Medicine
The hydrochloride salt form of dopamine, a monoamine compound with positive inotropic activity. Dopamine is a naturally occurring catecholamine formed by decarboxylation… »
The determination of the amount of dopamine hormone present in a sample. »
Cell-surface proteins that bind dopamine with high affinity and trigger intracellular changes influencing the behavior of cells. »
Dopamine receptor D1 protein (446 aa, 49 kD) is a cell communication process protein that is encoded by the human DRD1 gene… »
Neurotransmission mediated by the Dopamine D2 Receptor (DRD2) plays a key role in the control of movement, in reward and reinforcement mechanisms… »
Dopamine receptor D4 protein (467 aa, 48 kD) is a cell communication proccess protein that is encoded by the human DRD4 gene… »
Dopamine receptor D5 protein (477 aa, 53 kD) is a cell communication proccess protein that is encoded by the human DRD5 gene… »
A finding indicating that an excess amount of dopamine is secreted by a tumor. »
A chimeric molecule directed against dopamine and somatostatin receptors with potential antineoplastic activity. Combining two pharmacological moieties, a somatostatin analogue and a… »
A nerve cell that employs dopamine as its neurotransmitter. »
A procedure that uses sound waves to measure characteristics of disturbed bood flow, such as direction, velocity and turbulence. This enables the… »
Diagnostic imaging that uses sound waves (ultrasound) applying the Doppler effect, with frequency-shifted ultrasound reflections produced by moving targets (usually red blood… »
A broad-spectrum, carbapenem antibiotic with bactericidal and beta-lactamase resistant activities. Doripenem binds to penicillin binding proteins (PBPs) located on the bacterial cell… »
A drug given in an aerosol mist to decrease the thickness of mucus in the lungs of patients with cystic fibrosis. It… »
A locus on the floor of the lateral surface of the fourth ventricle where auditory nerves form the cochlea synapse in the… »
A spinal curve that originates at the middle of the second thoracic vertebra and terminates at the middle of the last thoracic… »
Four muscles in the foot between the metatarsal bones extending down the medial and lateral sides of the proximal phalanx of the… »
Four muscles in the hand between the metacarpal bones originating on the radial side of the metacarpal as well as the ulnar… »
The posterior column of gray matter extending the length of the spinal cord. »
Site of initiation of gastrulation in the amphibian embryo. The dorsal lip, which forms at the site of the gray crescent, forms… »
One of the four blood vessels arising from the dorsal carpal arch that runs down the posterior side of the second, third,… »
The vessels carrying deoxygenated blood on the upper side of the foot that originate from the dorsal digital vein creating the dorsal… »
A brain nucleus located in the medulla oblongata. »
A muscle located on the posterior aspect of the trunk. »
A vessel arising from the ophthalmic artery that supplies the skin of the root of the nose with oxygenated blood. »
The area pertaining to the top of the foot. »
Ganglion with sensory function within the vertebral column. »
Observation chambers, implanted in various animal species and in man, used for intravital microscopy of the microcirculation in granulation tissue, preformed tissue,… »
A developmental morphogenetic process that establishes the basic configuration of cellular organization necessary for further and accurate development of the spatial arrangement… »
An artery of the dorsal surface of the foot, originating from the anterior tibial artery of the lower leg. The following… »
Any artery arising from the dorsalis pedis artery. »
Of or involving the back and side of a main body. »
The dorsolateral lobe of the prostate gland in animals. »
Of or involving the back and belly of the main body. »
An inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid conversion of carbon dioxide and water into carbonic acid, protons… »
The hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid conversion of carbon dioxide… »
The sodium salt of Dorzolamide. An inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid conversion of carbon dioxide… »
A classification scheme to categorize dosage forms. »
A substance intended for administration as a solution. »
A substance intended for administration as a suspension. »
An indication that the dosage form is not relevant or appropriate. »
The unit of measure for the dosage form. »
An indication or description of a change in dosage. »
The explanation given as to why a dosage was adjusted. »
Device which quantifies an amount of radioactive substance. It would give the number of Becquerels or Curies present at a particular noted… »
Terminology used in Individual Case Safety Reports for description of the recipient of a dose. »
A textual description of the agent dose level(s) or range(s) assigned to a subject according to the study protocol. »
A stepwise increase in the amount of a therapeutic or investigational agent given to an individual. »
An artifact resulting from the leakage of an imaging agent from its location of administration. »
The number of times a substance is administered within a specific time period. »
A coded value specifying how often a dose is administered. »
An indication that a medication schedule was modified by addition; either by changing the frequency, strength or amount. »
The product of the number of computed tomography (CT) scans multiplied by the scan width (i.e., total scan length). This value is… »
Change, alteration, or adjustment of a dose specified in a treatment plan or/and administered to a patient. »
An indication that a medication schedule was continued without modification. »
A dosing unit equal to the amount of active ingredient(s) contained in a dosepack. »
A coded value specifying the period during which the dose is administered. »
An indication that a medication schedule was modified by subtraction, either by changing the frequency, strength or amount. »
A treatment plan that specifies the amount, schedule, and the duration of intervention(s). »
A plot of a cumulative dose-volume frequency distribution that graphically summarizes the simulated radiation distribution within a volume of interest of a… »
A chemotherapy treatment plan in which drugs are given with less time between treatments than in a standard chemotherapy treatment plan. … »
Refers to the effects of treatment with a drug. If the effects change when the dose of the drug is changed, the… »
Describes side effects of a drug or other treatment that are serious enough to prevent an increase in dose or level of… »
Medición de la exposición a la radiación de los rayos X, los rayos gamma u otros tipos de radiación que se usan… »
A person who determines the proper radiation dose for treatment. »
Persona que determina la dosis correcta de radiación para un tratamiento. »
Measurement of radiation exposure from x-rays, gamma rays, or other types of radiation used in the treatment or detection of diseases, including… »
Cantidad que se toma de medicina o cantidad que se administra de radioterapia en un momento dado. »
En el campo de la medicina, la cantidad total de un medicamento o radiación que se administra a un paciente en un… »
Dosis única de un medicamento u otra sustancia administrada durante un período de tiempo corto. Habitualmente se administra por inyección… »
Dosis más alta de un medicamento o tratamiento que no causa efectos secundarios inaceptables. La dosis máxima tolerada se determina en ensayos… »
A procedure that uses light waves to create 3-dimensional (3-D) pictures of tissues inside the body. The pictures are created by a… »
This gene is involved in epigenetic control of gene expression. »
A small molecule inhibitor of histone methyltransferase with potential antineoplastic activity. Upon intravenous administration, EPZ-5676 specifically blocks the activity of the histone… »
Human DOT1L is located in the vicinity of 19p13.3 and is approximately 66 kb in length. This allele, which encodes histone lysine… »
A formulation composed of DOTAP:cholesterol liposomal nanoparticles complexed with a plasmid expression cassette encoding human FUS1 protein, with potential antineoplastic activity. Upon… »
A bone-seeking chelating agent. Has been used as a radiopharmaceutical in complexes with radioactive metals for bone marrow ablation. »
A procedure used to look at the inside of the small intestine. A special instrument made up of two tubes (one inside… »
A procedure used to look at the inside of the small intestine. A special instrument made up of two tubes (one inside… »
A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually… »
The shape of two circles joined together, and usually overlapping. »
Double coded data and samples are initially labelled with a single code and do not carry any personal identifiers. The data and… »
A locality or minor thoroughfare the address for which must be specified in relationship to a more major one. »
Double homeobox protein 4 (424 aa, ~45 kDa) is encoded by the human DUX4 gene. This protein plays a role in the… »
A rare congenital cardiovascular abnormality in which both the aorta and the pulmonary artery arise from the right ventricle. »
An internal radiation treatment technique in which radioactive seeds are embedded in suture material and directly affixed to target cancerous tissue. … »
Mechanisms of DNA repair associated with radiation damage. »
A virus that has double stranded DNA as its genetic material. »
A virus that has double stranded RNA as its genetic material. »
A clinical trial in which the medical staff, the patient, and the people who analyze the results do not know the specific… »
A procedure in which x-rays of the colon and rectum are taken after a liquid containing barium is put into the… »
A rare, aggressive (fast-growing) type of B-cell non-Hodgkin lymphoma caused by changes in the DNA that affect a gene called the MYC… »
Double-strand break repair protein MRE11A (708 aa, ~81 kDa) is encoded by the human MRE11A gene. This protein plays a role in… »
Double-strand-break repair protein rad21 homolog (631 aa, ~72 kDa) is encoded by the human RAD21 gene. This protein is involved in DNA… »
An RNA complex consisting of two complementary base-paired strands of RNA. »
The Double-Stranded RNA Binding Domain is found in a variety of RNA-binding proteins with different structures and exhibiting a diversity of… »
A carbon nanotube comprised of two layers of graphitic carbon. »
An amplifier that doubles the voltage or frequency of an input signal. »
Doublesex- and mab-3-related transcription factor 1 (373 aa, ~39 kDa) is encoded by the human DMRT1 gene. This protein plays a role… »
In biology, the amount of time it takes for one cell to divide or for a group of cells (such as a… »
A procedure in which the vagina is washed with water or a cleansing solution. Most cleansing solutions contain water mixed with vinegar,… »
A substance intended for use as a vaginal irrigant. »
A powder which may be mixed with a liquid, intended for administration as a vaginal irrigant. »
A solution intended for use as a vaginal irrigant. »
A benzimidazole-quinolinone compound and receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Dovitinib binds to and inhibits the phosphorylation of type… »
The orally bioavailable lactate salt of a benzimidazole-quinolinone compound with potential antineoplastic activity. Dovitinib strongly binds to fibroblast growth factor receptor 3… »
A disorder caused by the presence of an extra chromosome 21 and characterized by mental retardation and distinguishing physical features. »
An enhancer which is located 3' of the gene it regulates. »
Vertical strabismus in which there is permanent downward deviation of the visual axis of one eye. »
A form of the anticancer drug doxorubicin that is contained in very tiny, fat-like particles. It may have fewer side effects and… »
Forma de doxorrubicina, un medicamento contra el cáncer, que está contenida en partículas diminutas semejantes a la grasa. Puede tener menos efectos… »
A synthetic partial beta-adrenergic agonist with sympathomimetic activity. Doxaminol may bind to and stimulate beta-1-adrenergic receptors located in the myocardium. As a… »
A respiratory stimulant with analeptic activity. Doxapram, independent of oxygen levels, directly stimulates the peripheral carotid chemoreceptors, possibly by inhibiting the potassium… »
A peripheral and central respiratory stimulant with a brief duration of action. Doxapram hydrochloride stimulates respiration by an action on chemoreceptors in… »
A drug used to treat high blood pressure and urinary problems caused by an enlarged prostate. It relaxes muscle tissue in blood… »
A drug used to treat high blood pressure and urinary problems caused by an enlarged prostate. It relaxes muscle tissue in blood… »
Medicamento que se usa para tratar la presión arterial alta y los problemas urinarios causados por una próstata agrandada. Relaja el tejido… »
A dibenzoxepin derivative and tricyclic antidepressant with antipruritic and sedative activities. Doxepin blocks the reuptake of norepinephrine and serotonin into presynaptic terminals… »
A substance being studied in the prevention of recurrent prostate cancer. It is a type of vitamin D analog. »
Sustancia en estudio para la prevención del cáncer de próstata recurrente. Es un tipo de análogo de la vitamina D. »
Medicamento que se usa para tratar muchos tipos de infecciones bacterianas. Impide el crecimiento de las bacterias porque les impide elaborar… »
A fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity. Doxifluridine, designed to circumvent the rapid degradation… »
A form of the anticancer drug doxorubicin that is contained in very tiny, fat-like particles. It may have fewer side effects and… »
