores that he/she used to perform in the past? »
Disability Assessment for Dementia (DAD) Sub-Total Planning and Organization Number of Applicable Items. »
Disability Assessment for Dementia (DAD) Prepare the water, towels, and soap for washing, taking a bath or a shower? »
Disability Assessment for Dementia (DAD) Return from the store with the appropriate items? »
Disability Assessment for Dementia (DAD) Prepare or cook a light meal or a snack safely? »
Disability Assessment for Dementia (DAD) Safely take the adequate mode of transportation (car, bus, taxi)? »
Disability Assessment for Dementia (DAD) Show an interest in leisure activity(ies)? »
Disability Assessment for Dementia (DAD) Show an interest in his/her personal affairs such as his/her finances and written correspondence? »
Disability Assessment for Dementia (DAD) Stay safely at home by himself/herself when needed? »
Disability Assessment for Dementia (DAD) Sub-total effective performance. »
Disability Assessment for Dementia (DAD) Sub-total effective performance number of applicable items. »
Disability Assessment for Dementia (DAD) Sub-total initiation. »
Disability Assessment for Dementia (DAD) Sub-total planning and organization. »
Disability Assessment for Dementia (DAD) Take an interest in household chores that he/she used to perform in the past? »
Disability Assessment for Dementia (DAD) Take care of his/her hair (wash and comb)? »
Disability Assessment for Dementia (DAD) Take his/her medications as prescribed (according to the right dosage)? »
Disability Assessment for Dementia (DAD) Total initiation number of applicable items. »
Disability Assessment for Dementia (DAD) Total number of applicable items. »
Disability Assessment for Dementia (DAD) DAD total in percent. »
Disability Assessment for Dementia (DAD) Total score. »
Disability Assessment for Dementia (DAD) Undress himself/herself completely? »
Disability Assessment for Dementia (DAD) Use the toilet without 'accidents'? »
Disability Assessment for Dementia (DAD) Wash and dry all parts of his/her body safely and completely? »
Disability Assessment for Dementia (DAD) Write and convey a telephone message adequately? »
A question associated with the DAD questionnaire. »
Human DAD1 wild-type allele is located 14q11.2 and is approximately 24 kb in length. This allele, which encodes dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1… »
Daflon 500 is a phlebotonic drug and a vascular protecting agent. It is reported to improve microcirculation in chronic venous insufficiency… »
The cysteine-rich N-terminal DAG/PE (Diacylglycerol/Phorbol Ester)-Binding (C1) Domain of PKC isoforms interacts with phorbol ester or with the phospholipid-derived second messenger… »
An isoflavone found in soy products. Soy isoflavones are being studied in the prevention of cancer. »
A specified quantity of a therapeutic agent to which an individual can be exposed to or was exposed to, during a one-day… »
Food made from the milk of some mammals, most commonly cows, goats and sheep. »
A highly diluted solution of sodium hypochlorite (0.5% w/v) with topical anti-infective activity. Dakin's solution is used as an antiseptic to clean… »
A soluble fusion protein containing the extracellular domain of activin receptor-like kinase-1 (ALK1) fused to a human Fc domain (ALK1-Fc fusion protein),… »
A cholesteryl ester transfer protein (CETP) inhibitor that can produce an increase in serum HDL-cholesterol levels and a decrease in serum LDL-cholesterol… »
A semi-synthetic derivative of streptogramin A produced by streptomycetes. Dalfopristin inhibits the early phase of protein synthesis in the bacterial ribosome by… »
The Dalmatian is a symmetrical, muscular medium-sized dog with superior endurance. It has a short, hard, dense coat of pure white… »
A recombinant humanized monoclonal antibody directed against the insulin-like growth factor 1 receptor (IGF1R) with potential antineoplastic activity. Dalotuzumab binds to membrane-bound… »
A drug used to prevent blood clots from forming or to treat blood clots that have formed in patients with cancer or… »
A drug used to prevent blood clots from forming or to treat blood clots that have formed in patients with cancer or… »
A prodrug inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase. In the body dalvastatin is hydrolyzed to its active beta-hydroxy acid… »
An alkaloid phytochemical found in the Morinda Citrifolia (Noni) that inhibits the growth of RAS cancer cells. The exact mechanism is unknown… »
The Damon Runyon Cancer Research Foundation is a non-profit organization dedicated to advancing cancer research. It encourages extraordinary young scientists to pursue… »
A device designed to reduce the flow of air through a duct or an electronic device designed to decrease the amplitude of… »
The Dan L Duncan Cancer Center focuses on cancer research, patient care, training, and education. It became an NCI-designated cancer center in… »
The Dana-Farber/Harvard Cancer Center is a cancer research consortium that integrates and builds on the collective talent and resources of seven Harvard-affiliated… »
The sodium salt form of danaparoid, a synthetic low molecular weight heparin (LMWH) derived from porcine gut mucosa with anticoagulant activity. Danaparoid… »
A synthetic hormone that is a type of androgen and is used to treat endometriosis. It is being evaluated in the treatment… »
The Dandie Dinmont Terrier is longer than he is tall with short and muscular legs. The solid head is covered with a… »
A rare congenital brain malformation disorder characterized by agenesis or hypoplasia of the cerebellar vermis, cystic dilatation of the fourth ventricle, and… »
