Medical Topics
A subdivision of adverse event data. »
A coded value specifying a subdivision within a larger category of an adverse event. »
A description of the adverse event and the treatment of the event. »
The toxicity grade value of the adverse event. »
A coded value specifying the representation of the criteria for determining whether an adverse event (experience or reaction) is considered unanticipated. … »
The verbatim description of the adverse event. »
An indication of whether an adverse event has occurred. »
Any noxious and unintended response(s) to a medical product or procedure, for which a causal relationship with this product or procedure is… »
Transmittal of Advertisements and Promotional Labeling for Drugs and Biologics for Human Use »
A drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It… »
The Committee advises and makes recommendations to the Director, NCI, for the oversight and integration of various planning and advisory groups serving… »
The process of defending or pleading the cause of another individual or group (from PSY94) »
A substance made from shark cartilage that is being studied for its ability to prevent the growth of new blood vessels that… »
A vaccine containing HER2/Neu-derived epitope (amino acids 776-790) linked to li-Key peptide (li-Key/HER2/neu hybrid peptide or AE37), and combined with granulocyte-macrophage colony-stimulating… »
A substance that is being studied in the treatment of cancer. It belongs to the families of drugs called protein tyrosine kinase… »
A substance being studied in the treatment of cancer. AEG35156 may kill cancer cells by blocking the production of a protein called… »
Physical activity that increases the heart rate and the body’s use of oxygen. It helps improve a person’s physical fitness. »
Any rod shaped bacteria with an oxygen based metabolism and has a cell wall that contains low levels of peptidoglycan and stains… »
Any spherical shaped bacteria with an oxygen based metabolism and a cell wall that contains low levels of peptidoglycan and stains pink… »
Any rod shaped bacteria with an oxygen based metabolism and has a peptidoglycan rich cell wall that stains dark purple with the… »
Any spherical shaped bacteria with an oxygen based metabolism and a peptidoglycan rich cell wall that stains dark purple with the Gram… »
A chemical process in which oxygen is used to make energy from carbohydrates (sugars). Also called aerobic respiration, cell respiration, and… »
A chemical process in which oxygen is used to make energy from carbohydrates (sugars). Also called aerobic metabolism, cell respiration, and… »
Any bacteria assigned to the genus Streptococcus that requires oxygen to grow or respirate. »
A taxonomic family of lactic acid bacterium in the phylum Firmicutes. »
A genus of aerobic, Gram positive, cocci shaped bacterium assigned to the phylum Firmicutes and the family Aerococcaceae. »
A species of Gram positive, cocci shaped bacteria assigned to the phylum Firmicutes. This bacteria is nonmotile, catalase negative, alpha hemolytic, urease… »
A species of facultatively anaerobic, Gram positive, cocci shaped bacteria assigned to the phylum Firmicutes. This bacteria is catalase negative, alpha hemolytic,… »
The combined organs and tissues of the respiratory tract and the upper part of the digestive tract (including the lips, mouth, tongue,… »
A taxonomic family of Gram negative, soil borne bacterium in the phylum Proteobacteria that includes the genera Aeromonas and Zobellella, among… »
A genus of Gram negative, rod shaped bacterium assigned to the phylum Proteobacteria and the family Aeromonadaceae. »
A species of aerobic or anaerobic, Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This bacteria is motile by polar… »
A species of facultatively anaerobic, Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This bacteria is oxidase positive, does not… »
A species of Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This bacteria is motile, oxidase and catalase positive, beta… »
A species of facultatively anaerobic, Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This bacteria is non motile, capable of… »
A species of Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This bacteria is oxidase positive, hemolytic, does not hydrolyze… »
A species of facultatively anaerobic, Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This bacteria is motile by polar flagella,… »
A species of Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This bacteria is hemolytic, produces acid from sucrose, produces… »
Other name for therapeutic hydrocortisone. »
Contents packaged under pressure that are released upon activation of an appropriate valve system. »
A foam that is packaged under pressure and released upon activation of an appropriate valve system. »
A mist that is packaged under pressure and released upon activation of an appropriate valve system. »
A container of medication intended to refill an aerosol dispenser. »
An aerosol inhalation formulation containing a yeast-derived glycosylated recombinant form of human granulocyte macrophage colony stimulating factor (GM-CSF) with potential immunostimulating… »
A homogenous solution comingled with a propellant and packaged under pressure. Upon activation of an appropriate valve system, the liquid is expelled… »
A spray that is packaged under pressure and released upon activation of an appropriate valve system. »
In medicine, to turn a liquid drug into a fine mist that can be inhaled. »
An aerosol formulation of aldesleukin, a recombinant form of interleukin-2 (IL-2), with potential immunostimulating activity. Upon IL-2 inhalation, this cytokine activates lymphokine-activated… »
An aerosolized liposomal preparation of rubitecan, a water-insoluble derivative of camptothecin with potential antineoplastic activity. Rubitecan (or 9-nitro-20 (S)-camptothecin) and its active… »
A suspension of solid or liquid particles in a gas, for example sulfate molecules (SO4-) found in the earth atmosphere. … »
The oil extracted from the seeds of Aesculus hippocastanum. Horse chestnut oil is used topically as a treatment for rheumatism and… »
Expressed in a variety of cell types by human MLLT4 Gene, 1816-aa 206-kDa AF-6 Protein is a possible signal transduction protein controlled… »
AF4/FMR2 family member 1 (1210 aa, ~131 kDa) is encoded by the human AFF1 gene. This protein may be involved in the… »
AF4/FMR2 family member 3 (1226 aa, ~133 kDa) is encoded by the human AFF3 gene. This protein is involved in the regulation… »
AF4/FMR2 family member 4 (1163 aa, ~127 kDa) is encoded by the human AFF4 gene. This protein plays a role in the… »
A synthetic peptide analogue of the naturally occurring alpha-melanocyte stimulating hormone (a-MSH) with potential photoprotective activity. Mimicking the action of a-MSH, afamelanotide… »
An orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic… »
A drug used to treat non-small cell lung cancer that has spread to other parts of the body. It is used in… »
This gene is involved in transcriptional regulation and translocations in the gene are associated with acute leukemia. »
Human AFF1 wild-type allele is located in the vicinity of 4q21 and is approximately 206 kb in length. This allele, which encodes… »
This gene is involved in transcriptional activation and is purported to play roles in lymphoid development and oncogenesis. »
Human AFF3 wild-type allele is located within 2q11.2-q12 and is approximately 595 kb in length. This allele, which encodes AF4/FRM2 family member… »
This gene plays a regulatory role in transcription and is involved in male germ cell differentiation. »
Human AFF4 wild-type allele is located in the vicinity of 5q31 and is approximately 88 kb in length. This allele, which encodes… »
The Affenpinscher is a small dog with a harsh, shaggy coat, and longer hair all over the face. The coat is usually… »
Nerve structures through which impulses are conducted from a peripheral part toward a nerve center. »
To be associated with; this is usually used as a description of the relationship of a person to an institution. »
A formal association between entities. »
In chemistry and biology, the strength of the attaction between two substances, such as two chemicals, or an antigen and an… »
A chromatographic separation technique based on the ability of proteins to bind specific ligands reversibly. »
In chemistry and biology, a compound that binds specific substances, such as proteins or nucleic acids. Many affinity reagents are antibodies. They… »
The Afghan Hound is a sight hound that is tall and slender with a long, narrow, refined head; and powerful jaws. The… »
A country in southern Asia, north and west of Pakistan, east of Iran. »
Denotes the inhabitants of Afghanistan, a person from there, or their descendants elsewhere. »
A blood coagulation disorder characterized by the complete absence of fibrinogen in the blood, resulting in bleeding. »
A tamoxifen metabolite with both estrogenic and anti-estrogenic effects. Afimoxifene has a higher affinity for the estrogen receptor than tamoxifen, and… »
A drug used with another drug to treat some postmenopausal women with advanced breast cancer that is hormone-receptor positive and HER2… »
A drug used with another drug to treat some postmenopausal women with advanced breast cancer that is hormone-receptor positive and HER2… »
A harmful substance made by certain types of mold (Aspergillus flavus and Aspergillus parasiticus) that is often found on poorly stored grains… »
A member of a group of mycotoxins produced by Aspergillus flavus and A. parasiticus. Alflatoxin B1 is the most hepatotoxic and hepatocarcinogenic… »
Aflatoxin B1 aldehyde reductase member 2 (359 aa, ~40 kDa) is encoded by the human AKR7A2 gene. This protein is involved in… »
A hepatocellular carcinoma that develops following exposure to aflatoxin. »
A protein normally produced by a fetus. AFP levels are usually undetectable in the blood of healthy adult men or women (who… »
A cancer vaccine composed of naked plasmid DNA of the gene for the tumor-associated antigen alpha-fetoprotein (AFP), a macromolecule that acts as… »
Human AFP wild-type allele is located within 4q11-q13 and is approximately 20 kb in length. This allele, which encodes alpha-fetoprotein, plays a… »
A substance being studied in the treatment of cancer. AFP464 kills cancer cells or stops them from dividing. It is a type… »
A question about whether an individual is or was afraid of having a seizure. »
The continent located south of Europe and bordered to the west by the South Atlantic and to the east by the India… »
Denotes a person with African ancestral origins who self identifies, or is identified, as African. The concept does not refer to those… »
A person having origins in any of the Black racial groups of Africa. Terms such as "Haitian" or "Negro" can be used… »
Every racial or ethnic group has specific health concerns. Differences in the health of groups can result from »
Denotes a person of African ancestral origins whose family settled in the Caribbean region. »
A medium-sized diurnal primate that is omnivorous, Chlorocebus sabaeus has a life span of 10 years in the wild and 25 years… »
A parasitic disorder caused by protozoa of the Trypanosoma brucei species. It is transmitted by flies and is endemic in various regions… »
To be done after eating breakfast. »
After breakfast and supper. »
After the ingestion of food. »
After meals and at bedtime. »
After supper or evening meal. »
After any operation, you'll have some side effects. There is usually some pain with surgery. There may also be swelling and soreness… »
An orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Afuresertib binds to and inhibits… »
A quinazoline derivative that selectively inhibits EGFR kinase activity and suppresses the growth of psoriatic keratinocytes. »
A tyrphostin compound inhibiting receptor autophosphorylation by inhibiting protein tyrosine kinase and is used to study receptor function. »
A substance that is being studied in the treatment of cancer. It belongs to the families of drugs called angiogenesis inhibitors and… »
A cyclin-dependent kinase (CDK) inhibitor with antineoplastic activity. AG-024322 selectively inhibits cyclin-dependent kinases (particularly CDK1,2 and 4), enzymes that regulate cell cycle… »
A substance being studied in the treatment of breast cancers caused by mutations (changes) in the BRCA1 and BRCA2 genes. It is… »
A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called glycinamide ribonucleotide formyl… »
A substance that is being studied in the treatment of cancer. It is a matrix metalloproteinase inhibitor and belongs to the family… »
A substance that is being studied in the treatment of liver cancer. It belongs to the family of drugs called thymidylate synthase… »
A condition in which certain nerve cells are missing from the muscle layers of part of the large intestine. This causes severe… »
A method to determine microbial susceptibility to antibiotics in which test bacteria is inoculated onto agar plates with serial dilutions of know… »
A dietary supplement containing an extract of the Basidiomycete fungus Agaricus blazei Murill with potential chemopreventive, antineoplastic and immunopotentiating activities. Agaricus blazei… »
An electrophoresis gel composed of agarose dissolved in an aqueous buffer. »
A type of electrophoresis that uses a matrix of highly purified agar to separate large molecules. »
The essential oil from leaves of Agathosma betulina. Agathosma betulina leaf oil is used as a flavoring and in medicinal preparations. … »
The tricosasodium salt of a synthetic 24-mer oligonucleotide containing 3 CpG motifs with potential antineoplastic and immunostimulatory activity. Agatolimod selectively targets Toll-like… »
A finding of abnormal cells in a Pap test. The glandular cells come from the inner part of the cervix or the… »
Diagnostic tests designed to be performed at specific age markers. »
The age at which a woman gave birth to her first live child. »
Age of first menstruation. A risk factor for breast cancer »
The age at which permanent cessation of menses occurs. »
The age of the subject at the time of the vaccination. »
The age of a person at the start of a specific event. »
The rate of disease occurrence, or proportion of disease occurrences in a given population, during a specified time period, statistically modified to… »
The death rate, or proportion of a given population that dies, during a specified time period, statistically modified to eliminate the effect… »
Prostate-specific antigen (PSA) level defined according to specific age groups or ranges, which takes into account the natural increase of PSA levels… »
The length of a person's life, stated in months since birth. »
Atrophy of the nervous system tissues and/or muscle tissues that is related to aging. »
A condition in which there is a slow breakdown of cells in the center of the retina (the light-sensitive layers of nerve… »
The Agency for Healthcare Research and Quality (AHRQ), a component of the US Department of Health and Human Services, Public Health Service,… »
An active power or cause (as principle, substance, physical or biological factor, etc.) that produces a specific effect. »
The act of the dispensing, applying, or tendering a medical product or other agent. »
An agent that exerts an effect on the synthesis or function of blood, blood components or body fluids. »
An agent that exerts a physiologic effect on any anatomic entity that is part of the cardiovascular system, including the heart and… »
An agent that exerts an effect on metabolism or any anatomic entity that is part of the gastrointestinal tract. »
An agent that exerts a physiologic effect on any anatomic entity that is part of the integumentary system, including skin, nails and… »
Any agent that exerts an effect on muscle, bones and joints. »
An agent that exerts a physiologic effect on neurotransmission or on any anatomic entity that is part of the nervous system, including… »
An agent that exerts a physiologic effect on the organs of special senses, including the eyes, ears and nose. This category includes… »
An agent that exerts a physiologic effect on any anatomic entity that is part of the respiratory tract and airways. »
An attribute used to characterize a change in the agent dose regimen in the context of its relation to the original documented… »
A scientist or other professional who is an independent, non-participant in the agent development effort. The person is responsible for contributing expert… »
Administration of an agent within 30 days of a specified date. »
An authorized person who is appointed to audit and officially inspect the warehousing, prescribing, dispensing, distribution, administration and documentation practices related to… »
Code name for a synthetic defoliant developed for military use. Agent Orange is a mixture of two chemicals, 2,4, dichlorophenoxyacetic acid… »
In cancer prevention, a clinical trial that studies whether taking certain medicines, vitamins, minerals, or food supplements can prevent cancer. Also called… »
Infectious agents, which while normally present but remaining benign under the control of the immune system, become virulent and pathogenic in immune-compromised… »
Human AGER wild-type allele is located in the vicinity of 6p21.3 and is approximately 3 kb in length. This allele, which encodes… »
A substance that makes particles (such as bacteria or cells) stick together to form a clump or a mass. »
A flare of acne which may be precipitated by variety of factors, including hormonal activity, stress, oils and oily cosmetics, sweat, overwashing,… »
A chronic, inflammatory skin condition characterized by raised, ring shaped eruptions occurring singly or in groups; often on the tops of the… »
A condition causing exacerbation of the clinical features of neurofibromatosis. »
Something that makes a condition worse. For example, tobacco smoke is an aggravating factor for asthma. »
The determination of the amount of aggrecan chondroitin sulfate epitope 846 present in a sample. »
A genus of facultatively anaerobic, Gram negative, coccobacilli shaped bacterium assigned to the phylum Proteobacteria and the family Pasteurellaceae. »
A species of facultatively anaerobic, Gram negative, coccobacilli shaped bacteria assigned to the phylum Proteobacteria. This bacteria is non motile, catalase and… »
A species of facultatively anaerobic, Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This bacteria is catalase and urease negative,… »
A species of facultatively anaerobic, Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This bacteria is catalase positive, oxidase negative,… »
A process by which particles collect to form a cohesive mass or cluster. The resulting structure is called an aggregate. »
In medicine, describes a tumor or disease that forms, grows, or spreads quickly. It may also describe treatment that is more severe… »
An aggressive non-Hodgkin lymphoma occurring in adults. Representative examples include Burkitt lymphoma, precursor B-lymphoblastic lymphoma, precursor T-lymphoblastic lymphoma, and adult T-cell… »
A type of soft tissue tumor that forms in fibrous (connective) tissue, usually in the arms, legs, or abdomen. It may also… »
A type of lymphoma that grows and spreads quickly and has severe symptoms. Also called high-grade lymphoma and intermediate-grade lymphoma. »
A rare, highly aggressive, Epstein-Barr virus-associated leukemia, also known as aggressive NK-cell leukemia/lymphoma; it may represent the leukemic counterpart of nasal type… »
A non-Hodgkin lymphoma with an aggressive clinical course. Representative examples include Burkitt lymphoma, mantle cell lymphoma, and angioimmunoblastic T-cell lymphoma. … »
An osteoblastoma characterized by the presence of prominent epithelioid osteoblasts and recurrences. »
An aggressive and progressive mast cell neoplasm characterized by systemic infiltration of internal organs by aggregates of neoplastic mast cells. There is… »
The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time. … »
The study of how nutritional needs change with aging. »
Any physiological aspect of aging; irreversible changes in an organism that occur over time and lead to a more mature condition. … »
A condition in which a person is unable to relax and be still. The person may be very tense and irritable, and… »
An adenoviral vector engineered to express the herpes simplex virus thymidine kinase (HSV-tk) gene, which, when administered in conjunction with a synthetic… »
A progressive, chronic disease in which the bone marrow is replaced by fibrous tissue and blood is made in organs such as… »
A rare disorder characterized by the lack of ability to recognize individuals, objects, shapes, sounds, or smells. There is no loss of… »
A drug or substance that binds to a receptor inside a cell or on its surface and causes the same action as… »
A human immunoglobulin (Ig) G1 monoclonal antibody directed against the cell surface receptor CD40 with potential immunostimulatory and antineoplastic activities. Upon intratumoral… »
A sensation of great anguish and suffering. »
An intense fear of being in open places or in situations where it may be hard to escape, or where help may… »
An anxiety disorder characterized by agoraphobia in the absence of a history of panic attacks; the individual fears incapacitation or humiliation in… »
This gene is involved in differentiation. It also plays a putative role in tumor metastasis. »
Human AGR2 wild-type allele is located in the vicinity of 7p21.3 and is approximately 13 kb in length. This allele, which encodes… »
A type of white blood cell. Monocytes and lymphocytes are agranulocytes. »
A marked decrease in the number of mature granulocytes (most often neutrophils) in the peripheral blood. »
The act of agreeing to a plan, protocol, or arrangement. Also used to describe a harmony of opinion. »
The science of soil cultivation, crop production, and livestock raising. »
The heparan sulphate proteoglycan agrin is well known as the key assembly factor of postsynaptic differentiation at the neuromuscular junction (NMJ), but… »
Small motile rod bacteria that can reduce nitrates and cause galls on plant stems. »
A species of Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This bacteria is motile, non sporeforming, oxidase and catalase… »
A species of Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This bacteria is motile by flagella and mediates the… »
This gene plays a critical role in blood pressure maintenance and in the pathogenesis of essential hypertension and preeclampsia. »
Human AGT wild-type allele is located within 1q42-q43 and is approximately 12 kb in length. This allele, which encodes angiotensinogen protein, plays… »
This gene plays a role in the regulation of the central nervous system and cardiovascular functions that are mediated by angiotensin. … »
Human AGTR2 wild-type allele is located within Xq22-q23 and is approximately 4 kb in length. This allele, which encodes type-2 angiotensin II… »
This gene plays a role in angiotensin signaling. »
Human AGTRAP wild-type allele is located in the vicinity of 1p36.22 and is approximately 19 kb in length. This allele, which encodes… »
A state in central Mexico. Its capital is Aguascalientes. »