Forma de doxorrubicina, un medicamento contra el cáncer, que está contenida en partículas diminutas semejantes a la grasa. Puede tener menos efectos… »
Medicamento que se usa para tratar muchos tipos de cáncer y que está en estudio para el tratamiento de otros tipos de… »
A drug that is used to treat many types of cancer and is being studied in the treatment of other types of… »
A drug that is used to treat many types of cancer and is being studied in the treatment of other types of… »
A form of the anticancer drug doxorubicin that is contained in very tiny, fat-like particles. It may have fewer side effects and… »
A compound drug containing doxorubicin as an active ingredient. »
A regimen consisting of doxorubicin and cisplatin used for the treatment of malignant mesothelioma; also used with or without surgical resection for… »
A complex comprised of Doxorubicin linked to DNA to enhance the topoisomerase II-mediated interaction with the DNA base pairs and reduce cardiotoxicity… »
A regimen consisting of doxorubicin and docetaxel used for the treatment of metastatic breast cancer. »
A drug-device combination product consisting of small polymeric beads impregnated with the anthracycline antibiotic doxorubicin with potential antineoplastic activity. The beads consist… »
A copolymer conjugate of the antineoplastic anthracycline doxorubicin and the water-soluble polymer N-(2-hydroxypropyl) methacrylamide (HPMA). Doxorubicin, an intercalator and a topoisomerase II… »
A formulation of the anthracycline antibiotic doxorubicin in which doxorubicin is bound to microscopic beads of activated carbon and iron as a… »
A drug used to treat many types of bacterial infections. It stops the growth of bacteria by keeping them from making… »
The calcium salt form of doxycycline exhibiting antimicrobial activity. Doxycycline blocks binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein… »
A drug used to treat many types of bacterial infections. It stops the growth of bacteria by keeping them from making… »
The hydrochloride salt form of doxycycline exhibiting antimicrobial activity. Doxycycline blocks binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein… »
The monohydrate form of doxycycline exhibiting antimicrobial activity. Doxycycline blocks binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein… »
A first generation ethanolamine with antiinflammatory, sedative and antihistamine properties. Doxylamine competitively inhibits the histamine 1 (H1) receptor, thereby preventing the action… »
A pyridine derivate histamine H1 antagonist with pronounced sedative properties. Doxylamine succinate competitively blocks the histamine H1 receptor and limits the typical… »
A question about an individuals likelihood to doze or fall asleep. »
A type of power of attorney. A power of attorney is a legal document that gives one person (such as a relative,… »
Human DPP4 wild-type allele is located in the vicinity of 2q24.3 and is approximately 82 kb in length. This allele, which encodes… »
This gene plays a role in stem cell biology. »
Human DPPA3 wild-type allele is located in the vicinity of 12p13.31 and is approximately 6 kb in length. This allele, which encodes… »
Human DPYD wild-type allele is located within 1p22 and is approximately 843 kb in length. This allele, which encodes dihydropyrimidine dehydrogenase [NADP+]… »
Human DR1 wild-type allele is located in the vicinity of 1p22.1 and is approximately 17 kb in length. This allele, which encodes… »
Dr1-associated corepressor (205 aa, ~22 kDa) is encoded by the human DRAP1 gene. This protein is involved in the repression of gene… »
Apoptosis is specifically induced via signaling through a family of receptors known collectively as 'death receptors' including Fas, TNFR, DR3, -4 and… »
A protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer cells. An increase… »
Proteína en la superficie de ciertas células que se une a otra proteína que se llama TRAIL, que puede destruir algunas células… »
A protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer cells. An increase… »
Proteína de la superficie de ciertas células que se une a otra proteína que se llama TRAIL, que puede destruir células… »
A parasitic infection caused by Dracunculus medinensis. It is caused by drinking water contaminated with water fleas. The larvae enter the body… »
In medicine, to remove fluid as it collects; or, a tube or wick-like device used to remove fluid from a body cavity,… »
The non-SI unit of mass equal to 1/16 Avoirdupois ounce or 1/256 Avoirdupois pound. One dram equals approximately 1.7718451953125 grams. »
This gene plays a role in repression of transcription. »
Human DRAP1 wild-type allele is located in the vicinity of 11q13.3 and is approximately 2kb in length. This allele, which encodes Dr1-associated… »
Represent by making a drawing of, as with pencil, chalk, etc. on a surface; make a mark or lines on a… »
This gene is involved in the regulation of dopamine receptor transport and neuronal signal transduction pertaining to neuronal growth and development. … »
Human DRD1 wild-type allele is located in the vicinity of 5q35.1 and is approximately 3 kb in length. This allele, which encodes… »
Human DRD2 Gene at 11q23 encodes Dopamine Receptor D2, a G-protein coupled receptor that inhibits adenylyl cyclase activity. Missense mutation in DRD2… »
Human DRD2 Gene at 11q23 encodes Dopamine Receptor D2, a G-protein coupled receptor that inhibits adenylyl cyclase activity. Missense mutation in DRD2… »
Human DRD2 wild-type allele is located within 11q23 and is approximately 66 kb in length. This allele, which encodes D(2) dopamine receptor… »
This gene plays a role in G protein-coupled receptor signal transduction and inhibits adenylyl cyclase activity. »
Human DRD4 wild-type allele is located in the vicinity of 11p15.5 and is approximately 3 kb in length. This allele, which encodes… »
This gene plays a regulatory role in adenylate cyclase activity and intracellular cAMP store accumulation. The gene is thought to act as… »
Human DRD5 wild-type allele is located in the vicinity of 4p16.1 and is approximately 2 kb in length. This allele, which encodes… »
An examination in which a doctor inserts a lubricated, gloved finger into the rectum to feel for abnormalities. Also called digital rectal… »
A mental phenomenon occurring during sleep in which images, emotions, and thoughts are experienced with a sense of reality; occurs during REM… »
A chain of extinct underwater volcanoes rising 1000m or higher above the sea floor, either flat-topped or peaked and located in the… »
Procedimiento que se usa para drenar la bilis y aliviar la presión que causa una obstrucción en los conductos biliares. Una radiografía… »
Flujo de linfa de un área de tejido a un ganglio linfático determinado. »
En medicina, extraer un líquido a medida que se acumula. Un drenaje es un tubo o un dispositivo que se utiliza para… »
Dresden prostate carcinoma protein 2 (172 aa, ~20 kDa) is encoded by the human HMGN2P46 gene. This protein may be involved in… »
A substance intended for administration in or on a wound. »
A set of guidelines developed by U.S. and Canadian scientists to give information about the role of nutrients in human health. These… »
Ingestas Alimentarias de Referencia (Dietary Reference Intakes). Serie de pautas establecidas por científicos de los Estados Unidos y Canadá para brindar información… »
Tissue which has been kept dry. »
Potable water for consumption. »
A question about whether an individual drinks alcohol, such as beer or wine. »
A computer interface designed to control the interaction between a CPU and a peripheral device. »
El término drogas de club se refiere a una amplia variedad de drogas peligrosas. Estas drogas suelen ser consumidas por adultos jóvenes… »
El abuso de drogas es un problema serio de salud pública que afecta a casi todas las comunidades y familias de algún… »
A phenolic analogue of tamoxifen, a nonsteroidal selective estrogen receptor modulator (SERM). Droloxifene competitively inhibits the binding of estradiol to estrogen… »
A synthetic anabolic steroid related to dihydrotestosterone that has antiestrogenic effects. Dromostanolone inhibits the growth of estrogen receptor-presenting breast cancers; its virilizing… »
The propionate salt form of dromostanolone, a synthetic anabolic steroid related to dihydrotestosterone that has antiestrogenic effects. Dromostanolone inhibits the growth… »
A synthetic pill form of delta-9-tetrahydrocannabinol (THC), an active ingredient in marijuana that is used to treat nausea and vomiting associated with… »
Forma sintética en pastilla del delta-9-tetrahidrocannabinol (THC), un ingrediente activo de la marihuana que se usa para tratar las náuseas y los… »
The determination of the amount of dronabinol present in a sample. »
A unit of volume in British Imperial system equal to 1/36 fluid dram or approximately 99 microliters. »
A substance intended for administration in a drop-wise fashion. »
An intradural extramedullary spinal metastasis from an intracranial tumor through the cerebrospinal fluid. »
A measure of intravenous fluid flow rate equal to the volume of intravenous fluid to be administered in milliliters multiplied by the… »
A solution intended for administration in a drop-wise fashion. »
A suspension intended for administration in a drop-wise fashion. »
A suspension prepared immediately prior to dispensing or administration in a drop-wise fashion. »
A drug used to prevent nausea and vomiting in patients who receive anesthesia before surgery. It is also used to treat… »
Medicamento que se usa para prevenir las náuseas y los vómitos en pacientes que reciben anestesia antes de la cirugía. También se… »
A pipet consisting of a small tube with a vacuum bulb at one end for drawing liquid in and releasing it a… »
A bottle that has a device specifically intended for the application of a liquid in a drop by drop manner, or a… »
A genus of small, American flies, Diptera. The best known species is D. Melanogaster, often called the fruit fly, but more correctly… »
Drosophila Patched Gene (Patched Family) encodes Patched protein, an integral membrane protein containing an SSD domain that acts as a segmentation polarity… »
Proteins found in Drosophila. »
Endogenous protein complexes found in Drosophila. »
An ATP-dependent chromatin-remodeling complex implicated in the regulation of gene expression, cell cycle control, and oncogenesis that is found in Drosophila. This… »
A synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity. Drospirenone binds to the progesterone receptor, the resulting complex becomes activated… »
A combination of two steroid sex hormones, the estrogen ethinyl estradiol and a progestin drospirenone, used for contraceptive purposes. The combination… »
People drown when they get too much water in their lungs. You can drown in as little as an inch or two… »
A drug used to treat certain patients with sickle cell anemia. It is also being studied in the treatment of other conditions… »
Any substance, other than food, that is used to prevent, diagnose, treat or relieve symptoms of a disease or abnormal condition. Also… »
The use of illegal drugs or the use of prescription or over-the-counter drugs for purposes other than those for which they are… »
The outcome of the drug accountability examination. »
The explanation given as to why drug accountability was not assessed. »
The unit of measure for the original drug accountability result. »
A character or string that represents the drug accountability assessment. »
A character or string that represents a drug accountability assessment. »
The standard character or string for representation and reporting of drug accountability data. »
A term used to describe the state or condition of the completeness of the drug accountability data. »
The date that the drug accountability assessments occurred on. »
The date and time of the drug accountability data. »
The day that a drug accountability assessment is performed. »
A character or string used to name or characterize the reference identifier for a dispensed treatment label with regards to a drug… »
A subject domain utilized for the submission of information encompassing and representing data, vocabulary or records related to drug accountability. »
A character or string that represents a drug accountability group. »
The numerical identifier of a drug accountability assessment result in standard units. »
An indication or description that a drug accountability test has occurred. »
A log of study drugs kept by an investigator running a clinical trial. It lists many things about each drug, including the… »
A classification of the drug accountability. »
A sub-division of the drug accountability classification. »
A character or string used to name, or characterize a drug accountability reference. »
The standard unit of measure for drug accountability results. »
A character or string used to name or characterize the reference identifier for a returned treatment label with regards to a drug… »
A number that identifies the ordering relations (in time, space, etc.) in a set of drug accountability data. »
One or more sponsor defined characters used to identify, name, or characterize the drug accountability assessment. »
The drug accountability information that indicates the date that the study treatment was dispensed. »
The The drug accountability information that indicates the date that the study treatment was returned. »
An identifier for a drug that was administered. »
The reactive parts of a macromolecule that directly participate in its specific combination with a drug. »
The determination of the levels of all members of a specific drug class present in a sample. »
A company licensed to discover, develop, market and distribute drugs. »