A synthetic cytokine and interleukin-3 (IL-3) receptor agonist with enhanced hematopoietic potency. Daniplestim exhibits 10- to 20-fold greater biological activity than recombinant… »
A water-insoluble heterocyclic amide with potential antineoplastic activity. Daniquidone inhibits topoisomerases I and II, thereby inhibiting DNA replication and repair, and RNA… »
Climate oscillations averaging a few thousand years in duration that dominate Greenland ice-core records. »
A reddish, synthetic anthraquinone derivative. Danthron has been widely used as a laxative, but is no longer used to treat constipation and… »
A hydantoin derivative and direct-acting skeletal muscle relaxant. Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1,… »
The sodium salt form of dantrolene, a hydantoin derivative and direct-acting skeletal muscle relaxant. Dantrolene depresses excitation-contraction coupling in skeletal muscle by… »
A small-molecule 3-aminopyrazole derivative with potential antineoplastic activity. Danusertib binds to and inhibits the Aurora kinases, which may result in cell growth… »
A selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity. Dapagliflozin selectively and potently inhibits SGLT2 compared to SGLT1, which is… »
An alpha-1-adrenergic antagonist that acts by blocking alpha-adrenergic receptors in the smooth muscle of blood vessels (arteries, arterioles and veins), gastrointestinal tract,… »
A diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Dapivirine has activity against wild-type virus strains and strains harboring different NNRTI resistance-inducing mutations and may… »
This gene is involved in pro-apoptotic regulation. »
Human DAPK1 wild-type allele is located in the vicinity of 9q34.1 and is approximately 211 kb in length. This allele, which encodes… »
A small molecule with potential antineoplastic and antiangiogenic activities. Daporinad binds to and inhibits nicotinamide phosphoribosyltransferase (NMPRTase), inhibiting the biosynthesis of nicotinamide… »
Dapper homolog 2 (774 aa, ~83 kDa) is encoded by the human DACT2 gene. This protein is involved in the inhibition of… »
A drug used to treat acne. It is also used to treat other types of skin diseases and certain bacterial infections, such… »
The 5% gel preparation of dapsone, a synthetic derivative of diamino-sulfone with anti-inflammatory and anti-bacterial properties. As a structural analog of p-aminobenzoic… »
A drug used to treat certain bacterial skin and bloodstream infections in adults. Daptomycin is also being studied in the treatment of… »
A log of study drugs kept by an investigator running a clinical trial. It lists many things about each drug, including the… »
A substituted pyrimidone with inhibitory activity towards lipoprotein-associated phospholipase-A2 (Lp-PLA2), an important regulator of lipid metabolism and inflammation that circulates with lipoprotein… »
A fully human monoclonal antibody directed against the cell surface glycoprotein CD-38 with potential antineoplastic activity. The binding of anti-CD38 monoclonal antibody… »
A substance made in the laboratory that stimulates the bone marrow to produce red blood cells. It belongs to the family of… »
Human DARC wild-type allele is located within 1q21-q22 and is approximately 3 kb in length. This allele, which encodes Duffy antigen/chemokine receptor… »
An agent belonging to the glitazone class of antidiabetic agents with antihyperglycemic and anti-inflammatory activities. Darglitazone may be able to abrogate acute… »
The sodium salt form of darglitazone, an agent belonging to the glitazone class of antidiabetic agents with antihyperglycemic and anti-inflammatory activities. Darglitazone… »
An autosomal dominant inherited chronic skin disorder caused by mutations in the ATP2A2 gene. It is characterized by the development of yellow-brown… »
A small-molecule organic arsenical with potential antineoplastic activity. Although the exact mechanism of action is unclear, darinaparsin, a highly toxic metabolic intermediate… »
A wild-type zebrafish line, the stock of which was collected in Darjeeling, India in 1987. This line has been maintained through… »
A light microscopic technique in which the light that does not come into contact with the structures or details of interest is… »
A microscope (device used to magnify small objects) in which objects are lit at a very low angle from the side so… »
A morphologic finding indicating the presence of darkly stained macrophages that contain melanin. »
A regimen consisting of tamoxifen, cisplatin, dacarbazine and carmustine used for the treatment of advanced-stage or metastatic malignant melanoma. »
A cutaneous leiomyoma arising from the dartos muscle of the scrotum or labia majora. »
The thin layer of smooth muscle surrounding the scrotum which contracts or expands the scrotal skin to regulate testicular temperature. »
A drug used to treat multiple myeloma. It is used with dexamethasone and lenalidomide or bortezomib in patients whose cancer was treated… »
A drug used to treat certain types of chronic myeloid leukemia and acute lymphoblastic leukemia. Dasatinib is also being studied in the… »
An orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib binds to and inhibits the growth-promoting activities of these… »
A regimen consisting of daunorubicin, cytarabine (Ara-C) and thioguanine, used as an induction treatment for childhood acute myeloid leukemia (AML). »
A collection or single item of factual information, derived from measurement or research, from which conclusions may be drawn. »
A device designed to automatically receive and store data and format it for later use. »