A term that has been used to describe abnormal cells that come from glands in the walls of the cervix (the lower,… »
AH receptor-interacting protein (330 aa, ~37 kDa) is encoded by the human AIP gene. This protein is involved in the modulation of… »
One of a group of substances that are found in several types of fruit and in milk. They are used in skin… »
Human AHCY wild-type allele is located in the vicinity of 20q11.22 and is approximately 32 kb in length. This allele, which encodes… »
The Ah receptor, bHLH/PAS transcription factor, upon binding of an agonist such as 2,3,7,8-tetrachlorodibenzo-p-dioxin translocates into the nucleus and heterodimerizes with the… »
Human AHR wild-type allele is located in the vicinity of 7p15 and is approximately 48 kb in length. This allele, which encodes… »
A regimen consisting of doxorubicin and ifosfamide used for the treatment of unresectable soft tissue sarcoma. »
A sporadic genetic syndrome characterized by agenesis of the corpus callosum, infantile spasms, and chorioretinal lacunae. It is associated with the… »
This gene plays a role in both class-switch recombination in B-lymphocytes and cytidine deamination. »
Human AICDA wild-type allele is located in the vicinity of 12p13 and is approximately 11 kb in length. This allele, which encodes… »
A regimen consisting of tretinoin (all-trans retinoic acid or ATRA) and idarubicin used as an induction treatment for adult acute promyelocytic leukemia… »
A disease caused by the human immunodeficiency virus (HIV). People with AIDS are at an increased risk for developing certain cancers and… »
The ACSB provides qualified researchers with tissue, cell, blood and fluid specimens, as well as clinical data from patients with HIV-related… »
A clinical trial designed to evaluate the development, safety, and efficacy of vaccines and therapeutics directed against AIDS. »
Study of the occurrence, distribution, and containment of the acquired immunodeficiency syndrome (AIDS). Used for the scientific discipline as a whole… »
AIDS related research with a minimum of 20% (or $100,000) relevance to individuals with hemophilia, a sex-linked hereditary blood defect that occurs… »
Established in 1995 to carry out Phase I and II studies of innovative therapies for AIDS malignancies. »
Subgroups of AIDS patients. »
A morphologic variant of diffuse large B-cell lymphoma occurring in HIV-positive patients. »
AIDS related research with a minimum of 20% research efforts related to females 12 years of age or older. To include: Pregnant… »
Any studies (usually immunologic or virologic) that, although not directly concerned with AIDS, could reasonably be expected to contribute information useful in… »
A carcinoma arising from the anus and occurring in HIV-positive patients. Homosexual HIV-positive men have an increased risk of developing anal squamous… »
A non-Hodgkin lymphoma arising from the anus and occurring in HIV-positive patients. Homosexual HIV-positive men have an increased risk of developing… »
A Burkitt lymphoma occurring in HIV-positive patients. »
Types of cancer that are more likely to occur in people who are infected with the human immunodeficiency virus (HIV). The most… »
A carcinoma that arises from the cervix in a patient with acquired immunodeficiency syndrome. »
A Kaposi sarcoma arising from the cervix in patients who are infected with the human immunodeficiency virus. »
A diffuse large cell lymphoma developing in an HIV positive patient. »
A non-Hodgkin lymphoma occurring in HIV-positive patients. It is composed of a mixture of lymphocytes of various sizes. »
A non-Hodgkin lymphoma occurring in HIV-positive patients. It is composed of small cleaved lymphocytes. »
A non-neoplastic or neoplastic disorder arising as a result of the immunologic defects caused by Autoimmune Deficiency Syndrome. »
A Kaposi sarcoma arising from the stomach in patients who are infected with the human immunodeficiency virus. »
An opportunistic infection caused by herpes zoster in a patient with AIDS. »
Hodgkin lymphoma secondary to AIDS. An increased incidence of Hodgkin lymphomas has been observed in HIV positive patients. Most cases are morphologically… »
An opportunistic infection caused by the human papillomavirus in a patient with AIDS. »
The most aggressive form of Kaposi sarcoma. It presents in patients who are infected with the human immunodeficiency virus. It can affect… »
A lymphoblastic lymphoma occurring in HIV-positive patients. »
An aggressive lymphoma that develops in HIV-positive patients. There is a significant increase in the incidence of lymphomas associated with the… »
Function: Provide a national scientific forum to identify research opportunities and to provide recommendations on research priorities, resource needs, and how best… »
A malignant neoplasm arising from the anus and occurring in HIV-positive patients. Representative examples include squamous cell carcinoma and non-Hodgkin… »
A malignant neoplasm that arises from the cervix in a patient with acquired immunodeficiency syndrome. This category includes cervical carcinoma, Kaposi sarcoma,… »
Malignant neoplasms that develop in HIV infected patients. The most common AIDS-related malignant neoplasms are Kaposi sarcoma, non-Hodgkin lymphoma, anal carcinoma,… »
A non-Hodgkin lymphoma that develops in a patient with AIDS. »
A non-Hodgkin lymphoma that arises from the cervix in a patient with acquired immunodeficiency syndrome. »
Pelvic inflammatory disease that develops in a patient with HIV/AIDS. »
A lymphoma (non-Hodgkin or Hodgkin) arising from the central nervous system and occurring in HIV-positive patients. »
AIDS related research with a minimum of 20% (or $100,000) relevance to individuals of African descent »
AIDS clinical trials related to children 0-18 years of age. These trials include pregnant females, neonates, and infants. »
AIDS clinical trials related to individuals of non-Caucasian descent. »
Clinical trials related to the development of vaccines and therapeutics directed against AIDS-related malignancies. These trials include the following malignancies: Kaposi's sarcoma,… »
Clinical trials related to the development of vaccines and therapeutics directed against opportunistic infections associated with HIV infection. These trials include the… »
AIDS clinical trials related to females 12 years of age or older. These trials include pregnant women, women at risk of AIDS,… »
AIDS related research with a minimum of 20% (or $100,000) relevance to individuals of Mexican, Cuban, Puerto Rican, Central American, or South… »
AIDS related research with a minimum of 20% (or $100,000) relevance to individuals of homosexual orientation »
AIDS related research with a minimum of 20% (or $100,000) research efforts related to foreign countries. To include: Awards to scientists… »
AIDS related research with a minimum of 20% (or $100,000) research efforts related to individuals of non-Caucasian descent, and individuals of Hispanic… »
AIDS related research with a minimum of 20% (or $100,000) relevance to individuals who are Asian/Pacific Islanders or Native Americans, including American… »
AIDS related research with a minimum of 20% (or $100,000) research efforts related to females 12 years of age or older. To… »
A regimen consisting of cytarabine (Ara-C), idarubicin and etoposide, used as an induction treatment for pediatric acute myeloid leukemia (AML). »
Programmed cell death is induced by many different factors and involves numerous signaling pathways, some dependent on caspase proteases and others that… »
A regimen consisting of doxorubicin, ifosfamide and methotrexate used for the treatment of unresectable soft tissue sarcoma. »
Human AIM1 wild-type allele is located in the vicinity of 5p13.3 and is approximately 40 kb in length. This allele, which encodes… »
Human AIM2 is located in the vicinity of 1q22 and is approximately 40 kb in length. This gene, which encodes membrane-associated transporter… »
A cancer vaccine containing the three frame shift peptides (FSP) AIM2(-1), HT001(-1) and TAF1B(-1), with potential immunomodulating activity. Upon administration, the AIM2(-1)/HT001(-1)/TAF1B(-1)… »
This gene plays a role in the regulation of both ubiquitination and translation. »
Human AIMP2 wild-type allele is located in the vicinity of 7p22 and is approximately 15 kb in length. This allele, which encodes… »
Abnormal Involuntary Movement Scale (AIMS) Dental Status, Current problems with teeth and/or dentures. »
Abnormal Involuntary Movement Scale (AIMS) Global Judgments, Incapacitation due to abnormal movements. »
Abnormal Involuntary Movement Scale (AIMS) Facial and Oral Movements, Jaw, e.g., biting, clenching, chewing, mouth opening, lateral movement. »
Abnormal Involuntary Movement Scale (AIMS) Facial and Oral Movements, Lips and perioral area, e.g., puckering, pouting, smacking. »
Abnormal Involuntary Movement Scale (AIMS) Extremity Movements, Lower (legs, knees, ankles, toes), e.g., lateral knee movement, foot tapping, heel dropping, foot squirming,… »
Abnormal Involuntary Movement Scale (AIMS) Facial and Oral Movements, Muscles of facial expression, e.g., movements of forehead, eyebrows, periorbital area, cheeks. Include… »
Abnormal Involuntary Movement Scale (AIMS) Trunk Movements, Neck, shoulders, hips, e.g., rocking, twisting, squirming, pelvic gyrations. Include diaphragmatic movements. »
Abnormal Involuntary Movement Scale (AIMS) Dental Status, Does patient usually wear dentures? »
Abnormal Involuntary Movement Scale (AIMS) Global Judgments, Patient's awareness of abnormal movements. »
Abnormal Involuntary Movement Scale (AIMS) Global Judgments, Severity of abnormal movements, based on the highest single score on the above items. … »
Abnormal Involuntary Movement Scale (AIMS) Facial and Oral Movements, Tongue. Rate only increase in movement both in and out of mouth, not… »
Abnormal Involuntary Movement Scale (AIMS) Extremity Movements, Upper (arms, wrists, hands, fingers). Include movements that are choreic (rapid, objectively purposeless, irregular, spontaneous)… »
A question associated with the AIMS questionnaire. »
Spontaneous autoamputation of a digit, usually the fifth toe. It results from the formation of a fibrotic band which constricts the full… »
Human AIP wild-type allele is located in the vicinity of 11q13.3 and is approximately 8 kb in length. This allele, which encodes… »
A mixture of gases making up the earth's atmosphere, consisting mainly of nitrogen, oxygen, argon, and carbon dioxide. »
Separation of dry particles into size-differentiated fraction by conveying the particles in a stream of gas. »
A filtering device designed to remove particles from air. »
A device designed to remove air from a space or fluid. »
The presence of bubbles of gas in the vascular system; occurrence is related to the entry of air into the venous circulation… »
Air pollution is a mixture of solid particles and gases in the air. Car emissions, chemicals from factories, dust, pollen and mold… »
A composite part of an air pump or a larger device that includes an air pump. »
Drying by exposure to forced air. »
Airborne Particulate Matter is a broad class of materials and substances of minute size present in the air that originate from industrial… »
An accident taking place aboard, or involving, any type of aircraft. »
The Airedale Terrier is a large terrier with a harsh wiry coat, long flat head, and a deep chest. The coat should… »
Number of respiratory epithelial cells is increased diffusely or focally. Frequently luminal protrusions are observed, sometimes forming papillae. Mucous (goblet)… »