A person who acts as a channel for communication with a commercial enterprise which produces substances intended for use in the diagnosis,… »
Modern technology, distributed with or as a part of a drug product that allows for the uniform release or targeting of drugs… »
Drug dependence - replaced the term "drug addiction" and is defined as a state, psychic and sometimes also physical, resulting from the… »
Design, identification, synthesis, extraction, purification, modification, or characterization of potential anticancer agents; studies of their metabolism, distribution, excretion, physiological effects, molecular interactions,… »
Drug development activites focused on clinical trials and testing. »
Drug development activites focused on the phases preceding preclinical trials and testing. »
Drug development activites focused on preclinical trials and testing. »
A reference source that provides meanings of words related to drugs. »
Self-identified projects in the Biochemistry and Pharmacology Cancer Activity. »
Transport of drugs out of a cell. A mechanism of drug resistance. »
A vascular metal mesh tube coated with medication. The drug coating is intended to lessen the likelihood of restenosis. »
The term describes the situation in which a constant drug dose elicits increasing effects.The condition is opposite to drug tolerance since less… »
Leakage of drug from a vein into the surrounding tissue. »
An identifier for a drug for which administration has ended. »
A drug (other than the bulk ingredient API) that is in an interim stage of manufacture, processing, preparation, or packaging, and not… »
The act or process of developing or preparing a mixture of ingredients to create a desired end drug product, such as a… »
A process that forms a dosage that is not otherwise specified. »
A coded value specifying special handling requirements for the drug. EXAMPLE(S): keep at room temperature, store upright. »
A potentially life-threatening hypersensitivity reaction to a pharmacologic substance that is characterized by rash, lymphadenopathy, fever, hematologic abnormalities and involvement of one… »
Small containers or pellets of a solid drug implanted in the body to achieve sustained release of the drug. »
A reaction to a drug characterized by skin findings common to lupus including photosensitivity and butterfly rash; typically it resolves after drug… »
A skin hypersensitivity reaction characterized by raised purpuric lesions, red macules, hemorrhagic blisters and ulcerations. »
Overgrowth of the gingival tissue caused by phenytoin, cyclosporine A, and calcium channel blockers. »
Using pharmaceutical agents to influence uterine contractions and start labor during the childbirth process. »
Damage to the liver tissue due to drug overdose. »
Methemoglobinemia that is caused by exposure to certain drugs (xylocaine and benzene). »
Thrombocytopenia caused by ingested or injected drugs. It may be the result of decreased platelet production due to bone marrow suppression or… »
A change in the way a drug acts in the body when taken with certain other drugs, herbals, or foods, or when… »
An indication that a medication schedule was modified by temporarily terminating a prescribed regimen of medication. »
A packaged set of related pharmaceutical or and/or drug delivery devices used for a particular medical activity or procedure including required documentation… »
A Drug Master File (DMF) is a submission to the Food and Drug Administration (FDA) that may be used to provide confidential… »
A series of chemical modifications of a drug compound by enzymatic activity that make the substrate (drug) more water soluble to allow… »
A finding indicating a deficiency or excess in metabolism of one or more drugs. »
Drug Metabolism Induction involves the initiation of enzymatic biotransforming chemical modifications exerted on a naturally occurring or synthetically produced organic or inorganic… »
Drug Metabolism Inhibition involves interference with, or restraint of, enzymatic biotransforming chemical modifications exerted on a naturally occurring or synthetically produced organic… »
Substances that are grouped or classified by chemical composition. »
The drug product container with any accompanying materials or components. This may include the protective packaging, labeling, administration devices, etc. »
An elaboration of a sequence of physiological events that are elicited by the administration of a drug. »
Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high… »
A category based upon the characteristics of release of active and/or inert ingredient(s). »
The failure of cancer cells, viruses, or bacteria to respond to a drug used to kill or weaken them. The cells, viruses,… »
Treatment used to make cancer cells less resistant to anticancer drugs. »
Mechanisms, functions, activities, or processes exhibited by tumors or pathogens to withstand previously toxic drugs. »
The determination of whether the microbe or lesion is resistant to drugs normally used in treatment. »
A coded value specifying the type of hazard or threat associated with the drug. »
In the U.S., the government's Food and Drug Administration (FDA) must approve any drug before it can be sold. This is true… »
Drug Sample (PDS) »
The term describes the situation in which a constant drug dose elicits increasing effects.The condition is opposite to drug tolerance since less… »
The period of time during which the drug is considered usable after it is activated (opened). »
An identifier for a drug for which administration has started. »
A branch of the Developmental Therapeutics Program of the National Cancer Institute. It is responsible for activities that support the discovery and… »
A laboratory test of biological material such as blood, urine, hair, saliva or sweat, used to detect the presence of a drug… »
Treatment with any substance, other than food, that is used to prevent, diagnose, treat, or relieve symptoms of a disease or abnormal… »
A condition that occurs when the body gets used to a medicine so that either more medicine is needed or different medicine… »
An adverse effect of a drug used therapeutically or diagnostically. »
Any subcellular or molecular event, process, or condition involved in translocation of a drug from one site or compartment to another. … »
A description of an individual's current and past use and/or abuse of drugs and chemicals. This includes prescription medication, illicit drugs and… »
A carrier or inert medium used as a solvent (or diluent) in which a medicinally active agent is formulated and or… »
A unit used to express a volume of a carrier or inert medium in which a medicinally active agent is formulated and/or… »
A volume of a carrier or inert medium used as a solvent in which a medicinally active agent is formulated and/or administered… »
An indication that a medication schedule was modified through termination of a prescribed regimen of medication. »
An embolic bead that, in addition to blocking blood flow, also releases a chemotherapeutic drug. »
A state of bone marrow suppression and failure that is caused by a cytotoxic or adverse immunologic response to a drug treatment,… »
An organic or inorganic substance, element, isotope, food or other materials derived from microorganism, plant, or animal sources. They can be used… »
Any drug derived from microorganisms, plants, or animals; also, synthesized versions of these substances or their derivatives. »
Bone marrow failure defined as pancytopenia, due to exposure to a known toxin or drug. »
Substances that are grouped and described by their effects on biological functions rather than by their chemical structures. »
Drug abuse is a serious public health problem.It affects almost every community and family in some way. Drug abuse in children… »
A dosing unit equal to the amount of active ingredient(s) contained in a drum. »
A syndrome characterized by dryness of the cornea and conjunctiva. It is usually caused by a deficiency in tear production. Symptoms include… »
A sterilization process that uses high temperature and dry air to kill microorganisms on the surface of objects. This process is restricted… »
A solid form of carbon dioxide used as a refrigerant. At temperatures above -78.5 degrees C and ambient pressure, it changes directly… »
Dry mouth is the feeling that there is not enough saliva in your mouth. Everyone has a dry mouth once in a… »
A question about an individual's dry mouth at its worst. »
Sexual climax without the release of semen from the penis. »
A traditional (non-SI) unit of volume equal to two British gallons, or approximately 9.09218 liters. »
A traditional (non-SI) unit of volume equal to 1/8 dry US gallon, or approximately 0.550611 liter. »
Mixing of dry ingredients with the addition of a small amount of liquid, done to increase binding capability. »
Mixing of dry ingredients by mechanical agitation within a containment zone. »
Mixing of dry ingredients by repetitive tumbling. »
Mixing of dry ingredients by dispersion and turbulence within a flowing stream of gas. »
The act of forming granules by mechanically applying pressure by rollers to form a compact that is subsequently milled and screened resulting… »
A container used to ship products frozen in liquid nitrogen. It is designed so that the liquid nitrogen is absorbed into retention… »
The pores are generally fine with a papery thin texture that feels dry to the touch. Usually flaky and dull looking. … »
The act of forming granules by mechanically applying pressure by punch and die to form a compact that is subsequently milled and… »
A process that removes water or volatile solvents from a bed of solids. »
A process that is not otherwise specified, which removes water or a volatile solvent by evaporation. »
Disease Steps (DS) Methods: For Disease Steps, classification of a patient is determined by history and neurologic examination as well as course… »
A question associated with the DS questionnaire. »
Plasma cell myeloma with all of the following: 1. Hemoglobin greater than 10 g/Dl, 2. Normal serum calcium, 3. Normal bone structure,… »
Plasma cell myeloma that fits in neither stage I nor stage III. Estimated myeloma cell mass: 0.6 to 1.2 trillion (1012)/m2… »
Plasma cell myeloma with one or more of the following: 1. Hemoglobin less than 8.5 g/dL. 2. Serum calcium greater than 12.0… »
Human DSG3 wild-type allele is located in the vicinity of 18q12.1 and is approximately 31 kb in length. This allele, which encodes… »
Data and Safety Monitoring Board. An impartial group that oversees a clinical trial and reviews the results to see if they are… »
Este es un grupo imparcial que supervisa un estudio clínico y examina los resultados para ver si son aceptables. Este grupo determina… »
Human DSP wild-type allele is located in the vicinity of 6p24 and is approximately 45 kb in length. This allele, which encodes… »
One defense against viral infection is provided by PKR, double-stranded RNA activated protein kinase. When PKR interacts with dsRNA found in cells… »
Human DST wild-type allele is located in the vicinity of 6p12.1 and is approximately 497 kb in length. This allele, which encodes… »
A regimen consisting of dexamethasone, thalidomide (DT) and cisplatin, doxorubicin, cyclophosphamide and etoposide (PACE) used for the treatment of relapsed and refractory… »
A recombinant protein consisting of human interleukin 3 (IL3) fused to the first 388 amino acids of diphtheria toxin [DT(388)] with potential… »
A substance being studied in the treatment of some types of B-cell cancer. It contains an antibody linked to a toxic… »
A substance being studied in the treatment of myeloid leukemia (a disease in which too many immature non-lymphocyte white blood cells are… »
A plasmid DNA encoding the A chain of the diphtheria toxin (DT-A) driven by the transcriptional regulatory sequences of human H19, with… »
An anticancer drug formed by the combination of diphtheria toxin and a colony-stimulating factor (GM-CSF). The colony-stimulating factor is attracted to cancer… »
An inflammatory response that develops 24 to 72 hours after exposure to an antigen that the immune system recognizes as foreign. This… »
A regimen consisting of cisplatin, dacarbazine and carmustine used for the treatment of advanced-stage or metastatic malignant melanoma. »
A drug that is used to treat Hodgkin lymphoma and malignant melanoma and is being studied in the treatment of other types… »
Medicamento que se usa para tratar el linfoma de Hodgkin y el melanoma maligno; está en estudio para el tratamiento de otros… »
Human DTL wild-type allele is located in the vicinity of 1q32 and is approximately 72 kb in length. This allele, which encodes… »
This gene is involved in signal transduction and regulation of transcription. It also plays a role in development. »
Human DTX1 wild-type allele is located in the vicinity of 12q24 and is approximately 40 kb in length. This allele, which encodes… »
Human DTX2 wild-type allele is located in the vicinity of 7q11.23 and is approximately 44 kb in length. This allele, which encodes… »
A cell line made from human prostate cancer cells that is used in the laboratory to study the way prostate cancer cells… »
Línea celular elaborada con células cancerosas de la próstata humana que se usa en el laboratorio para estudiar la manera en que… »
An orally available inhibitor of receptor tyrosine kinases anaplastic lymphoma kinase (ALK) and the epidermal growth factor receptor (EGFR) with potential antineoplastic… »
A heart pacemaker with the capability of monitoring and stimulating both the atria and/or the ventricles when necessary. »
A pump system with two enclosed reservoirs, designed to deliver various concentrations of intravenous contrast media. »
A person with dual diagnosis has both a mental disorder and an alcohol or drug problem. These conditions occur together frequently. In… »