An impartial group that oversees a clinical trial and reviews the results to see if they are acceptable. This group determines if… »
Issue associated with problems relating to a system, component, file, procedure, or person available to replace or help restore a primary item… »
Database management involves the design and maintenance of electronic data storage systems to facilitate and optimize the categorization, selection, and retrieval of… »
The act or process of gathering data for testing or research purposes. »
The Data Compilation and Analysis Shared Resource provides Cancer Center investigators with design and programming of relational databases for clinical, population and… »
The coding of data to save storage space or transmission time. »
Attributes from a data source that provide meaning that is relevant for annotation. »
The translation of computer data from one format to another. »
Event in which information is unintentionally permanently or temporarily lost, deleted, corrupted, or overwritten. »
A multidimensional representation of data which provides fast retrieval and drill down facilities. »
The date on which subsequently collected data will not be considered as part of the analysis. »
A textual description of the data cutoff date. »
A unit of data for which the definition, identification, representation and permissible values are specified by means of a set of… »
A concept that can be represented in the form of a data element, described independently of any particular representation. »
A description of the affiliation between two occurrences of Data Element Concepts. »
The data element component(s) used for a derived data element. »
A collection of data elements, or Common Data Elements, logically grouped on a case report form. »
The affiliation between two occurrences of Data Elements. »
An artifact resulting from an error in data collection. »
A process whereby specific data is taken out of a larger set of data and presented in a usable format. »
An area of database record, or graphical user interface form, into which a particular item of data is entered. »
A grid service that provides an API with a query method, which allows the querying of any class or attribute in the… »
Processes for data acquisition, validation, storage, protection, and processing. »
A person primarily responsible for database creation, data collection, validation, integration, coding, review, quality evaluation, and archiving, as well as for preparation… »
Data that can not be released due to confidentiality issues or for other reasons. »
The primary point where the data was generated or collected. »
An connective access point for telecommunication devices, such as modems or fax machines, for the transmission of data. »
A series of operations on data by a computer in order to retrieve or transform or classify information. »
The person or authoritative body who provided the information. »
A statement that defines conventions, guidelines, characteristics or methods for consistent data handling to facilitate exchange or processing of the data. This… »
A set of data arranged in rows and columns. »
A process whereby data is changed from one format to another. »
An indication of the form that a value will have. Examples include string, integer, and character. »
The information contained in a data field. It may represent a numeric quantity, a textual characterization, a date or time measurement, or… »
An information set with a regular structure. Although it can be applied to any set of information the term was invented… »
An expression of both date and time that an event has happened or will happen. »
Dates on which an animal model record was entered, modified or release to the intended viewing audience. »
A string unique to a time duration of 24 hours between 2 successive midnights defined by the local time zone. The specific… »
The sweet edible fruit of the date palm with a single long woody seed. »
The date that a documented cardiac arrest occurred. »
The date that a specific cardiac diagnostic procedure was performed. »
The date that a specific cardiac therapeutic procedure was performed. »
The calendar date of subject's death. »
The date of the beginning of the first ever occurrence of the symptom complex of angina pectoris. »
The date of the beginning of the first ever occurrence of heart failure. »
The date of the heart failure event requiring an individual to seek medical attention. »
The date of the most recent occurrence of heart failure. »
The date that a documented myocardial infarction occurred. »
A date on which an event or observation was reported. »
The date of a cardiac arrest event that was reversed, usually by cardio-pulmonary resuscitation and/or defibrillation or cardioversion, or cardiac pacing. … »
The date that a specific therapeutic procedure was performed. »
The date and time span specifying when an activity or event began and ended. »
The date and time of the angina pectoris event requiring an individual to seek medical attention. »
The date and time of the most recent occurrence of angina pectoris. »
The date and time of the beginning of the symptom complex of angina pectoris. »
Issue associated with programming of calendar dates and/or time as a factor in the operation of a medical device. »
The wife of your son. »
The active ingredient in a drug used to treat acute leukemias and some other types of cancer. It blocks a certain enzyme… »
A drug used to treat acute leukemias and some other types of cancer. It blocks a certain enzyme needed for cell division… »
The active ingredient in a drug used to treat acute leukemias and some other types of cancer. It blocks a certain enzyme… »