A rare infantile hemangioma in the airway, usually in the subglottic area or trachea. It may or may not be associated with… »
A standardized rating scale developed by Barley et al in 1988 to measure health status and detect changes in quality of life… »
A condition in which abnormal cells are found in the glandular tissue that lines certain internal organs, such as the uterus, cervix,… »
A system to describe the amount and spread of cancer in a patient’s body, using TNM. T describes the size of the… »
A cancer stage defined according to the AJCC 6th edition criteria. »
A cancer stage defined according to the AJCC 7th edition criteria. »
A species of soil-borne, dimorphic fungus that is the causative agent of Histoplasmosis. »
A proprietary topical formulation. Upon subcutaneous administration, the active ingredient in AK 3012 may inhibit actinic keratosis. »
This gene plays a role in the regulation of protein kinase A activity. »
Human AKAP10 wild-type allele is located in the vicinity of 17p11.1 and is approximately 73 kb in length. This allele, which encodes… »
This gene plays a role in signal transduction and angiogenesis. »
Human AKAP12 wild-type allele is located within 6q24-q25 and is approximately 116 kb in length. This allele, which encodes A-kinase anchor protein… »
This gene is involved in signal transduction and protein trafficking. »
Human AKAP13 wild-type allele is located within 15q24-q25 and is approximately 515 kb in length. This allele, which encodes A-kinase anchor protein… »
Chromatin packaging of the genome is dynamic, changing with the cell cycle and with transcriptional regulation. During mitosis, chromatin is condensed… »
This gene plays a role in signal transduction and modulates synaptic transmission. »
Human AKAP9 wild-type allele is located within 7q21-q22 and is approximately 170 kb in length. This allele, which encodes A-kinase anchor protein… »
A fusion gene (~4.6 kb) that results from a paracentric chromosomal inversion inv(7)(q21-22q34) which fuses exon 8 of the AKAP9 gene to… »
A fusion protein (1492 aa, ~172 kDa) encoded by the AKAP9/BRAF fusion gene. This protein is comprised of part of the A-kinase… »
An uncomfortable feeling of inner restlessness and inability to stay still; this is a side effect of some psychotropic drugs. »
The Akita is a powerful, solid, well-proportioned and distinctive looking dog. This breed is strong and muscular with a flat, heavy head… »
Originally disseminated by Detweiler and carried by Furth (1928-1936) and the Rockefeller Institute for subsequent generations. The AKR mouse has an albino… »
This gene plays a role in the reduction of biogenic and xenobiotic aldehydes. »
Human AKR1A1 wild-type allele is located within 1p33-p32 and is approximately 20 kb in length. This allele, which encodes alcohol dehydrogenase [NADP(+)]… »
This gene is involved in the metabolism of aldehydes and ketones. »
Human AKR1C1 wild-type allele is located within 10p15-p14 and is approximately 91 kb in length. This allele, which encodes aldo-keto reductase family… »
This gene plays a role in the metabolism of steroid hormones. »
Human AKR1C2 wild-type allele is located within 10p15-p14 and is approximately 30 kb in length. This allele, which encodes aldo-keto reductase family… »
This gene is involved in the detoxification of xenobiotics. »
Human AKR7A2 wild-type allele is located within 1p35.1-p36.23 and is approximately 8 kb in length. This allele, which encodes aflatoxin B1 aldehyde… »
A group of enzymes involved in several processes related to cell growth and survival. Akt enzymes help to transfer signals inside… »
An orally bioavailable inhibitor of the serine/threonine protein kinase AKT (protein kinase B) isoforms 1 and 2 (AKT1/2) with potential antineoplastic… »
A molecular genetic abnormality indicating the presence of mutations in the AKT family of genes. This family includes the AKT1, AKT2,… »
An orally bioavailable inhibitor of the serine/threonine protein kinase AKT (protein kinase B) with potential antineoplastic activity. AKT inhibitor ARQ 092 binds… »
A novel pyrrolopyrimidine derivative, and an orally available inhibitor of the serine/threonine protein kinase AKT (protein kinase B) with potential antineoplastic… »
An orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GDC-0068 binds to… »
An orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GSK2141795 binds to… »
An orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor LY2780301 binds to… »
An orally bioavailable allosteric inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor MK2206 binds… »
An orally bioavailable indole-3-carbinol (I3C) analogue inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic and antiangiogenic… »
Many cell-surface receptors induce production of second messengers like PIP3, phosphatidylinositol 3,4,5-trisphosphate, that convey signals to the cytoplasm from the cell… »
This gene is involved in signal transduction and negative regulation of apoptosis. It also plays a role in glucose transport, glycogen synthesis,… »
A change in the nucleotide sequence of the AKT1 gene. »
A variation in the amino acid sequence for the RAC-alpha serine/threonine-protein kinase protein. »
Human AKT1 wild-type allele is located in the vicinity of 14q32.32 and is approximately 26 kb in length. This allele, which encodes… »
This gene plays a role in the regulation of mTOR signaling. »
Human AKT1S1 wild-type allele is located in the vicinity of 19q13.33 and is approximately 9 kb in length. This allele, which encodes… »
Human AKT2 wild-type allele is located within 19q13.1-q13.2 and is approximately 53 kb in length. This allele, which encodes RAC-beta serine/threonine-protein kinase… »
Human AKT3 wild-type allele is located within 1q43-q44 and is approximately 355 kb in length. This allele, which encodes RAC-gamma serine/threonine-protein kinase… »
A combination of two drugs used to prevent nausea and vomiting caused by chemotherapy. It is a combination of netupitant and palonosetron… »
A mixture of neutral lipids (70%), phosphatidylcholine (20%) and phosphatidylethanolamine (10%) extracted from egg yolk. AL721 removes cholesterol from outer cell membranes,… »
A long-acting, sulfhydryl-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, alacepril is rapidly metabolized to captopril; captopril competitively binds… »
A rare disorder in which there are defects in the small tubes that carry bile (fluid that helps digest fat) out of… »
A purine nucleotide analog prodrug with activity against wild-type and lamivudine-resistant hepatitis B virus (HBV). Alamifovir acts by inhibiting viral DNA priming… »
An archipelago in the Baltic Sea at the entrance to the Gulf of Bothnia between Sweden and Finland. »
A small non-essential amino acid in humans, Alanine is one of the most widely used for protein construction and is involved in… »
An enzyme that is normally found in healthy kidneys. It may be found at high levels in the urine when there are… »
The determination of the amount of alanine aminopeptidase present in a sample. »
Alanine aminotransferase 1 (496 aa, ~55 kDa) is encoded by the human GPT gene. This protein plays a role in both amino… »
Alanine aminotransferase 2 (523 aa, ~58 kDa) is encoded by the human GPT2 gene. This protein is involved in both pyruvate biosynthesis… »
An increase in the level of alanine aminotransferase in the blood. »
A quantitative measurement of alanine aminotransferase present in a sample. »
The determination of the ratio of alanine aminotransferase (ALT) compared to aspartate aminotransferase (AST) present in a sample. The measurement may be… »
An enzyme found in the liver and other tissues. A high level of alanine transferase released into the blood may be a… »
A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called antimetabolites. Also called… »
A composite part of an alarm or a larger device that includes an alarm. »
A device designed to signal the occurrence of a particular event. »
Instructional activity designed to teach patients how to vocalize with a non-functioning or absent larynx. »
This gene plays a role in both lipid metabolism and heme biosynthesis. »
Human ALAS1 wild-type allele is located in the vicinity of 3p21.1 and is approximately 16 kb in length. This allele, which encodes… »
Denotes a person having origins in any indigenous people of Alaska and their descendants and who maintains tribal affiliation, or community or… »
The Alaskan Malamute is a large, strong dog with a thick, coarse double coat and a plumed tail held over the… »
The percentage of solar radiation that is reflected relative to the total incoming radiation. »
A broad-spectrum, synthetic benzimidazole-derivative anthelmintic. Albendazole interferes with the reproduction and survival of helminths by inhibiting the formation of microtubules from… »
The goal of the Albert Einstein Cancer Center is to foster basic, clinical, population- based, and translational research in an effort to… »
A long-acting glucagon-like peptide-1 (GLP-1) receptor agonist, with antihyperglycemic activity. Albiglutide is composed of a GLP-1 (7-36) dimer fused to recombinant human… »
A group of genetic conditions marked by little or none of the pigment melanin in the skin, hair, and/or eyes. People with… »
A long-acting, recombinant fusion polypeptide consisting of interferon alpha-2b (IFNa-2b) linked to human albumin (alb-IFN), with antiviral and immunomodulatory activity. Albinterferon alpha-2b… »
A quantitative measurement of albumin present in a sample. »
The determination of the ratio of albumin compared to creatinine protein present in a urine sample. The measurement may be expressed as… »
The determination of the ratio of albumin compared to globulin in a blood sample. The measurement may be expressed as a ratio… »
The determination of the ratio of the albumin compared with total protein in a biological sample. The measurement may be expressed as… »
A racemic mixture of the r-isomer levalbuterol and s-albuterol, a short-acting sympathomimetic agent with bronchodilator activity. Albuterol stimulates beta-2 adrenergic receptors in… »
The sulfate salt of the short-acting sympathomimetic agent albuterol, a 1:1 racemic mixture of (R)-albuterol and (S)-albuterol with bronchodilator activity. Albuterol stimulates… »
A taxonomic family of bacterium in the phylum Proteobacteria that includes the genera Bordetella, Oligella and Sutterella. »
A genus of Gram-negative, aerobic, rod-shaped bacteria in the family Alcaligenaceae. »
A species of obligately aerobic, Gram negative, rod shaped bacteria assigned to the phylum Proteobacteria. This bacteria is motile, oxidase positive, catalase… »
This gene plays a role in cellular adhesion events involving immune cells, such as monocytes and leukocytes. »
Human ALCAM wild-type allele is located in the vicinity of 3q13.1 and is approximately 210 kb in length. This allele, which encodes… »
A form of the natural substance carnitine that is being studied as a way to prevent tissue damage caused by chemotherapy. Carnitine… »
A microscopy staining method that utilizes periodic acid, an oxoacid of iodine, Schiff reagent, the reaction product of fuchsine and sodium bisulfite,… »
A microscopy staining method that utilizes alcian blue, a cationic, water soluble copper-containing phthalocyanine dye to determine the presence of acid mucopolysaccharides… »
An aggressive (fast-growing) type of non-Hodgkin lymphoma that is usually of the T-cell type. The cancer cells express a marker called CD30… »
The dipropionate salt form of alclometasone, a synthetic corticosteroid with low to medium potency. Alclometasone dipropionate is a glucocorticoid receptor agonist that… »