An imaging test that measures bone density (the amount of bone mineral contained in a certain volume of bone) by passing x-rays… »
An oral small molecule inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (InsR) tyrosine kinases with potential antineoplastic… »
A dosing unit equal to the amount of active ingredient(s) in a product containing two individual units. »
An orally available agent targeting phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) kinase in the PI3K/mTOR signaling pathway, with… »
An agent targeting the phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in the PI3K/mTOR signaling pathway, with potential antineoplastic… »
Dual specificity mitogen-activated protein kinase kinase 1 (393 aa, ~43 kDa) is encoded by the human MAP2K1 gene. This protein plays a… »
Dual specificity mitogen-activated protein kinase kinase 2 (400 aa, ~44 kDa) is encoded by the human MAP2K2 gene. This protein plays a… »
Dual specificity mitogen-activated protein kinase kinase 4 (399 aa, ~44 kDa) is encoded by the human MAP2K4 gene. This protein is involved… »
Dual specificity mitogen-activated protein kinase kinase 6 (334 aa, ~37 kDa) is encoded by the human MAP2K6 gene. This protein plays a… »
Dual specificity protein kinase TTK (857 aa, ~97 kDa) is encoded by the human TTK gene. This protein is involved in mitotic… »
Dual specificity protein phosphatase 1 (367 aa, ~39 kDa) is encoded by the human DUSP1 gene. This protein plays a role in… »
Dual specificity protein phosphatase 22 (184 aa, ~22 kDa) is encoded by the human DUSP22 gene. This protein is involved in both… »
Dual specificity protein phosphatase 3 (185 aa, ~20 kDa) is encoded by the human DUSP3 gene. This protein plays a role in… »
Dual specificity protein phosphatase 4 (394 aa, ~43 kDa) is encoded by the human DUSP4 gene. This protein is involved in the… »
Dual specificity protein phosphatase 5 (384 aa, ~42 kDa) is encoded by the human DUSP5 gene. This protein is involved in the… »
Dual specificity protein phosphatase 6 (381 aa, ~42 kDa) is encoded by the human DUSP6 gene. This protein plays a role in… »
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (763 aa, ~86 kDa) is encoded by the human DYRK1A gene. This protein is involved in the… »
An imaging test that measures bone density (the amount of bone mineral contained in a certain volume of bone) by passing x-rays… »
Dual-specificity protein phosphatases are a subclass of protein tyrosine phosphatases that are uniquely able to hydrolyse the phosphate ester bond on both… »
A scan which acquires 2 acquisitions of the same regions some time apart. »
A rare disorder affecting the muscles of the eye. It is characterized by an abnormal contraction of some eye muscles and failure… »
An inherited autosomal recessive disorder characterized by the presence of mild jaundice due to abnormalities in the bilirubin transportation from the liver… »
The formula to calculate body surface area as described by D and EF DuBois. It is mathematically defined as: BSA (m^2) =… »
An anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Duborimycin exhibits cytotoxic activity through topoisomerase-mediated interaction with DNA,… »
The numerical value that represents a clinical assessment of neurological and physical criteria, performed between birth and five days of age, to… »
An X-linked inherited disorder caused by mutations in the DMD gene found on the X chromosome. It is characterized by rapidly progressing… »
A device structure designed to channel the movement of gas or liquid. »
An embryonic remnant of the mesonephric duct in females that runs parallel to the uterus, cervix and vagina. »
A convoluted tube connecting the efferent ductules of the testicle to the vas deferens. »
The portion of the salivary system that conveys the saliva produced in the acinar salivary gland system to the oral cavity. The… »
A breast carcinoma arising from the ducts. While ductal carcinomas can arise at other sites, this term is universally used to… »
A carcinoma entirely confined to the mammary ducts. It is also known as DCIS. There is no evidence of invasion… »
A breast carcinoma characterized by the presence of a ductal carcinoma in situ component and an invasive lobular carcinomatous component. »
The co-existence of ductal and lobular carcinoma in situ in the breast, without evidence of stromal invasion. »
A ductal carcinoma in situ of the breast in which the tumor cells fill the ductal spaces as solid sheets. »
An invasive breast carcinoma characterized by the presence of a predominant squamous cell component that is admixed with the ductal carcinomatous… »
Hyperplasia of the epithelial cells in the breast ducts. It includes the atypical ductal hyperplasia, papillary intraductal hyperplasia, intraductal myoepitheliosis, and ductal… »
The most common type of breast cancer. It begins in the lining of the milk ducts (thin tubes that carry milk from… »
A noninvasive condition in which abnormal cells are found in the lining of a breast duct. The abnormal cells have not spread… »
A stratified columnar epithelial cell that surrounds a lumen in a gland such as the breast, pancreas or prostate. These cells are… »
A mammary gland with reduced numbers of ducts. »
A condition in which abnormal cells are found in the lining of a breast duct (milk duct). Having ductal intraepithelial neoplasia may… »
A method used to collect cells from milk ducts in the breast. A hair-size catheter (tube) is inserted into the nipple, and… »
Focal dysmorphogenesis of ducts leading to a proliferation of atypical cells in the terminal ducts and/or the collecting ducts »
A morphologic finding indicating the presence of typical or atypical proliferation of biliary epithelial cells in the portal tracts of the… »
A congenital disorder of the intrahepatic bile ducts characterized by abnormal embryonal development of the ductal plates. »
A procedure that uses x-rays to create pictures of milk ducts in the breast. A very thin catheter (tube) is inserted into… »
A morphologic finding indicating reduction in the numbers of interlobular and septal bile ducts in the liver tissue. »
An accessory pancreatic duct with two branches, one of which opens directly to the duodenum at the minor duodenal papilla while the… »
A vein occurring during embryonic development that is the continuation of the left umbilical vein that drains into the inferior vena… »
Congenital absence of the fetal ductus venosus. »
The date (and time) on which the activity or event is expected or scheduled to be submitted. »
Duffy antigen/chemokine receptor (336 aa, ~36 kDa) is encoded by the human DARC gene. This protein is involved in cytokine binding. … »
The Duke Cancer Institute is dedicated to a broad spectrum of cancer research and the translation of that research into the latest… »
Cancer has spread from the mucosa (innermost layer) of the colon and/or rectal wall to the submucosa (layer of tissue under the… »
Cancer has spread (1) through the muscle layer of the colon and/or rectal wall to the serosa (outermost layer) of the colon… »
Cancer (1) may have spread through the mucosa (innermost layer) of the colon and/or rectal wall to the submucosa (layer of tissue… »
A staging system used to describe the extent of colorectal cancer. Stages range from A (early stage) to D (advanced stage). … »
A staging system used to describe the extent of colorectal cancer. Stages range from A (early stage) to D (advanced stage). … »
A recombinant human soluble protein corresponding to amino acids 114-281 of the Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand (RhApo2L/TRAIL) with potential antineoplastic… »
A fibrate derivative with antilipidemic activity. Unlike clofibrate, dulofibrate is selective for a reduction in triglycerides. »
Medicamento que se usa para tratar la depresión y la neuropatía periférica (dolor, adormecimiento, cosquilleo, ardor, o debilidad en las manos o… »
A drug used to treat depression and peripheral neuropathy (pain, numbness, tingling, burning, or weakness in the hands or feet) that can… »
A drug used to treat depression and peripheral neuropathy (pain, numbness, tingling, burning, or weakness in the hands or feet) that can… »
A simple electronic device used for testing purposes designed to draw the same current as a complex device. »
A outflow valve designed to quickly empty a system. »
A condition that occurs when food or liquid moves too fast into the small intestine. Symptoms include cramps, nausea, diarrhea, sweating, weakness,… »
Albino outbred guinea pig belonging to the English (short-haired) breed. The Dunkin Hartley guinea pig is a crepuscular mammalian herbivore that is… »
The Dun and Bradstreet D-U-N-S Number is a non-indicative, nine-digit number assigned to each business location in the D&B database having a… »
A spirocyclopropylhexadienone-containing antineoplastic antibiotic isolated from Streptomyces bacterial species or derived synthetically. Duocarmycin antibiotics alkylate DNA by binding to adenine-thymine (A-T)- rich… »
An adenocarcinoma that arises from the duodenum. Histologic variants include mucinous adenocarcinoma and signet ring cell carcinoma. »
A circumscribed neoplasm that arises from the glandular epithelium of the duodenum. Morphologically, it is characterized by a proliferation of neoplastic glandular… »
A congenital malformation characterized by the absence of a normal opening in a part of the duodenum. »
A pathologic fibrous band that impedes passage of intestinal contents through the duodenum. »
A carcinoma that arises from the duodenum. The vast majority of cases are adenocarcinomas. »
An extraskeletal osteosarcoma affecting the duodenum. »
An abnormal communication between the duodenum and another organ or cavity. »
A gastrin-producing neuroendocrine tumor that arises from the duodenum. It is characterized by the presence of uniform cells that form… »
Bleeding originating from the duodenum. »
An infectious process affecting the duodenum. »
A benign or malignant neoplasm that affects the wall of the duodenum. Representative examples include adenoma, carcinoma, and lymphoma. »
A well differentiated, low grade neuroendocrine tumor (carcinoid tumor) that arises from the duodenum. The mitotic count is less than 2… »
Blockage of the normal flow of stomach contents through the duodenum. »
A rupture in the duodenal wall due to traumatic or pathologic processes. »
A somatostatin-producing neuroendocrine tumor that arises from the duodenum. It is characterized by the presence of tubulo-glandular structures. »
Narrowing of the lumen of the duodenum. »
An ulcer in the duodenal wall. »
A neoplasm that arises from the glandular epithelium of the duodenum. It is characterized by a villous architectural pattern. The neoplastic glandular… »
Partial or complete obstruction of the duodenal lumen due to the presence of a membranous web. »
Surgical removal of part or all of the duodenum. »
Inflammation of the duodenum (the first part of the small intestine that connects to the stomach). »
Inflamación del duodeno (la primera parte del intestino delgado que se conecta con el estómago). »
Primera parte del intestino delgado. Se conecta con el estómago. El duodeno ayuda a seguir digiriendo los alimentos que vienen del… »
The first part of the small intestine. It connects to the stomach. The duodenum helps to further digest food coming from the… »
A clinical finding about one or more characteristics of duodenum/ampulla/jejunum/ileum neuroendocrine tumor, following the rules of the TNM AJCC v7 classification system… »
A pathologic finding about one or more characteristics of duodenum/ampulla/jejunum/ileum neuroendocrine tumor, following the rules of the TNM AJCC v7 classification system… »
A pathologic finding about one or more characteristics of duodenum/ampulla/jejunum/ileum neuroendocrine tumor, following the rules of the TNM AJCC v7 classification system… »
A congenital abnormality of the kidney characterized by the presence of two separate pelvicocaliceal systems with a single or duplex ureter. … »
An electronic switching device that allows an antenna to be used for both transmitting and receiving. »
A congenital abnormality characterized by the presence of two separate ureters draining a kidney. »
The tough outer layer of tissue that covers and protects the brain and spinal cord and is closest to the skull. The… »
A type of power of attorney. A power of attorney is a legal document that gives one person (such as a relative,… »
A rare, primary marginal zone lymphoma of mucosa-associated lymphoid tissue that arises from the meningeal dura. The majority of cases have… »
Venous channels within the dura mater of the brain which receives both blood from blood vessels within the brain as well as… »
La capa exterior de tejido fuerte que cubre y protege el cerebro y la médula espinal que se encuentra más cerca del… »
The amount of time elapsed during the administration of an agent. »
The interval of time over which a course of doses occurs. »
Duration from rupture of membranes to birth (in hours and minutes). »
The amount of time that a thing is consumed or employed. »
The length of time from the beginning to the end of a single uterine contraction during the labor and childbirth process. … »
A commercial combination preparation, by Biovail Pharmaceuticals, containing chlorpheniramine maleate, phenylephrine hydrochloride and methscopolamine nitrate used to relieve symptoms of cold and… »
Within a certain period of time or after a certain point or period in time. »
An older breed of American domestic pig, the Duroc breed is of medium length with a muscular, large-framed body. This pig breed… »
A drug used to treat urothelial carcinoma (a type of bladder cancer) that has advanced or spread to other parts of the… »