Alcohol dehydrogenase 1C (375 aa, ~40 kDa) is encoded by the human ADH1C gene. This protein is involved in the oxidation of… »
A chemical substance found in drinks such as beer, wine, and liquor. It is also found in some medicines, mouthwashes, household products,… »
A class of compounds where a hydroxyl (OH) group is attached to single bonded hydrocarbons. Alcohols are classified according to the… »
An injection of ethanol (alcohol) through the skin directly into a tumor to kill cancer cells. Ultrasound or a CT scan is… »
The use of alcoholic beverages to excess, either on individual occasions ("binge drinking") or as a regular practice. »
Consumption of liquids containing ethanol, including the behaviors associated with drinking the alcohol. »
Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation… »
Alcohol dehydrogenase [NADP(+)] (325 aa, ~37 kDa) is encoded by the human AKR1A1 gene. This protein plays a role in the reduction… »
Alcohol dehydrogenase 4 (380 aa, ~40 kDa) is encoded by the human ADH4 gene. This protein plays a role in alcohol… »
A chronic disease in which a person craves drinks that contain alcohol and is unable to control his or her drinking. … »
Increased sensitivity to the adverse effects of alcohol, which can include nasal congestion, skin flushes, heart dysrhythmias, nausea, vomiting, indigestion and… »
A physical or cognitive mental abnormality caused by maternal alcohol consumption and its toxic effect on the developing embryo during pregnancy. … »
A cognitive and neurological disorder due to fetal intrauterine exposure to maternal alcohol consumption. Typically, this presents without facies or other growth… »
A description of an individual's current and past experience with alcoholic beverage consumption. »
A syndrome which occurs in individuals with a history of alcohol abuse. It is caused by prolonged alcohol-induced neurological damage and malnutrition… »
An esophageal carcinoma that results from alcohol consumption. The alcohol-related esophageal carcinomas are always of squamous cell type. There is… »
A hepatocellular carcinoma that develops following alcohol-induced injury of the liver parenchyma. »
A carcinoma that arises from the larynx and is caused by alcohol abuse. »
A drink, including beer, wine or liquor, that is made by fermentation of raw materials. An alcoholic beverage contains ethanol (alcohol) as… »
Atrophy of the cerebral cortex and/or cerebellum due to chronic ethanol consumption. »
A dilated cardiomyopathy which is associated with consumption of large amounts of alcohol over a period of years. »
A disorder of the liver characterized by the presence of fibrotic scar tissue instead of healthy liver tissue. This condition is attributed… »
A disorder caused by damage to the liver parenchyma due to alcohol consumption. It may present with an acute onset or follow… »
A chronic disease in which a person craves drinks that contain alcohol and is unable to control his or her drinking. … »
A drug used to treat early basal cell skin cancer and certain other skin conditions. It is being studied in the treatment… »
A type of chemical substance made from alcohol. Aldehydes are found in essential oils (scented liquid taken from plants). »
Aldehyde dehydrogenase X, mitochondrial (517 aa, ~57 kDa) is encoded by the human ALDH1B1 gene. This protein is involved in the metabolism… »
Aldehyde dehydrogenase mitochondrial protein (517 aa, ~56 kDa) is encoded by the human ALDH2 gene. This protein is involved in intermediary… »
A drug used to treat some types of cancer. It is a form of interleukin-2, a cytokine made by leukocytes (white blood… »
This gene plays a role in biosynthesis, cell differentiation and intercellular communication. »
Human ALDH1A2 wild-type allele is located in the vicinity of 15q22.1 and is approximately 113 kb in length. This allele, which encodes… »
This gene is involved in the mediation of alcohol detoxification. »
Human ALDH1B1 wild-type allele is located in the vicinity of 9p11.1 and is approximately 6 kb in length. This allele, which encodes… »
This gene plays a role in intermediary metabolism. »
Human ALDH2 wt allele is located in the vicinity of 12q24.2 and is approximately 43 kb in length. This allele, which encodes… »
Aldo-keto reductase family 1 member C1 (323 aa, ~37 kDa) is encoded by the human AKR1C1 gene. This protein is involved in… »
Aldo-keto reductase family 1 member C2 (323 aa, ~37 kDa) is encoded by the human AKR1C2 gene. This protein plays a role… »
The determination of the amount of aldolase present in a sample. »
Any substance that inhibits aldehyde reductase (aldose reductase), an enzyme that participates in glucose metabolism and osmoregulation. Aldehyde reductase has been implicated… »
A steroid hormone made by the adrenal cortex (the outer layer of the adrenal gland). It helps control the balance of water… »
The determination of the amount of aldosterone hormone present in a sample. »
A class of agents that act by selectively inhibiting aldosterone receptor activation with diuretic activity. Aldosterone receptor antagonists bind to and block… »
An adenoma of the adrenal cortex that produces aldosterone. It may be associated with Conn syndrome. Clinical presentation includes hypertension,… »
Sodium transport across the tight epithelia of Na+ reabsorbing tissues such as the distal part of the kidney nephron and colon is… »
A 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH) with antineoplastic activity. Following intravenous administration, aldoxorubicin binds selectively to the… »
An inherited immune disorder that occurs in young boys. It causes eczema (a type of skin inflammation), a decrease in the number… »
A drug used to treat non-small cell lung cancer that has spread to other parts of the body and has a mutated… »
A drug used to treat non-small cell lung cancer that has spread to other parts of the body and has a mutated… »
A drug that is used to treat certain skin conditions and is being studied in the treatment of cutaneous (skin-related) T-cell cancer… »
A dual peroxisome proliferator-activated receptor (PPAR) agonist, with hypoglycemic activity. Aleglitazar binds to both PPARalpha and PPARgamma and decreases plasma levels of… »
A type of monoclonal antibody used in the treatment of leukemia. Monoclonal antibodies are laboratory-produced substances that can locate and bind to… »
A drug used to treat certain bone conditions, such as osteoporosis and Paget disease of the bone. It is also being studied… »
A second generation bisphosphonate and synthetic analog of pyrophosphate with anti-bone-resorption activity. Alendronic acid binds to and inhibits the activity of farnesyl… »
The l-alanine ester form of estramustine, a combination of the nitrogen mustard normustine coupled via a carbamate to estradiol, with antineoplastic… »
A leukemia characterised by the absence of leukemic cells in the peripheral blood. -- 2003 »
A form of aleukemic leukemia where lesions containing abnormal leukocytes can be found within the skin. »
Aleutian - a person having origins from the Aleut indigenous group of Alaska and their descendants and who maintains tribal affiliation, or… »
Any of series of proprietary fluorescent dyes that span the visible spectrum. They are typically used as cell and tissue labels in… »
A rare genetic neurodegenerative disorder which belongs to the group of leukodystrophies. It has a slow and progressive clinical course and is… »
A synthetic short-acting opioid with analgesic and local anesthesia enhancing activity. Alfentanil primarily binds to mu-opioid receptor, a G-protein-coupled receptor, thereby mimicking… »
The hydrochloride salt of alfentanil, a synthetic short-acting opioid with analgesic and local anesthesia enhancing activity. Alfentanil primarily binds to mu-opioid receptor,… »
A synthetic quinazoline compound with smooth muscle relaxing activity. Alfuzosin selectively binds to and antagonizes alpha-1-adrenergic receptors in smooth muscle of the… »
The hydrochloride salt of alfuzosin, a quinazoline compound with smooth muscle-relaxing activity. Alfuzosin selectively binds to and antagonizes post-synaptic alpha-1-adrenoreceptors in smooth… »
Chlorophyll-containing, mainly aquatic eukaryotic organisms lacking true stems and roots and leaves. »
A cancer vaccine comprised of irradiated allogeneic pancreatic cancer cells transfected to express murine alpha-1,3-galactosyltransferase with potential antitumor activity. Vaccination is associated… »
A country in northern Africa, bordering the Mediterranean Sea, between Morocco and Tunisia. »
A defined procedure for solving a problem. Applied to a problem-solving procedure implemented in software to be executed by a computer. … »
A benign (not cancer) condition in which there are more cells than normal in the breast lobules and the cells look abnormal… »
An artifact that occurs when the scanned body part is larger than field of view (FOV) such that portions of the object… »
The act of adjusting or aligning objects in relation to each other; the result of this activity. »
A quinolinone sulfooxime and inhibitor of Na-K-Cl cotransporters 1 and 2 with diuretic activity. »
A drug used alone or with another drug to treat certain types of non-small cell lung cancer and malignant pleural mesothelioma. It… »
A hydrazide derivative of m-sulfamoylbenzoic acid with diuretic activity. Alipamide primarily causes a saluretic effect and is able to inhibit carbonic anhydrase… »
Pertaining to a portion of the whole; any one of two or more samples of something, of the same volume or… »
A second-generation, orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase Aurora A kinase with potential antineoplastic activity. Alisertib… »
An orally active nonpeptide renin inhibitor with antihypertensive activity. Aliskiren selectively binds to the S3 sub-pocket of renin, an enzyme in the… »
An orally active nonpeptide renin inhibitor with antihypertensive activity. Aliskiren selectively binds to the S3 sub-pocket of renin, an enzyme in the… »
A species of strictly anaerobic, Gram negative, rod shaped bacteria assigned to the phylum Bacteroidetes. This bacteria is non-motile, hemolytic, hydrolyzes gelatin,… »
An orally- and topically-active naturally-occurring retinoic acid with antineoplastic, chemopreventive, teratogenic, and embryotoxic activities. Alitretinoin binds to and activates nuclear retinoic acid… »
A substituted benzamide that acts as a dopamine receptor antagonist with antiemetic properties. »
A fluorescence in situ hybridization kit that detects the rearrangements between the ALK gene which is located at 2p23 and all known… »
A gene that makes a protein called anaplastic lymphoma kinase (ALK), which may be involved in cell growth. Mutated (changed) forms of… »
An orally available inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with antineoplastic activity. Upon administration, ALK inhibitor CH542480 binds… »
An orally available inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with antineoplastic activity. Upon administration, ALK inhibitor RO5424802 binds… »
An orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration,… »
Heart formation is cued by a combination of positive and negative signals from surrounding tissues. Inhibitory signals that block heart formation… »
ALK tyrosine kinase receptor (1620 aa, ~176 kDa) is encoded by the human ALK gene. This protein is involved in ligand binding,… »
Human ALK wild-type allele is located within 2p23 and is approximately 729 kb in length. This allele, which encodes ALK tyrosine kinase… »
An orally available dual kinase inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) and focal adhesion kinase (FAK), with potential… »
A usually aggressive large B-cell lymphoma characterized by the presence of monomorphic immunoblast-like neoplastic B-lymphocytes in a sinusoidal growth pattern. The… »
A chemical that can dissolve in water, combine with acids to form salts, and make acids less acidic. Alkalis have a bitter… »
A substance which, when added to water, decreases the hydrogen-ion concentration; a solution containing a base, a substance that combines with a… »
Alkaline ceramidase 1 (264 aa, ~31 kDa) is encoded by the human ACER1 gene. This protein is involved in the catabolism of… »
Alkaline ceramidase 2 (275 aa, ~31 kDa) is encoded by the human ACER2 gene. This protein plays a role in ceramide metabolism… »
Alkaline ceramidase 3 (267 aa, ~32 kDa) is encoded by the human ACER3 gene. This protein is involved in the synthesis of… »
An enzyme that catalyses the cleavage of inorganic phosphate non-specifically from a wide variety of phosphate esters and having a high (greater… »
A quantitative measurement of alkaline phosphatase present in a sample. »
The determination of the ratio of alkaline phosphatase compared to creatinine present in a sample. The measurement may be expressed as a… »
Alkaline phosphatase, placental type (535 aa, ~58 kDa) is encoded by the human ALPP gene. This protein plays a role in phosphate… »
Alkaline phosphatase, tissue-nonspecific isozyme (524 aa, ~57 kDa) is encoded by the human ALPL gene. This protein may play a role in… »
Refers to the amount of alkali. An alkali is a chemical that can dissolve in water, combine with acids to form… »
A process that lowers the amount of acid in a solution. In medicine, an alkali, such as sodium bicarbonate, may be given… »
Used topically or systemically for management of metabolic acidosis, improved muscle contraction, and hyper-acidic conditions, Alkalinizing Agent Preparations contain one or more… »
A member of a large group of substances found in plants and in some fungi. Alkaloids contain nitrogen and can be made… »
An abnormally high alkalinity (low hydrogen-ion concentration) of the blood and other body tissues. »
A rare autosomal recessive disorder characterized by abnormalities in the metabolism of phenylalanine and tyrosine. It results in the accumulation in the… »
This gene plays a role in oxidation. »
Human ALKBH7 wild-type allele is located in the vicinity of 19p13.3 and is approximately 3 kb in length. This allele, which encodes… »
A drug that is used to treat multiple myeloma and ovarian epithelial cancer and is being studied in the treatment of other… »
A drug used to treat multiple myeloma in patients who cannot take melphalan by mouth. It is also being studied in the… »
A drug used to treat multiple myeloma. It is also used to treat ovarian epithelial cancer that cannot be removed by… »
A substance that inhibits Alkyl-Guanine Transferase, an enzyme involved with DNA repair. »
A type of drug that is used in the treatment of cancer. It interferes with the cell's DNA and inhibits cancer cell… »
Acute myeloid leukemias and myelodysplastic syndromes arising as a result of the mutagenic effect of alkylating agents that are used for the… »
A disorder seen following cancer chemotherapy. It is the most common cause of therapy-related myelodysplastic syndromes. It typically manifests several years after… »
Alkylating Activity in biological systems is typically a process of covalent bonding in which a chemical substance replaces hydrogen atom(s) in biologically… »
An ether-linked lysophosphatidylcholine with potential antineoplastic activity. Exhibiting anti-proliferative and immunomodulatory properties, alkyl-phosphocholine compounds modulate cell membrane permeability, phospholipid metabolism, and… »
An ester of alkane sulfonic acid that acts as an alkylating agent. »
Alkyltransferases and Aryltransferases are classes of enzymes that transfer an alkyl or aryl chemical group from one compound (the donor) to another… »
An aggressive (fast-growing) type of leukemia (blood cancer) in which too many lymphoblasts (immature white blood cells) are found in the blood… »
A response indicating that something happens or happened all of the time. »
A type of class comparison used when more than two classes are present in which each class is compared individually to each… »
A nutrient that the body needs in small amounts to function and stay healthy. All-trans retinoic acid is made in the body… »
An umbilical cyst that arises from allantoic tissue that did not regress during gestational development. Most cases involve a patent urachus that… »
A drug used to treat certain allergy symptoms. It blocks a chemical released during an allergic response that causes itching, sneezing, runny… »
Mutually exclusive alternative forms of the same gene occupying the same locus on homologous chromosomes, differing in nucleotide sequence and governing the… »
Different mutations in the same gene that cause different phenotypic manifestations or severity of disease. »
Any variance from the expected 1:1 ratio for the expression of the two inherited parental alleles for the same gene. »
The examination of the extent and variation of allelic loss in polymorphic DNA markers within a sample. »
A substance that causes an allergic response. Examples include pollen, molds, and certain foods. »
The ratio measurement of the allergen wheal size to the positive control wheal size in an allergen skin test. »
The semiquantitative assessment of the wheal-and-flare index that measures the intensity of the reaction. »
An immune reaction to aspergillus in patients usually suffering from asthma or cystic fibrosis. »
An inflammatory skin condition caused by an immune response to direct contact between the skin and an allergen. It consists of a… »
Vasculitis due to allergic reaction, marked by such cutaneous lesions as papules, macules, vesicles, urticarial wheals, purpura, and small ulcers, and accompanied… »
Dermatitis caused by an allergic reaction to arnica. »
A hypersensitive immune reaction to a substance that normally is harmless or would not cause an immune response in most people. An… »
Inflammation of the nasal mucous membranes caused by an IgE-mediated response to external allergens. The inflammation may also involve the mucous membranes… »
An allergy is a reaction by your immune system to something that does not bother most other people. People who have allergies… »
The inflammatory response associated with asthma is characterized by the recruitment of eosinophils from the bronchial microcirculation in response to the regulated… »
The injection of an allergen extract intended to increase resistance, tolerance, or immunity to the given allergens. When the allergen extract is… »
A biological potency unit assigned to several standardized allergenic extracts, following in-vitro comparison of the test extract to an FDA CBER reference… »
Unit of measure of potency of allergenic product expressed as a number of allergy units per one milliliter of formulation. »
A rare genetic syndrome with an autosomal recessive pattern of inheritance. It is caused in some cases by mutations in the AAAS… »
The Alliance for Lung Cancer Advocacy, Support and Education is a nonprofit organization based in Vancouver, Washington, founded to improve the quality… »
Professional health-care providers who are not physicians, especially medical assistants, technicians, and therapists but not nurses. (dictionary.com) »
Occupations of medical personnel who are not physicians, and are qualified by special training and, frequently, by licensure to work in supporting… »
Occupations of medical personnel who are not physicians, and are qualified by special training and, frequently, by licensure to work in supporting… »
Garlic plants are closely related to and similar to onions and they have a similar, but stronger odor. The leaves of garlic… »
The distribution of resources over various time periods, products, operations, or investments. »
A coded value specifying the method of assigning entities to groups or categories. »
An antimitotic agent that binds to tubulin and inhibits tubulin polymerization and arrests proliferation of tumor cells. »
A copper(l) complex used as an antiinflammatory drug and antiarthritic agent. »
Allodepleted haploidentical T-lymphocytes transduced with the Gal-V pseudotyped retrovirus vector encoding SFG.iCasp9-2A-deltaCD19, with potential immune reconstitution property. SFG.iCasp9-2A-deltaCD19 contains the suicide gene… »
Taken from different individuals of the same species. Also called allogenic. »
A population of allogeneic cytotoxic T-lymphocytes (CTLs) specifically reactive to human adenovirus (Ad) with potential immunomodulating and anti-adenoviral activities. Upon immunoprophylactic adoptive… »
A cancer vaccine consisting of allogeneic, immortalized dendritic precursor cells derived from a patient with acute myelogenous leukemia (AML), with potential immunostimulatory… »
An allogeneic whole cell vaccine, derived from irradiated allogenic tumor cells manipulated to express human B7.1 (CD80 antigen) and human leukocyte antigen… »
A procedure in which a person receives stem cells (cells from which all blood cells develop) from a genetically similar, but not… »
A preparation of allogeneic Epstein-Barr virus (EBV)- and human cytomegalovirus (CMV)-specific CD8+ central memory-derived T effector-lymphocytes that have been genetically modified to… »
A preparation consisting of allogeneic, differentiated Th1-like T cells bound to T cell-stimulating monoclonal antibodies with potential antitumor activity. More specifically, allogeneic… »
A population of allogeneic lymphocytes expressing the CD56 surface antigen and exhibiting a lack of CD3, with immunomodulating activity. Upon infusion of… »
A population of allogeneic cytotoxic T lymphocytes (CTLs) specifically reactive to cytomegalovirus (CMV) and adenovirus (AdV) with potential antiviral activity. Allogeneic CMV/AdV-specific… »
A preparative treatment regimen given prior to a cell transplantation from a genetically non-identical donor. The regimen consists of chemotherapy with or… »
A population of allogeneic cytotoxic T lymphocytes (CTLs) specifically reactive to the herpes virus cytomegalovirus (CMV) with potential immunomodulating and antiviral… »
A cancer vaccine consisting of allogeneic, immortalized dendritic cells (DCs) loaded with tumor specific antigens and activated, with potential immunostimulatory and antineoplastic… »
A cell-based vaccine composed of allogeneic dendritic cells pulsed ex-vivo with an autologous myeloma idiotype with potential antineoplastic activity. Upon administration, allogeneic… »
A preparation of allogeneic Epstein-Barr virus (EBV) specific cytotoxic T-lymphocytes (CTL) with potential antineoplastic activity. The allogeneic EBV-specific CTLs are either harvested… »
A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysates from an allogeneic glioblastoma (GBM) stem-like cell line, with… »
An allogeneic tumor cell vaccine containing myeloma cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene with potential antineoplastic activity. Upon… »
An allogenic vaccine consisting of irradiated breast cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene. Upon vaccination, the genetically modified… »
An allogeneic cancer vaccine composed of lethally irradiated whole melanoma cancer cells that are genetically modified to secrete the immunostimulatory cytokine granulocyte-macrophage… »
An allogeneic cancer vaccine composed of lethally irradiated, whole pancreatic cancer cells transfected with a plasmid carrying the gene for cytokine granulocyte-macrophage… »