A finding indicating the presence of dark discoloration on the mucosal surface. It is associated with tissue necrosis. »
This gene is a transcriptional target of TP53 protein and plays a role in cell cycle regulation. »
Human DUSP1 wild-type allele is located within 5q34 and is approximately 3 kb in length. This allele, which encodes dual specificity protein… »
This gene is involved in the inactivation of proteins which participate in cellular differentiation and proliferation. »
Human DUSP22 wild-type allele is located in the vicinity of 6p25.3 and is approximately 59 kb in length. This allele, which encodes… »
This gene plays a role in the inactivation of proteins involved in cellular differentiation and proliferation. »
Human DUSP3 wild-type allele is located with 17q21 and is approximately 13 kb in length. This allele, which encodes dual specificity protein… »
This gene is involved in the dephosphorylation of MAPK1 and MAPK3. »
Human DUSP4 wild-type allele is located within 8p12-p11 and is approximately 18 kb in length. This allele, which encodes dual specificity protein… »
This gene is involved in the dephosphorylation of ERK family proteins. »
Human DUSP5 wild-type allele is located in the vicinity of 10q25 and is approximately 14 kb in length. This allele, which encodes… »
This gene plays a role in MAP kinase dephosphorylation. »
Human DUSP6 wild-type allele is located within 12q22-q23 and is approximately 6 kb in length. This allele, which encodes dual specificity protein… »
A powder intended to be dusted over the outer surface of the body. »
Medicamento usado para tratar síntomas de agrandamiento de la glándula prostática. Está en estudio para el tratamiento de la pérdida de cabello… »
A drug used to treat symptoms of an enlarged prostate gland. It is being studied in the treatment of male hair loss… »
A smaller sized lagomorph, the Dutch belted rabbit has black hindquarters, ears and black patches around the eyes while the feet, face,… »
A potent, water soluble, selective and orally bioavailable, boronic acid-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Dutogliptin irriversibly binds… »
The tartrate salt form of dutogliptin, a potent, water soluble, selective and orally bioavailable, boronic acid-based inhibitor of dipeptidyl peptidase 4 (DPP-4),… »
Human DUX4 wild-type allele is located in the vicinity of 4q35 and is approximately 2 kb in length. This allele, which encodes… »
A regimen consisting of liposomal doxorubicin, vincristine and dexamethasone used as induction therapy for multiple myeloma. »
The formation of a blood clot in a deep vein of the leg or lower pelvis. Symptoms may include pain, swelling, warmth,… »
Short stature that usually results from genetic mutations. Other causes include hormonal deficiencies and poor nutrition. »
Medicamento contra el cáncer que es un tipo de antibiótico antitumoral. Es una antraciclina. »
An anticancer drug that is a type of topoisomerase inhibitor. Also called exatecan mesylate. »
Medicamento contra el cáncer que es un tipo de inhibidor de la topoisomerasa. También se llama exatecán mesilato. »
An imaging test that measures bone density (the amount of bone mineral contained in a certain volume of bone) by passing x-rays… »
Prueba de imaginología que mide la densidad ósea (la cantidad de mineral óseo contenido en un cierto volumen de hueso) al pasar… »
Procedimiento para extraer tejido del canal cervical o del revestimiento interno del útero. El cuello uterino se dilata (se hace más grande)… »
An unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal… »
The hydrochloride salt of Dyclonine, an unclassified compound with local anesthetic effect. Dyclonine reversibly binds to activated sodium channels on the neuronal… »
Chemical substances that are used to stain and color other materials. The coloring may or may not be permanent. Dyes can also… »
A laser in which light is emitted by a fluorescent organic dye and which can be tuned to radiate at any of… »
A modification of contrast-enhanced MRI that allows observation of functional properties in addition to structural properties. »
A type of computer tomography whereby a contrast medium is administered intravenously or orally prior to X-ray imaging. »
A computer program that enables an application to define classes dynamically. »
A class created by the Dynamic Extension computer program. »
A scan using red light instead of x-rays to differentiate between benign and malignant conditions. It measures physiological changes in the breast… »
The largest difference between, or ratio of, an instrument's or method's highest and lowest value in a set, such as pixel (voxel)… »
Scan having a number of sequential frames. »
A type of computed tomography in which the patient is moved through the scanner continuously rather than in increments, so that the… »
Dynamin-2 (870 aa, ~98 kDa) is encoded by the human DNM2 gene. This protein plays a role in both microtubule polymerization and… »
A unit of force in the CGS system defined as the force that accelerates a mass of one gram at the rate… »
Dynein light chain roadblock-type 1 (96 aa, ~11 kDa) is encoded by the human DYNLRB1 gene. This protein plays a role in… »
An antitumor antibiotic of the enediyne class. It has demonstrated high DNA cleavage activity in the presence of NADPH, antimicrobial and tumor… »
An enediyne antineoplastic antibiotic hybrid containing an anthraquinone moiety isolated from the bacterium Micromonospora chersina. The anthraquinone moiety intercalates into DNA… »
This gene plays a role in intracellular transport. »
Human DYNLRB1 wild-type allele is located in the vicinity of 20q11.21 and is approximately 25 kb in length. This allele, which encodes… »
A xanthine derivative. Dyphilline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Dyphilline probably acts as a competitive… »
This gene is involved in both protein phosphorylation and signaling. »
Human DYRK1A wild-type allele is located in the vicinity of 21q22.13 and is approximately 148 kb in length. This allele, which encodes… »
Slow and slurred speech resulting from inability to coordinate the muscles that are used in speech. Causes include brain damage, Parkinson disease,… »
An acute or chronic disorder, affecting the sympathetic or parasympathetic nervous system. It can be primary, the result of central nervous… »
A wide group of related learning disorders characterized by difficulties with mathematics and manipulating numbers; the difficulty with math may be caused… »
A benign glial-neuronal neoplasm. It is usually supratentorial, located, generally, in the cortex and occurs in children and young adults with a… »
A condition in which a sense, especially touch, is distorted. Dysesthesia can cause an ordinary stimulus to be unpleasant or painful. It… »
Human DYSF wild-type allele is located in the vicinity of 2p13.3 and is approximately 233 kb in length. This allele, which encodes… »
Dysferlin (2080 aa, ~237 kDa) is encoded by the human DYSF gene. This protein plays a role in sarcolemmal membrane dynamics. … »
A state of not functioning normally. »
A type of tumor that begins in the type of cells that give rise to egg cells and is most often found… »
A rare genetic disorder characterized by nail dystrophy, reticulated skin pigmentation especially on the neck and chest, and oral leukoplakia. In… »
Difficulty moving; distortion or impairment of voluntary movement, as in tic, spasm, or myoclonus. »
A learning disorder characterized by an impairment in processing written words. Reading difficulties can include distortions, omissions or substitutions of characters. Oral… »
A lipoprotein metabolism disorder characterized by decreased levels of high-density lipoproteins, or elevated levels of plasma cholesterol, low-density lipoproteins and/or triglycerides. … »
Abnormally painful abdominal cramps during menstruation. »
Defective bone formation involving individual bones, singly or in combination. »
Painful or difficult coitus. »
An uncomfortable, often painful feeling in the stomach, resulting from impaired digestion. Symptoms include burning stomach pain, bloating, heartburn, nausea, and… »
A symptom referring to difficulty in swallowing. It may be observed in patients with stroke, motor neuron disorders, cancer of the throat… »
Trouble with the voice when trying to talk, including hoarseness and change in pitch or quality or voice. »
Epithelial dysplasia that develops in Barrett esophagus. It is classified as low or high grade. When technical reasons make the interpretation of… »
A morphologic finding indicating the presence of dysplastic epithelial changes in a large intestinal tissue sample that is affected by ulcerative… »
A term that refers to raised and dysplastic large intestinal lesions in patients with a history of ulcerative colitis. Grossly, these… »
A benign, WHO grade I cerebellar mass, which occurs in young adults and is composed of dysplastic ganglion cells. It is… »
A type of nevus (mole) that looks different from a common mole. A dysplastic nevus is often larger with borders that are… »
An autosomal dominant disorder defined by the presence of multiple dysplastic nevi and a history of melanoma in two family members. … »
Treatment to manage or alleviate difficult or painful breathing or shortness of breath. »
A disorder characterized by episodes of respiratory distress, usually occurring after several hours of sleep in a reclining position. It is most… »
Chronically depressed mood that occurs for most of the day more days than not for at least 2 years. The required minimum… »
A persistent attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most… »
Dystonin (7570 aa, ~860 kDa) is encoded by the human DST gene. This protein plays a structural role in cytoskeleton networks. … »
A rare autosomal dominant disorder caused by mutations in the DMPK gene. It is characterized by myotonia, muscular dystrophy, hypogonadism, heart conduction… »
A rare autosomal dominant disorder caused by mutations in the CNBP gene. It is characterized by muscle pain, fatigue, and weakness of… »
Dystrophin (3685 aa, ~427 kDa) is encoded by the human DMD gene. This protein is involved in anchoring the cytoskeleton to the… »
E-cadherin (882 aa, 97 kD) is a cell adhesion process protein that is encoded by the human CDH1 gene and has a… »
An immunohistochemical technique to detect E-Cadherin, a transmembrane glycoprotein that is localized in the adherens junctions of epithelial cells, using antibody to… »
A device that has the shape of a cigarette, cigar, or pen and does not contain tobacco. It uses a battery and… »
A regimen consisting of epirubicin, followed by cyclophosphamide, methotrexate, fluorouracil (CMF), used in the adjuvant setting for the treatment of breast… »
E-mail is short for "electronic mail" and refers to composing, sending, and receiving messages over electronic communication systems. Most e-mail systems use… »
A text string identifier for a location to which e-mail can be delivered. »
A chromatin-remodeling complex that contains the BRG1, BAF170, BAF155, and INI1 homologs of yeast SWI/SNF subunits, as well as a unique subunit,… »
Cell adhesion molecule and CD antigen that mediates neutrophil, monocyte, and memory T-cell adhesion to cytokine-activated endothelial cells. E-selectin recognizes sialylated carbohydrate… »
A system for naming the stereoisomers of a molecule. The configuration at each double bond is determined by the priority of the… »
Genetically-modified neural stem cells (NSCs) transfected with the Escherichia coli (E. coli) suicidal gene cytosine deaminase (CD), with potential antineoplastic adjuvant… »
E. coli is the name of a type of bacteria that lives in your intestines. Most types of E. coli are… »
E1A gene combined with lipids that serve as a means to deliver the E1A gene into the cancer cells. The combination of… »
Proteins transcribed from the E1A region of adenovirus which are involved in positive regulation of transcription of the early genes. (MSH2001) … »
Human E1B protein (175 aa, 20 kDa) protein is encoded by the human adenovirus 2 (HadV-2) gene. This protein is transcribed by… »
E2F-1 is a transcription factor that regulates the expression of genes involved in the cell cycle and that is involved in progression… »
A second-generation E2F1 pathway activator with potential antineoplastic activity. ARQ 171 induces the expression of E2F transcription factor 1, thereby activating the… »
Human E2F1 wild-type allele is located in the vicinity of 20q11.2 and is approximately 11 kb in length. This allele, which encodes… »
Human E2F2 wild-type allele is located in the vicinity of 1p36 and is approximately 25 kb in length. This allele, which encodes… »
This gene is involved in the regulation of both transcription and cell cycle progression. »
Human E2F3 wild-type allele is located in the vicinity of 6p22 and is approximately 147 kb in length. This allele, which encodes… »
Human E2F6 wild-type allele is located in the vicinity of 2p25.1 and is approximately 22 kb in length. This allele, which encodes… »
E3 SUMO-protein ligase CBX4 (558 aa, ~61 kDa) is encoded by the human CBX4 gene. This soluble, nuclear protein plays a role… »
E3 SUMO-protein ligase PIAS1 (651 aa, ~72 kDa) is encoded by the human PIAS1 gene. This protein is involved in the mediation… »
E3 Ubiquitin Ligases are ATP-dependent enzymes that catalyze the formation of a covalent bond between ubiquitous intracellular Ubiquitin proteins and other proteins,… »
E3 ubiquitin-protein ligase BRE1A (975 aa, ~114 kDa) is encoded by the human RNF20 gene. This protein plays a role in the… »
E3 ubiquitin-protein ligase CBL-B (982 aa, ~109 kDa) is encoded by the human CBLB gene. This protein plays a role in the… »
E3 ubiquitin-protein ligase CCNB1IP1 (277 aa, ~32 kDa) is encoded by the human CCNB1IP1 gene. This protein plays a role in both… »