An allogeneic cancer vaccine composed of lethally irradiated, whole pancreatic cancer cells transfected with a plasmid carrying the gene for cytokine granulocyte-macrophage… »
A clinical treatment in which hematopoietic stem cells (HSCs) are transferred from one genetically dissimilar individual to another. »
An allogeneic melanoma cell vaccine derived from a cell line with high expression of melanoma associated antigens and genetically modified to express… »
Allogeneic IL13-Zetakine/HyTK-Expressing-Glucocorticoid Resistant Cytotoxic T Lymphocytes GRm13Z40-2
A preparation of glucocorticoid receptor (GR) negative, allogeneic cytotoxic T-lymphocytes (CTLs) expressing a membrane-tethered interleukin 13 (IL13) cytokine chimeric T-cell antigen receptor… »
An allogeneic cancer vaccine composed of a mixture of lethally irradiated whole melanoma cancer cells obtained from four different melanoma cell lines,… »
A cancer vaccine, containing human-specific large multivalent immunogens (LMIs) isolated from the membrane fraction of cells from a breast cancer cell line,… »
A cancer vaccine, containing human-specific large multivalent immunogen (LMI) isolated from plasma membrane fractions of the melanoma cell lines MSM-M1 and MSM-M2,… »
A preparation of cytotoxic T-lymphocytes (CTL), specifically reactive to the Epstein-Barr virus (EBV) latent membrane proteins (LMP) 1 and 2, with potential… »
A cell that is antigenically distinct from other lymphocytes. »
A cancer vaccine derived from two gentically modified human melanoma cell lines with potential antineoplastic activity. Allogeneic melanoma vaccine AGI-101H consists of… »
A biologic product that consists of undifferentiated stem cells, obtained from adult bone marrow or other non-embryonic tissue sources, that are expanded… »
A population of allogeneic, cytotoxic natural killer (NK) cells with potential antitumor activity. Allogeneic natural killer cell line MG4101 is derived from… »
A whole cell vaccine comprised of irradiated allogeneic renal cell carcinoma (RCC) with potential immunostimulating and antineoplastic activities. Allogeneic renal cell carcinoma… »
A procedure in which a person receives blood-forming stem cells (cells from which all blood cells develop) from a genetically similar, but… »
Allogeneic, T-lymphocytes with potential immune reconstitution activity. Donor T-lymphocytes are transduced with a retroviral vector (BPZ-1001) encoding the inducible suicide gene caspase… »
A vaccine composed of tumor cells isolated from the tumor of one patient, killed and processed, and administered to another patient to… »
A vaccine composed of killed glioma cancer cells from another patient for use in immunotherapy. »
A measure of the genetic difference between individuals or organisms. It is a factor in determining if transplants are likely to… »
The transplant of an organ, tissue, or cells from one individual to another individual of the same species who is not an… »
After transplantation of organ allografts, there are two pathways of antigen presentation. In the direct pathway, recipient T cells react to intact… »
Grafting or transplanting cells, tissues, or organs between genetically non-identical individuals. »
Alloimmunization is an immune response to foreign (donor) antigens. »
A system in which medical doctors and other healthcare professionals (such as nurses, pharmacists, and therapists) treat symptoms and diseases using drugs,… »
A drug that lowers high levels of uric acid (a byproduct of metabolism) in the blood caused by some cancer treatments. … »
The sodium form of allopurinol, which is a structural isomer of hypoxanthine. Allopurinol inhibits xanthine oxidase, an enzyme that converts oxypurines to… »
A substance that is being studied as a gene therapy agent in the treatment of cancer. It increases the ability of the… »
An isothiocyanate with an allyl group (-C-C=C). The chemical structure is C=CCN=C=S. »
An allyl-S compound with the structure S-C=C-C. »
An allyl-S compound with the structure C=CCSCC=C. »
A class of compounds with at least one allyl group (-C=C-C) attached to a sulfur atom. »
A characteristic of a medicinal product, specifying that its most predominant agreeable savor detected by the unified sensation of taste and olfactory… »
The oil extracted from the seed fruits of Prunus amygdalus. Almond oil is typically used as a skin emollient and for… »
A subjective answer that something rarely happens. »
A sulfonamide triptan with extracerebral, intracranial vasoconstrictor activity. Almotriptan selectively binds to and activates serotonin 5-HT 1B and 1D receptors in the… »
The malate salt of almotriptan, a sulfonamide triptan with vasoconstrictor activity. Almotriptan selectively binds to and activates serotonin 5-HT 1B and 1D… »
A synthetic muramyl dipeptide (MDP) analogue with potential immunostimulating and antineoplastic activity. As a derivative of the mycobacterial cell wall component MDP,… »
A benzopyran lacking the indole ring of the triptans with vasoconstrictor activity. Alnitidan selectively binds to and activates serotonin 5-HT 1B and… »
A succulent, fibrous plant, of the family Liliaceae, with basal leaves, having toothed or fibrous margins. Native to southern Africa, it is… »
A preparation of leaf pulp from the parenchymal tissue of the plant Aloe vera (Liliaceae). Aloe vera gel contains carbohydrate polymers, such… »
A substance found in certain plants, including aloe vera. It belongs to a family of compounds called anthraquinones, which have shown anti-inflammatory… »
A herbal-based mouthrinse containing aloe, anise, ascorbic acid, clove, peppermint, spearmint and thyme, with potential anti-mucositic activity. When aloe/anise/ascorbic acid/clove/peppermint/spearmint/thyme-based mouthwash is… »
A selective, orally bioavailable, pyrimidinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. In addition to its effect on glucose levels,… »
The benzoate salt form of alogliptin, a selective, orally bioavailable, pyrimidinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. In addition… »
The lack or loss of hair from areas of the body where hair is usually found. Alopecia can be a side effect… »
A rare dermatologic disorder characterized by the accumulation of mucinous material in the hair follicles. In some cases it is associated with… »
A potent and selective 5-HT3 receptor antagonist. Alosetron blocks the actions of serotonin at 5-HT3 sites in the peripheral nervous system, particularly… »
The hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. Alosetron blocks the actions of serotonin at 5-HT3 sites… »
This gene plays a role in oxidation of fatty acids. »
Human ALOX12 wild-type allele is located in the vicinity of 17p13.1 and is approximately 15 kb in length. This allele, which encodes… »
This gene is involved in fatty acid oxidation. »
Human ALOX12B wild-type allele is located in the vicinity of 17p13.1 and is approximately 15 kb in length. This allele, which encodes… »
This gene is involved in hormonal signaling and inflammation. »
Human ALOX15 wild-type allele is located in the vicinity of 17p13.3 and is approximately 11 kb in length. This allele, which encodes… »
This gene plays a role in inflammation. »
Human ALOX5 wild-type allele is located in the vicinity of 10q11.2 and is approximately 72 kb in length. This allele, which encodes… »
A drug used to prevent nausea and vomiting caused by chemotherapy. It is also used to prevent nausea and vomiting after… »
A rare genetic syndrome with an autosomal recessive pattern of inheritance. It is caused by a mutation in the gene for the… »
Alpha 2B adrenergic receptor protein (450 aa, 50 kD) is a cell communication process protein that is encoded by the human ADRA2B… »
Expressed by Alpha Adrenergic Receptor Genes in effector tissues innervated by postganglionic sympathetic adrenergic fibers, Alpha Adrenergic Receptors are one of two… »
Expressed in effector tissues innervated by postganglionic sympathetic adrenergic fibers, Alpha Adrenergic Receptor Genes encode Alpha Adrenergic Receptors, one of two major… »
A cell in the periphery of the pancreatic islets that secretes glucagon. »
Members of the Alpha-Chemokines are referred to also as the 4q chemokine family because the genes encoding members of this family map… »
Therapy that uses a radioactive substance that gives off a type of high-energy radiation called an alpha-particle to kill cancer cells. The… »
The determination of the amount of the alpha fetoprotein activity present in a sample. »
A vaccine consisting of a recombinant adenoviral vector encoding alpha fetoprotein. After vaccination, expressed alpha fetoprotein may stimulate a cytotoxic T lymphocyte… »
The determination of the amount of alpha fetoprotein L1 present in a sample. »
The determination of the amount of alpha fetoprotein L2 present in a sample. »
The determination of the amount of alpha fetoprotein L3 present in a sample. »
The determination of the ratio of alpha fetoprotein L3 compared to total alpha fetoprotein present in a sample. The measurement may be… »
A vaccine consisting of plasmid DNA encoding alpha fetoprotein. After vaccination, expressed alpha fetoprotein may stimulate a cytotoxic T lymphocyte (CTL) response… »
A potent alpha galactosylceramide modified from marine-sponge that stimulates the immune system to exhibit antitumor activity. »
The determination of the amount of alpha glucuronidase present in a sample. »
The determination of the amount of alpha glutathione-s-transferase present in a sample. »
The determination of the ratio of alpha glutathione-s-transferase compared to creatinine present in a sample. The measurement may be expressed as a… »
Granules found in several types of cells, especially platelets, where they are the most numerous type of granule; contain secretory proteins. … »
A clonal disorder, also known as immunoproliferative small intestinal disease or Mediterranean lymphoma, characterised by the secretion of a defective alpha heavy… »
A right-handed spiral conformation; the a-helix has a pitch of 5.4 A and has 3.6 amino acid residues per turn; every main… »
One of a group of substances that are found in several types of fruit and in milk. They are used in skin… »
The determination of the amount of alpha-hydroxybutyrate dehydrogenase present in a sample. »
One of a group of substances that are found in several types of fruit and in milk. They are used in skin… »
A cytochemical staining technique used to detect alpha-naphthyl acetate esterase (ANAE) activity. Nonspecific esterase stains with acetate substrate and is mainly used… »
A cytochemical staining technique used to detect esterase enzyme contained within monocytes and macrophages, which reacts strongly with the substrate alpha-naphthyl… »
A cytochemical staining technique using the alpha-naphthyl esterase staining method or a nonspecific esterase staining method to identify and quantify monoblasts and… »
unstable isotopes of high atomic number (elements of mass number from 82 up) which energetically release from their nuclei a particle consisting… »
An emission of positively charged particles composed of two protons and two neutrons, i.e., helium nuclei, emitted during disintegration of very heavy… »
A genetic hematologic disorder characterized by partial or complete absence of the alpha globin chains of the heme molecule. »
A condition in which a person has reduced protein production from one of the four alpha-globin alleles. »
A condition in which a person has reduced protein production from two of the four alpha-globin alleles. »
The determination of the amount of the alpha tocopherol in a sample. »