E3 ubiquitin-protein ligase CHFR (664 aa, ~73 kDa) is encoded by the human CHFR gene. This protein is involved in both ubiquitination… »
E3 ubiquitin-protein ligase FANCL (375 aa, ~43 kDa) is encoded by the human FANCL gene. This protein is involved in the regulation… »
E3 ubiquitin-protein ligase makorin-1 (482 aa, ~53 kDa) is encoded by the human MKRN1 gene. This protein is involved in the ubiquitination… »
E3 ubiquitin-protein ligase MARCH9 (346 aa, ~38 kDa) is encoded by the human MARCH9 gene. This protein is involved in the ubiquitination… »
E3 ubiquitin-protein ligase MDM2 (491 aa, 55 kD) is encoded by the human MDM2 gene. This protein plays a role in negative… »
E3 ubiquitin-protein ligase MIB1 (1006 aa, ~110 kDa) is encoded by the human MIB1 gene. This protein is involved in both ubiquitination… »
E3 ubiquitin-protein ligase NEDD4 protein (1000 aa, ~115 kDa) is encoded by the human NEDD4 gene. This protein is involved in the… »
E3 ubiquitin-protein ligase parkin (465 aa, ~52 kDa) is encoded by the human PARK2 gene. This protein may play a role in… »
E3 ubiquitin-protein ligase RAD18 (495 aa, ~56 kDa) is encoded by the human RAD18 gene. This protein plays a role in both… »
E3 ubiquitin-protein ligase RNF130 (419 aa, ~46 kDa) is encoded by the human RNF130 gene. This protein is involved in post-translational protein… »
E3 ubiquitin-protein ligase RNF139 (664 aa, ~76 kDa) is encoded by the human RNF139 gene. This protein plays a role in protein… »
E3 ubiquitin-protein ligase RNF146 (359 aa, ~39 kDa) is encoded by the human RNF146 gene. This protein plays a role in the… »
E3 ubiquitin-protein ligase RNF43 (783 aa, ~86 kDa) is encoded by the human RNF43 gene. This protein is involved in the modulation… »
E3 ubiquitin-protein ligase SIAH2 (324 aa, ~35 kDa) is encoded by the human SIAH2 gene. This protein plays a role in the… »
E3 ubiquitin-protein ligase TRAF7 (670 aa, ~75 kDa) is encoded by the human TRAF7 gene. This protein is involved in both protein… »
E3 ubiquitin-protein ligase TRIM21 (475 aa, ~54 kDa) is encoded by the human TRIM21 gene. This protein is involved in both the… »
E3 ubiquitin-protein ligase TRIM33 (1127 aa, ~123 kDa) is encoded by the human TRIM33 gene. This protein is involved in protein… »
E3 ubiquitin-protein ligase TRIM36 (728 aa, ~83 kDa) is encoded by the human TRIM36 gene. This protein is involved in the regulation… »
E3 ubiquitin-protein ligase UBR5 (2799 aa, ~309 kDa) is encoded by the human UBR5 gene. This protein plays a role in the… »
E3 ubiquitin/ISG15 ligase TRIM25 (630 aa, ~71 kDa) is encoded by the human TRIM25 gene. This protein is involved in both innate… »
Has platelet storage disease associated with the red-eyed yellow locus, as described by Raymond and Dodds (1975) for the FH strain. … »
Lipidated cytotoxic T-cell epitopes of Human Papilloma Virus Type 16 E7 for use in Vaccine Therapy. »
A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called sulfonamides. »
A drug used to treat metastatic breast cancer in patients who have already been treated with other chemotherapy. It is also being… »
Medicamento que se usa para tratar el cáncer de mama metastásico de pacientes que ya fueron tratados con otra quimioterapia. También está… »
A cancer peptide vaccine comprised of a human leukocyte antigen (HLA) A2/A3 restricted HER2/neu (ERBB2) peptide (amino acids 366 to 379) from… »
A small molecule and aromatic sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a… »
Enfermedad en la que las arterias coronarias (vasos sanguíneos que llevan sangre y oxígeno al corazón) se estrechan o se impide el… »
Tipo de trastorno hereditario en el que hay problemas con la manera en que una forma de glucosa (azúcar) llamada glucógeno… »
Enfermero(a) diplomado que tiene estudios y capacitación adicionales para diagnosticar y tratar enfermedades. Los EAP tienen una licencia en el orden estatal… »
A sense organ needed for the detection of sound and for establishing balance. The outer ear consists of the auricle, the ear… »
Any deviation from the normal structure or function of the ear or labyrinth that is manifested by a characteristic set of symptoms… »
A carcinoma that arises from the ear. Representative examples include ceruminous adenocarcinoma and squamous cell carcinoma of the external ear and… »
A pit or dimple in front of the ear of a newborn is a common finding; rarely, such a dimple may get… »
A non-neoplastic or neoplastic disorder that affects the ear. Representative examples include infections, hearing disorders, benign neoplasms, and carcinomas. »
Your ear has three main parts: outer, middle and inner. You use all of them in hearing. Sound waves come in through… »
Symptoms, physical examination results, and/or laboratory test results related to the ear. »
A viral or bacterial infection that affects the external, middle, or inner ear. It may follow an upper respiratory infection. … »
Ear infections are the most common reason parents bring their child to a doctor. Three out of four children will have at… »
A benign or malignant neoplasm that affects the external, middle, or internal ear. Representative examples include ceruminous adenoma, polyp, and… »
Any component pertaining to the organ for hearing including the external, middle, and inner ear. »
Early activation antigen CD69 (199 aa, ~23 kDa) is encoded by the human CD69 gene. This protein plays a role in signal… »
A transitional time in an individual's life between childhood and adolescence. This phase marks the start of physical, physiological and psychological changes… »
A time period in a child's life that is accepted to be approximately between 1 and 5 years of age. »
Use of a device, marker, or other means for the purpose of detecting the presence of a tumor early in its… »
Development of scientific information and concepts, and dissemination of knowledge regarding early detection techniques, practices, and strategies to reduce mortality and morbidity… »
Established by NCI to identify and evaluate molecular biomarkers and technologies for earlier detection and risk assessment of all major cancers. The… »
Clinical studies testing the efficacy of devices, techniques, procedures, or tests for earlier diagnosis of disease. »
The endosomal compartment that fuses with endocytic vesicles and sorts the plasma membrane components from any internalized molecules that are targeted for… »
A clinical stage I or II non-Hodgkin lymphoma without any of the following risk factors: large mediastinal mass, extranodal spread, elevated erythrocyte… »
Death of a fetus at 10 weeks, 0 days to 15 weeks, 6 days of gestation. »
A gradual decrease in the fetal heart rate and return to baseline that is associated with a uterine contraction. The nadir of… »
An invasive adenocarcinoma confined to the mucosa or mucosa and submucosa of the gastric wall. The regional lymph nodes may or… »
Early growth response protein 1 (543 aa, ~58 kDa) is encoded by the human EGR1 gene. This protein is involved in the… »
A low grade, well-differentiated, early stage hepatocellular carcinoma. Grossly, it usually presents as a nodular lesion that measures less than 2… »
A cervical adenocarcinoma with minimal stromal invasion. The risk of local lymph node metastasis is insignificant and the prognosis is excellent. … »
A cervical squamous cell carcinoma with minimal stromal invasion. The risk of lymph node metastasis is low. »
A condition in which the ovaries stop working and menstrual periods stop before age 40. Natural menopause usually occurs around age… »
The early stages in the recuperation process of a mother after her pregnancy and delivery. »
Pregnancy loss before 10th week of gestation with no documentation of whether or not an embryo was visible on ultrasonogram. »
A characteristic complaint in a fertile woman that is indicative of a pregnancy. »
An electrocardiographic finding where the amplitude of the R wave becomes greater than the amplitude of the S wave in the QRS… »
Early reconstitution of a lost or injured part. »
An electrocardiographic finding of J point and ST segment elevation in the absence of other signs of acute ischemia or pericarditis. … »
A clinical stage I or II non-Hodgkin lymphoma with at least one of the following risk factors: large mediastinal mass, extranodal spread,… »
Early yaws includes primary and secondary stages of yaws, endemic tropical treponemal nonvenereal infection: development of initial lesion at inoculation site followed… »
Breast cancer that has not spread beyond the breast or the axillary lymph nodes. This includes ductal carcinoma in situ and stage… »
Breast carcinoma that has not spread beyond the breast and the axillary lymph nodes. »
A term used to describe cancer that is early in its growth, and may not have spread to other parts of the… »
The portion of the annual ring produced early in the growing season, characterized by large, thin-walled cells. Earlywood is more porous than… »
An earthquake happens when two blocks of the earth suddenly slip past one another. Earthquakes strike suddenly, violently, and without warning… »
A question about how easy or difficult it is to plan when to use a medication each time. »
A question about how easy or difficult it is to use a medication in its current form. »
A question about whether an individual is or was easily fatigued. »
One of the four primary cardinal directions. East is at 90 degree on a compass card. It is the direction of the… »
The essential oil of Cymbopogon flexuosus. East Indian lemongrass oil has antifungal activity. »
A census division of the United States consisting of Illinois, Indiana, Michigan, Ohio, and Wisconsin. »
A census division of the United States consisting of Alabama, Kentucky, Mississippi, and Tennessee. »
A cooperative group funded primarily by the NCI, one of the largest clinical cancer research organizations in the US, incorporating universities, medical… »
Eastern Cooperative Oncology Group (ECOG) Performance Status (Oken MM, Creech RH, Tormey DC, Horton J, Davis TE, McFadden ET, Carbone PP. Toxicity… »
Denotes a person having origins in any of the countries of Eastern Europe such as Czechoslovakia, Poland, Croatia, Hungary, Slovenia, Former Soviet… »
A religious group whose beliefs are based on the practices defined by the first seven ecumenical councils and whose members are located… »
A type of evergreen tree with hard fragrant wood that is a member of the cypress family. The oil from the wood… »
Bleeding that is disproportionate to the offending trauma. »
A broad group of psychological disorders with abnormal eating behaviors leading to physiological effects from overeating or insufficient food intake. »
Eating disorders are serious behavior problems. They can include severe overeating or not consuming enough food to stay healthy. They also involve… »
Human EBF1 wild-type allele is located in the vicinity of 5q34 and is approximately 401 kb in length. This allele, which encodes… »
A genus of filamentous, enveloped viruses with glycoprotein surface spikes, in the family Filoviridae. The genome is composed of a linear single-strand… »
A organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent… »
An oral capsule containing a proprietary formulation of the organoselenium compound ebselen, with potential anti-oxidant, anti-inflammatory and cytoprotective activity. Upon oral administration… »
A rare congenital heart malformation characterized by apical displacement of the opening of the tricuspid valve. The defect involves both the right… »
A common virus that remains dormant in most people. It causes infectious mononucleosis and has been associated with certain cancers, including Burkitt… »
An Epstein-Barr virus-associated mature T-cell lymphoproliferative group of disorders affecting children. It occurs with increased frequency in Asians and Native… »
A white blood cell that is derived from a lymphocyte stem cell matured in the thymus and characterized by a CD8 marker… »
A B-lymphocyte that has been activated to be receptive to Epstein Barr virus and is found in the area of a lymph… »
A regimen consisting of epirubicin and cyclophosphamide used in the adjuvant setting and also for the treatment of recurrent and metastatic breast… »
A regimen consisting of etoposide and carboplatin used for the treatment of extensive-stage small cell lung cancer. »
The determination of the activity of thrombin inhibitors in a biological specimen based on the generation of meizothrombin. »
Grupo de afecciones en las que la piel se inflama, se le forman ampollas y se vuelve costrosa, gruesa y con… »
The amount that the earth's revolution deviates from a circular path; the variation of an ellipse from a circle, where a circle… »
The determination of the amount of eccentrocytes present in a sample. »
A very rare, slow growing, usually asymptomatic hamartomatous lesion that arises from ectopic notochordal tissue. Morphologically it is characterized by the… »
A small bruise caused by blood leaking from broken blood vessels into the tissues of the skin or mucous membranes. »
A rare, congenital skin lesion consisting of a proliferation of eccrine glands with a vascular stroma. It presents as a flesh-colored, hyperhidrotic,… »
An adenocarcinoma with eccrine differentiation arising from the sweat glands. It includes the following subtypes: ductal eccrine adenocarcinoma, papillary eccrine carcinoma, and… »
A secretory cell that discharges its product without loss of cytoplasm. »
A type of simple sweat gland that is found in almost all regions of the skin. These glands produce sweat that reaches… »
A carcinoma with eccrine differentiation arising from the sweat glands. It may arise de novo or as a malignant transformation of a… »
An unbranched, coiled, tubular gland not associated with the hair follicle that promotes cooling by evaporation of its secretion. It is innervated… »
A hamartoma characterized by localized eccrine sweat gland malformation. »
A regimen consisting of epirubicin, cisplatin and fluorouracil used alone or with radiation for the treatment of advanced-stage gastric cancer. »
A line graph that shows changes in the electrical activity of the heart over time. It is made by an instrument called… »
Línea gráfica que muestra cambios en la actividad eléctrica del corazón durante cierto tiempo. Lo traza un instrumento que se… »
Measurements or calculations on measurements obtained from electrocardiographic tracings. »
An herb native to North America that has been used to prevent and treat the common cold and other respiratory infections. Echinacea… »
An over-the-counter herbal remedy, extracted from North American herb purple coneflower belonging to the Family Asteraceae, with potential immunostimulating and anti-inflammatory… »
A parasitic infection caused by tapeworm larvae of Echinococcus. It affects livestock and humans. It is characterized by the formation of hydatid… »
Echinoderm microtubule-associated protein like 4 (981 aa, ~109 kDa) is encoded by the human EML4 gene. This protein may play a role… »
A polypeptide quinoxaline antineoplastic antibiotic isolated from the bacterium Streptomyces echinatus. Echinomycin intercalates into DNA at two locations simultaneously in a… »
The time in milliseconds between the application of the excitation pulse and the recording of the peak echo signal. »
A type of Magnetic Resonance Imaging that uses only one nuclear spin excitation per image and therefore can obtain images in a… »
An image of the heart produced by ultrasonography. »
A procedure that uses ultrasonic waves directed over the chest wall to obtain a graphic record of the heart's position, motion of… »
A symptom of neurologic or psychiatric dysfunction in which the individual involuntarily and meaninglessly repeats a recently heard word, series of words,… »
The iodide salt form of echothiophate, a long-acting cholinesterase inhibitor with parasympathomimetic activity. Echothiophate iodide potentiates the action of endogenous acetylcholine by… »
A species of non-enveloped, spherical and icosahedral viruses in the Picornaviridae family and Enterovirus genus. The genome is composed of single-stranded, positive-sense… »
Human ECI2 wild-type allele is located in the vicinity of 6p24.3 and is approximately 20 kb in length. This allele, which encodes… »
A potentially life-threatening pregnancy-related disorder characterized by tonic-clonic seizures in association with hypertension after the twentieth week of gestation and up to… »
The apparent path of the sun on the celestial sphere, also used for the plane in which the motion of the earth… »
Examen físico de la mama realizada por un proveedor de atención de la salud para verificar la presencia de nódulos u otros… »
The extracellular matrix (ECM) consists of a complex mixture of structural and functional macromolecules and serves an important role in tissue and… »
Procedimiento en el que se usan ondas ecográficas dirigidas a la pared del pecho para obtener un registro gráfico de la posición… »
Eastern Cooperative Oncology Group (ECOG) Performance status. »
A performance status scale designed to assess disease progression and its affect on the daily living abilities of the patient. »
Fully active, able to carry on all pre-disease performance without restriction. »
Restricted in physically strenuous activity but ambulatory and able to carry out work of a light or sedentary nature, e.g., light house… »
Ambulatory and capable of all self care but unable to carry out any work activities. Up and about more than 50% of… »
Capable of only limited selfcare, confined to bed or chair more than 50% of waking hours. »
Completely disabled. Cannot carry on any selfcare. Totally confined to bed or chair. »
A question associated with the ECOG performance status questionnaire. »
Procedimiento en el que se usan ondas de sonido de alta energía para observar los tejidos y órganos del cuerpo. Las ondas… »
Procedimiento que se usa para examinar los órganos del abdomen. Se presiona firmemente contra la piel del abdomen un transductor… »
Procedimiento para detectar las áreas corporales en las que las células se multiplican rápidamente. Se utiliza para localizar células cancerosas o áreas… »
Procedimiento en el cual se inserta en el recto una sonda que emite ondas sonoras de alta energía. Las ondas sonoras rebotan… »
Procedimiento en el que se introduce un endoscopio en el cuerpo. Un endoscopio es un instrumento en forma de tubo delgado con… »
Procedimiento en el que se usan ecos (ondas sonoras de alta energía que se hacen rebotar en los tejidos y órganos internos… »
Procedimiento que se usa para examinar los órganos del abdomen. Se presiona firmemente contra la piel del abdomen un transductor… »
Procedimiento en el cual se inserta en el recto una sonda que emite ondas sonoras de alta energía. Las ondas sonoras rebotan… »
Procedimiento usado para examinar la vagina, el útero, las trompas de Falopio, los ovarios y la vejiga. Se inserta un instrumento en… »
Imagen en una computadora de áreas internas del cuerpo creadas por ondas sonoras de alta energía. Las ondas sonoras rebotan en los… »
A study that compares large groups of people instead of individuals for differences in things such as cancer rates. The groups can… »
Estudio mediante el que se comparan grupos grandes de personas, en vez de individuos, para determinar las diferencias de cosas tales como… »
A study that compares large groups of people instead of individuals for differences in things such as cancer rates. The groups can… »
The branch of biology concerned with the relations between organisms and their environment. »
A water-soluble nitrosoureido sugar derived from acosamine, with alkylating activity. Ecomustine alkylates and crosslinks DNA, thereby inhibiting replication and transcription and eventually… »
An imidazole with antifungal property. Econazole compromises the integrity of fungal cell wall through inhibiting 14-alpha demethylase, which catalyzes conversion of lanosterol… »
An imidazole derivative and broad-spectrum antimycotic agent with fungistatic properties. Econazole nitrate inhibits biosynthesis of ergosterol, thereby damaging the fungal cell wall… »
An indole inhibitor of cytosolic phospholipase A2alpha (cPLA2alpha, type IVA phospholipase) with antiinflammatory activity. »
A low-fucose, human-mouse chimeric IgG1 monoclonal antibody with potential antineoplastic activity targeting at the ganglioside GD3, a surface antigen expressed on many… »
A treatment for severe depression and certain mental disorders. A brief seizure is induced by giving electrical stimulation to the brain through… »
Human ECT2 wild-type allele is located within 3q26.1-q26.2 and is approximately 71 kb in length. This allele, which encodes protein ECT2, is… »
This gene may be involved in guanine nucleotide exchange. »
Human ECT2L wild-type allele is located in the vicinity of 6q24.1 and is approximately 108 kb in length. This allele, which encodes… »
Terminology developed to support eCTD Applicant Contact Types. »
Terminology developed to support eCTD Application Types. »
Terminology developed to support eCTD Form Types. »
Terminology developed to support eCTD Product Name Types. »
Terminology developed to support eCTD Promotional Promotional Material Audience Types. »
Terminology developed to support eCTD Promotional Material Document Types. »
Terminology developed to support eCTD Promotional Material Types. »
Terminology developed to support eCTD Submission Sub-Types. »
Terminology developed to support eCTD Submission Types. »
Terminology developed to support eCTD Supplemental Effect Date Types. »
Terminology developed to support eCTD Telephone Number Types. »
A substance that comes from a type of sea squirt and is being studied in the treatment of cancer. It binds to… »
Sustancia que se obtiene de un tipo de invertebrado marino que se llama ascidia y que está en estudio para el tratamiento… »
Having to do with the part of the cervix that protrudes into the vagina and is lined with epithelial cells. »
Relacionado con la parte del cuello uterino que sobresale hasta la vagina y está revestida con células epiteliales »
Removal of tissue from the ectocervix for microscopic examination. »
The mucous covering of the vaginal portion of the cervix. It is composed of epithelium, basement membrane, lamina propria mucosae, and lamina… »
The cervical opening on the side of the vagina. »
A flat, scale-like epithelial cell that lines the vaginal portion of cervix. »
Having to do with the part of the cervix that protrudes into the vagina and is lined with epithelial cells. »
The outermost germ layer of cells derived from the inner cell mass of the blastocyst; gives rise to the nervous system, sensory… »
An embryonic cell of the outer layer of three germ layers. These cells give rise to the epidermis and neural tissue. … »
A group of inherited disorders characterized by malformations of the structures that derive from the ectoderm, such as hair, teeth, nails and… »
A rare, fast-growing tumor of the nervous system or soft tissue that occurs in children and young adults. Ectomesenchymomas may form in… »
Tumor poco frecuente y de crecimiento rápido del sistema nervioso o del tejido blando que se presenta en niños y adultos… »
Tumor poco frecuente y de crecimiento rápido del sistema nervioso o del tejido blando que se presenta en niños y adultos… »
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (863 aa, ~99 kDa) is encoded by the human ENPP2 gene. This protein plays a role in… »
A rare congenital anomaly where the heart is formed outside of the thoracic cavity. It is associated with intracardiac lesions and other… »
A syndrome characterized by abnormal secretion of adrenocorticotrophic hormone in conjunction with neoplastic growth occurring anywhere in the body. The most common… »
A syndrome characterized by abnormal secretion of aldosterone in conjunction with neoplastic growth occurring anywhere in the body. »
An electrocardiographic finding of a regular atrial rhythm with atrial rate of less than 101 beats per minute which does not originate… »
A disorder characterized by an electrocardiographic finding of atrial tachycardia that does not originate from the sinoatrial node. »
A syndrome characterized by abnormal secretion of calcitonin in conjunction with neoplastic growth occurring anywhere in the body. »
A thymoma that arises in the cervical region and is not connected with the thymus gland. »
A syndrome characterized by abnormal secretion of chorionic gonadotropin in conjunction with neoplastic growth occurring anywhere in the body. »
Expression in an abnormal part of the body »
A syndrome characterized by abnormal secretion of growth hormone in conjunction with neoplastic growth occurring anywhere in the body. »
A benign, well circumscribed tumor of the neck occurring in adults. It is characterized by the presence of spindle cells, epithelial… »
Abnormal secretion of hormones in conjunction with neoplastic growth occurring anywhere in the body. »
A syndrome characterized by abnormal secretion of parathyroid hormone in conjunction with neoplastic growth occurring anywhere in the body. »
A condition in which a fertilized egg grows outside of the uterus, usually in one of the fallopian tubes. Symptoms include sharp… »
A syndrome characterized by abnormal secretion of prolactin in conjunction with neoplastic growth occurring anywhere in the body. »
A syndrome characterized by abnormal secretion of renin in conjunction with neoplastic growth occurring anywhere in the body. »
An electrocardiographic finding of a rhythm originating above the ventricles at a site other than the sinoatrial node. »
An electrocardiographic finding of three or more consecutive complexes of ventricular origin. The QRS complexes are wide and have an abnormal… »
A congenital defect characterized by the absence or hypoplasia of one or more extremities. »
A monoclonal antibody used to prevent red blood cells from being destroyed in patients with paroxysmal nocturnal hemoglobinuria (PNH), a red blood… »
Anticuerpo monoclonal que se usa para prevenir la destrucción de glóbulos rojos en pacientes de hemoglobinuria paroxística nocturna (HNP), un trastorno de… »
A group of conditions in which the skin becomes inflamed, forms blisters, and becomes crusty, thick, and scaly. Eczema causes burning and… »
An agent belonging to the glitazone class of antidiabetic agents with antihyperglycemic activity. Edaglitazone also appears to lower triglyceride and free fatty… »
The sodium salt form of edaglitazone, an agent belonging to the glitazone class of antidiabetic agents with antihyperglycemic activity. Edaglitazone also appears… »
An anticancer drug that belongs to a family of drugs called antimetabolites. »
Medicamento contra el cáncer. Es un tipo de antimetabolito. »
Procedimiento que se usa para observar el interior del intestino delgado. Se introduce por la boca o el recto hacia el intestino… »
The determination of the amount of EDDP, the primary metabolite of methadone, present in a sample. »
A synthetic analog of lysophosphatidylcholine, an ether lipid, possessing anti-leishmanial and antineoplastic activity. The mechanism of action for edelfosine has not… »
Swelling due to an excessive accumulation of fluid in the upper or lower extremities. »
Acumulación de líquido en los alvéolos (espacios de aire) de los pulmones. Esto impide que el oxígeno llegue a la… »
Swelling due to an excessive accumulation of fluid in trunk area. »
Having teeth in neither the mandible nor the maxilla. »
Contracted name for a salt of ethylenediaminetetraacetate, an agent used as a chelator of lead and some other heavy metals. C10H12CaN2Na2O8. … »
The disodium salt form of edetate, a heavy metal chelating agent with anti-hypercalcemic and anti-arrhythmic properties. Edetate, a heavy metal antagonist, chelates… »
A chemical that binds certain metal ions, such as calcium, magnesium, lead, and iron. It is used in medicine to prevent blood… »
An artifact that occurs where different tissues meet. »
An edge artifact that results in image blurring. »
The type of change made to an element. »
A person who edits material for publication; a person having managerial and sometimes policy-making responsibility for the editorial part of a publishing… »
A self-report assessment tool to screen for the intensity of nine symptoms commonly experienced by cancer patients in palliative care. »
Human EDN1 wild-type allele is located in the vicinity of 6p24.1 and is approximately 7 kb in length. This allele, which encodes… »
Human EDN2 wild-type allele is located in the vicinity of 1p34 and is approximately 6 kb in length. This allele, which encodes… »
This gene plays a role in signal transduction. »
Human EDNRA wild-type allele is located in the vicinity of 4q31.23 and is approximately 64 kb in length. This allele, which encodes… »
This gene is involved in cell signaling. »
Human EDNRB wild-type allele is located in the vicinity of 13q22 and is approximately 24 kb in length. This allele, which encodes… »
A substance being studied in the treatment of cancer. It is a type of topoisomerase I inhibitor. Also called J-107088. »
Sustancia en estudio para el tratamiento de cáncer. Es un tipo de inhibidor de la topoisomerasa. También se llama J-107088. »
A chelated octreotide derivative with somatostatin activity. Edotreotide is produced by substituting tyrosine for phenylalanine at the 3 position of octreotide and… »
An orally active inhibitor of coagulation factor Xa (activated factor X) with anticoagulant activity. Edoxaban is administered as edoxaban tosylate. This agent… »
The tosylate salt form of edoxaban, an orally active inhibitor of coagulation factor Xa (activated factor X) with anticoagulant activity. Edoxaban is… »
A deoxythymidine analog with activity against herpes simplex virus. Edoxudine is activated by viral thymidine kinase to the 5'-monophosphate which is further… »
Un examen en el que el médico inserta un dedo enguantado y lubricado en el recto para palpar en busca de… »
A type of monoclonal antibody used in cancer detection or therapy. Monoclonal antibodies are laboratory-produced substances that can locate and bind to… »
Tipo de anticuerpo monoclonal que se usa para la detección o la terapia del cáncer. Los anticuerpos monoclonales son sustancias que se… »
The chloride salt form of edrophonium, a short and rapid-acting cholinesterase inhibitor with parasympathomimetic activity. Echothiophate chloride potentiates the action of endogenous… »
Kurtzke Expanded Disability Status Scale (EDSS) Expanded disability score. »
A question associated with the EDSS questionnaire. »
A chemical that binds certain metal ions, such as calcium, magnesium, lead, and iron. It is used in medicine to prevent blood… »
Sustancia química que se adhiere a los iones de ciertos metales como el calcio, magnesio, plomo e hierro. Se usa en medicina… »
A measurement of the volume of serum or plasma that would be cleared of Ethylenediamine tetraacetic acid (EDTA) through its excretion for… »
Educación acerca de los cambios de comportamiento y modos de vida para ayudar a los pacientes de enfermedad pulmonar crónica a disminuir… »
The activities of educating or instructing or teaching; activities that impart knowledge or skill. »
An indication of the years of schooling completed in graded public, private, or parochial schools, and in colleges, universities, or professional… »
A coded value specifying the highest level of education completed. »
Used in a wide variety of ways to promote an appreciation for and interest in biomedical research, provide additional training in specific… »
A class of professional or vocational positions of employment that involve education, training or libraries. »
The activities of educating or instructing or teaching; activities that impart knowledge or skill. »
An educational activity that is intended to prevent disease or alter the course of a disease in a patient or population. … »
A branch of psychology concerned with educational techniques and assessment of academic aptitude. »
A genetic disorder caused by having an extra chromosome 18 in some or all of the body’s cells. Edwards syndrome is marked… »
A genus of facultatively anaerobic, Gram negative, rod shaped bacterium assigned to the phylum Proteobacteria and the family Enterobacteriaceae. »
A species of facultatively anaerobic, Gram negative, rod shaped bacterium assigned to the phylum Proteobacteria. This species is motile by peritrichous flagella,… »
A species of facultatively anaerobic, Gram negative, rod shaped bacterium assigned to the phylum Proteobacteria. This species is nonmotile, indole, urease and… »
A species of facultatively anaerobic, Gram negative, rod shaped bacterium assigned to the phylum Proteobacteria. This species is motile by peritrichous flagella,… »
Procedimiento en el que se introduce un endoscopio en el cuerpo. Un endoscopio es un instrumento en forma de tubo delgado con… »
A regimen consisting of vincristine and doxorubicin, administered after nephrectomy and used for the treatment of limited-stage Wilm's tumor with a favorable… »
Human EED wild-type allele is located within 11q14.2-q22.3 and is approximately 34 kb in length. This allele, which encodes polycomb protein EED,… »
This gene plays a role in nucleotide binding and protein synthesis. »
Human EEF1A1 wild-type allele is located in the vicinity of 6q14.1 and is approximately 6 kb in length. This allele, which encodes… »
This gene is involved in nucleotide binding and protein translation. »
Human EEF1A2 wild-type allele is located in the vicinity of 20q13.3 and is approximately 11 kb in length. This allele, which encodes… »
Human EEF1B1 wild-type allele is located in the vicinity of 15q21.2 and is approximately 1 kb in length. This allele, a processed… »
This gene is involved in protein synthesis. »
Human EEF1B2 wild-type allele is located within 2q33-q34 and is approximately 3 kb in length. This allele, which encodes elongation factor 1-beta… »
Human EEF1B2P1 gene is located in the vicinity of 15q21.2 and is approximately 1 kb in length. The product is a processed… »
This gene plays a role in the synthesis of proteins. »
Human EEF1D wild-type allele is located in the vicinity of 8q24.3 and is approximately 18 kb in length. This allele, which encodes… »
This gene is involved in the synthesis of proteins. »
Human EEF1G wild-type allele is located in the vicinity of 11q12.3 and is approximately 14 kb in length. This allele, which encodes… »
Human EEF2 wild-type allele is located within 19pter-q12 and is approximately 9 kb in length. This allele, which encodes elongation factor 2… »
A recording of electrical activity in the brain. It is made by placing electrodes on the scalp (the skin covering the top… »
Registro de la actividad eléctrica del cerebro. Se realiza mediante la colocación de electrodos en el cuero cabelludo (la piel que cubre… »
A treatment being studied to improve brain function in certain brain disorders and in patients treated with chemotherapy for breast cancer. Sensors… »
Procedimiento para el que se usan pequeños impulsos eléctricos para estimular los músculos débiles o paralizados. Ayuda a aumentar la fuerza muscular,… »
Procedimiento para el que se usan pequeños impulsos eléctricos para estimular los músculos débiles o paralizados. Ayuda a aumentar la fuerza muscular,… »
Procedimiento en el cual se inserta en el recto una sonda que emite ondas sonoras de alta energía. Las ondas sonoras rebotan… »
Procedimiento que se usa para aplicar corrientes eléctricas de baja frecuencia en algunas áreas de la piel. También se llama estimulación eléctrica… »
A synthetic peptide derived from the protein ESW/FLI1 type 1 with potential use in cancer immunotherapy. EWS/FLI1 is a fusion protein frequently… »
A synthetic peptide derived from the protein ESW/FLI1 type 2 with potential use in cancer immunotherapy. EWS/FLI1 is a fusion protein frequently… »
Forming a single Ca2+-binding site in many calcium-binding proteins, the basic EF-Hand Domain consists of a conserved 12-residue loop region between two… »
Medicamento que se usa para planificar el tratamiento de cáncer por medio de la medición de las concentraciones de oxígeno en las… »
A monoclonal antibody used to treat psoriasis (a chronic skin disease). It is also being studied in the treatment of graft-versus-host disease… »
Anticuerpo monoclonal que se usa para tratar la psoriasis (una enfermedad crónica de la piel). Asimismo, está en estudio para el tratamiento… »
A substance being studied in the treatment of brain tumors and some other types of cancer. It increases the amount of oxygen… »
Sustancia en estudio para el tratamiento de tumores cerebrales y algunos otros tipos de cáncer. Aumenta la cantidad de oxígeno en los… »
The sodium salt form of efaproxiral, a propanoic acid and allosteric modifier of hemoglobin, with radiosensitizing activity. Efaproxiral binds non-covalently to the… »
An orally bioavailable thiazolidinedione and an agonist of peroxisome proliferator-activated receptor gamma (PPAR-gamma) with potential antineoplastic activity. Efatutazone binds to and activates… »
The dihydrochloride salt of efatutazone, an orally bioavailable compound and an agonist of peroxisome proliferator-activated receptor gamma (PPAR-gamma) with potential antineoplastic… »
A drug used with other drugs to treat infection with the human immunodeficiency virus (HIV). It blocks HIV from making copies of… »
Medicamento que se usa para tratar la infección por el virus de la inmunodeficiencia humana (VIH). Impide que el VIH haga copias… »
Problema médico inesperado que sucede durante el tratamiento con un medicamento u otra terapia. La causa de los efectos adversos no es… »
Problema que se presenta cuando un tratamiento afecta tejidos u órganos sanos. Algunos de los efectos secundarios comunes del tratamiento del cáncer… »
Problema que causa el tratamiento de una enfermedad, pero que habitualmente desaparece después de terminar el mismo. Los efectos secundarios de corto… »
Problema de salud que se presenta meses o años después que se diagnosticó una enfermedad o después que terminó el… »
Arbusto originario de China e India. Los tallos y las raíces se usan en la medicina tradicional como diurético y para el… »
This gene is involved in receptor binding. »
Human EFEMP1 wild-type allele is located in the vicinity of 2p16 and is approximately 58 kb in length. This allele, which encodes… »
An outward appearance. »
The date and time span for when the entity is active. »
Time for the amount of a radionuclide in a living organism to be reduced to half of its value at a given… »
A cell that performs a specific function in response to a stimulus; usually used to describe cells in the immune system. … »
A mature T-lymphocyte that has differentiated into a form that can mount an antigen-specific immune response. »
The deposition of hyaline material in the wall of the efferent arterioles. »
One of 12 to 14 small seminal ducts leading from the testis to the head of the epididymis. »
A neuron that sends impulses from the central nervous system to skeletal muscles, glands, and visceral organs. »
Nerve structures through which impulses are conducted from a nerve center toward a peripheral site. »
A granule composed of active and/or inert ingredient(s), and a mixture of acids and sodium bicarbonate, which release carbon dioxide when dissolved… »
A powder composed of active and/or inert ingredient(s), and a mixture of acids and sodium bicarbonate, which release carbon dioxide when dissolved… »
A tablet composed of active and/or inert ingredient(s), and a mixture of acids and sodium bicarbonate, which release carbon dioxide when dissolved… »
A drug used to treat depression and certain anxiety disorders. It may also be used to treat hot flashes in women who… »
Medicamento que se usa para tratar la depresión y ciertos trastornos de ansiedad. También se puede usar para tratar los sofocos de… »
Effectiveness. In medicine, the ability of an intervention (for example, a drug or surgery) to produce the desired beneficial effect. »
A study of the relative therapeutic efficacy of treatment of a disease. Usually this is a Phase II or III study. … »
For NDAs, ANDAs, and BLAs, this represents an application to modify the current indications or claims for a use for which the… »
An abnormal collection of fluid in hollow spaces or between tissues of the body. For example, a pleural effusion is a collection… »
En el campo de la medicina, la capacidad de una intervención (por ejemplo, la administración de un medicamento o una cirugía) de… »
A substance that is being studied in the prevention of cancer. It belongs to the family of drugs called antiprotozoals. »
The hydrochloride form of eflornithine, a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme required for… »
An ointment formulation of the hydrochloride salt of an ornithine decarboxylase (ODC) inhibitor with hair-growth inhibitory and potential chemopreventive activities. When administered… »
Sustancia en estudio para la prevención de cáncer. Es un tipo de antiprotozoario. »
A dodecylthio-phenylacetanilide derivative with hypocholesterolemic and anti-atherosclerotic properties. Eflucimibe is an inhibitor of acyl-Coenzyme A:cholesterol acyltransferase (ACAT), an intracellular enzyme which catalyzes… »
This gene is involved in cell-cell signaling. »
Human EFNB2 wild-type allele is located in the vicinity of 13q33 and is approximately 45 kb in length. This allele, which encodes… »