The determination of the ratio of alpha-tocopherol compared with the total vitamin E in a sample. The measurement may be expressed as… »
An angiogenesis inhibitor that acts by blocking the action of alpha(v)beta integrins. An alpha(v)beta integrin inhibitor blocks the activity of an endothelial… »
Alpha-(1,3)-fucosyltransferase (530 aa, ~60 kDa) is encoded by the human FUT4 gene. This protein is involved in the generation of fucosylated carbohydrate… »
The determination of the amount of alpha-1 acid glycoprotein present in a sample. »
A genetic disorder characterized by decreased alpha-1 antitrypsin activity in the lungs and blood and deposition of alpha-1 antitrypsin protein in the… »
The determination of the amount of alpha-1 antitrypsin present in a sample. »
The determination of the amount of alpha-1 globulin present in a sample. »
The determination of the ratio of alpha-1 globulin compared to total protein present in a sample. The measurement may be expressed as… »
The determination of the amount of alpha-1 microglobulin present in a sample. »
The determination of the ratio of alpha-1 microglobulin compared to creatinine present in a sample. The measurement may be expressed as a… »
Alpha-1-antitrypsin (418 aa, ~47 kDa) is encoded by the human SERPINA1 gene. This protein plays a role in regulation of proteolysis. … »
Human serum-derived alpha-1 proteinase inhibitor (alpha-1-antitrypsin or AAT) with immunomodulating and anti-inflammatory activity. Upon administration, AAT reduces the production of proinflammatory cytokines,… »
An allogeneic lung cancer vaccine with potential immunostimulating and antineoplastic activities. Derived from allogeneic lung tumor cells, alpha-1,3-galactosyltransferase-expressing allogeneic lung tumor cell… »
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (478 aa, ~56 kDa) is encoded by the human MGAT4C gene. This protein is involved in protein glycosylation. … »
Alpha-1A adrenergic receptor (466 aa, 51 kD) is a cell division process protein that is encoded by the human ADRA1A gene and… »
Alpha-1B adrenergic receptor (520 aa, 57 kD) is a cell division process protein that is encoded by the human ADRA1B gene and… »
The determination of the amount of the alpha-2 antiplasmin in a sample. »
The two-letter country codes specified by the ISO 3166-1 country code standard. »
The determination of the amount of alpha-2 globulin present in a sample. »
The determination of the ratio of alpha-2 globulin compared to total protein present in a sample. The measurement may be expressed as… »
The determination of the amount of alpha-2 macroglobulin present in a sample. »
Alpha-2-macroglobulin (1474 aa, ~163 kDa) is encoded by the human A2M gene. This protein has activity as a protease inhibitor. »
Alpha-2A Adrenergic Receptor (450 aa, 49 kD) is a cell motility protein that is encoded by the human ADRA2A gene and has… »
Alpha-2C adrenergic receptor (462 aa, ~50 kDa) is encoded by the human ADRA2C gene. This protein is involved in catecholamine-induced regulation of… »
The three-letter country codes specified by the ISO 3166-1 country code standard. »
Natural or synthetic Alpha-adrenergic Agonists selectively bind to and activate alpha adrenergic receptors of the sympathetic nervous system, mimicking the actions of… »
A substance that relaxes muscle tissue in blood vessels and in the prostate gland, which improves the flow of urine and… »
A family of hydrolases that cleaves alpha-linkages in polysaccharides, such as starch and glycogen, and yield glucose and maltose. This family includes… »
Any monoclonal antibody directed against an alpha-beta T-Cell receptor. »
A substance that relaxes muscle tissue in blood vessels and in the prostate gland, which improves the flow of urine and… »
Carotenoid consisting of a cyclic structure on each end with additional double bonds at the number 5 and 4' carbon atoms of… »
The monohydrate form of the alpha isoform of D-glucopyranose, a synthetic simple monosaccharide that is used as an energy source. D- glucopyranose… »
Alpha-enolase (434 aa, ~47 kDa) is encoded by the human ENO1 gene. This protein is involved in glycolysis and tumor suppression, and… »
A protein normally produced by a fetus. AFP levels are usually undetectable in the blood of healthy adult men or women (who… »
The determination of the amount of alpha-fetoprotein present in a sample. »
A cell-based cancer vaccine comprised of autologous dendritic cells pulsed with four alpha-fetoprotein (AFP) peptides, with potential immunostimulatory and antineoplastic activities. Upon… »
A preparation of glycosphingolipids (GSL), containing the disaccharide epitope galactose-alpha-1,3-galactose (alpha-Gal), with potential antineoplastic activity. Upon intratumoral injection, alpha-Gal glycosphingolipids may stimulate… »
A cancer vaccine comprised of autologous dendritic cells (DCs) pulsed with the marine sponge glycolipid alpha-galactosylceramide (alpha-GalCer) with potential immunostimulatory and antimetastatic… »
Alpha-globin transcription factor CP2 (502 aa, ~57 kDa) is encoded by the human TFCP2 gene. This protein plays a role in transcriptional… »
A type of globulin in plasma that in electrically charged solutions exhibits greatest colloidal mobility among that of serum globulins. »
A bacterium that is assigned to the genus Streptococcus that is able to reduce the iron content in hemoglobin in red blood… »
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7 (221 aa, ~25 kDa) is encoded by the human ALKBH7 gene. This protein plays a role in… »
Alpha-ketoglutarate-dependent dioxygenase FTO (505 aa, ~58 kDa) is encoded by the human FTO gene. This protein is involved in the demethylation of… »
Alpha-lactalbumin (142 aa, ~16 kDa) is encoded by the human LALBA gene. This protein plays a role in the regulation of lactose… »
A substance that is being studied for its ability to protect normal cells from the side effects of chemotherapy and prevent peripheral… »
A proprietary water- and lipid-soluble polymer-based nutritional supplement composed of a complex mixture of alpha-lipoic acid bound to palladium (Palladium Lipoic Acid… »
An autosomal recessive lysosomal storage disease characterized by deficient activity of the enzyme alpha-D-mannosidase. There is a wide range of signs and… »
Alpha-methylacyl-CoA racemase (382 aa, ~42 kDa) is encoded by the human AMACR gene. This protein plays a role in the beta-oxidation of… »
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 protein (336 aa, ~38 kDa) is encoded by the human ST6GALNAC5 gene. This protein plays a role in regulation… »
A selective cytochemical monocyte marker. »
A selective cytochemical monocyte marker for alpha-naphthyl butyrate at pH 6.1. Alpha-naphthyl butyrate covers the external surface of the plasma membrane in… »
Alpha-synuclein (140 aa, ~14 kDa) is encoded by the human SNCA gene. This protein plays a role in the modulation of presynaptic… »
Alpha-taxilin (546 aa, ~62 kDa) is encoded by the human TXLNA gene. This protein is involved in vesicular trafficking. »
A purine analog with potential antineoplastic activity. »
A nutrient that the body needs in small amounts to stay healthy and work the way it should. It is fat-soluble (can… »
Alpha-tubulin N-acetyltransferase (421 aa, ~47 kDa) is encoded by the human ATAT1 gene. This protein is involved in protein acetylation that may… »
A mature polarized dendritic cell with potent immunostimulating activity. Treating dendritic cells (DCs) with interferon-alpha (IFN-a) and polyinosinic:polycytidylic acid (p-I:C) in addition… »
The significance level for the detection p-value in an absolute analysis. »
The second significance level for the detection p-value in an absolute analysis. »
A term used to describe a character string containing only letters and numbers. »
The hydrochloride salt form of alphaprodine, a synthetic piperidine ester, with opioid analgesic activity. Alphaprodine mimics the actions of endogenous neuropeptides by… »
An rna-type retrovirus with a c-type morphology. The viruses have a widespread distribution and include both exogenous (vertical and horizontal transmission) and… »
A genus of enveloped, spherical, or pleomorphic viruses with T=4 icosahedral symmetry, in the family Togaviridae. The genome is composed of a… »
Human ALPL wild-type allele is located in the vicinity of 1p36.12 and is approximately 69 kb in length. This allele, which encodes… »
A genetic syndrome usually inherited as an X-link trait. It is caused by abnormalities in the COL4A5 gene. It affects males more… »
Human ALPP wild-type allele is located in the vicinity of 2q37 and is approximately 4 kb in length. This allele, which encodes… »
A drug used to treat anxiety disorders and panic attacks. It is being studied in the treatment of nausea and vomiting caused… »
The determination of the amount of alprazolam present in a sample. »
A drug that is used to treat impotence (inability to have an erection) and is being studied in the treatment of sexual… »
A rare autosomal recessive syndrome caused by mutations in the gene ALMS1. Signs and symptoms include blindness, obesity, hearing loss, endocrine abnormalities,… »
A procedure in which mild electric currents are applied to certain acupuncture points (spots on the body where an acupuncture needle may… »
A form of tissue plasminogen activator that is made in the laboratory. It helps dissolve blood clots and is used to treat… »
A change resulting in something that is different from the original. »
Pertaining to or characterized by cognition. That operation of the mind which we become aware of objects of thought or perception; it… »
A backup sequence of characters used to identify a study. »
Alternate Splicing is a process in which multiple protein isoforms or products are generated from a single gene as a result of… »
A backup sequence of characters used to identify a study. »
Available in place of something else. »
The complement system of plasma proteins is an important part of the immune system that forms a cascade of factors that lyses… »
A procedure in which hematopoietic stem cells are given for another reason, not to reconstitute the patient's immune system. »
Treatment used instead of, or supplementary to, conventional Western-based practices. Alternative medicine includes treatments and practices such as acupuncture, holistic medicine, homeopathy,… »
NIH: Major category of Complementary and Alternative Medicine classification. This category involves complete systems of theory and practice that are alternatives… »
Treatments that are used instead of standard treatments. Standard treatments are based on the results of scientific research and are currently accepted… »
Any medical substance or procedure not generally accepted by orthodox western medicine or an unorthodox application of an otherwise accepted substance or… »
Medical substance or procedure in the process of becoming accepted by orthodox western medicine. »
An electric generator designed to produce an alternating current. »
An agent, also known as altizide, belonging to the class of thiazide diuretics with antihypertensive activity. »
A device designed to measure height above the ground. »
A high elevation plateau in southeastern Peru and western Bolivia, elevation about 3500 m. »
A period of high temperature; a postglacial thermal optimum. »
An anticancer drug that belongs to the family of drugs called alkylating agents. »
A chemical substance that contains aluminum sulfate and a second chemical, usually potassium sulfate. It is used to shrink tissues, to stop… »
A metallic element that is found combined with other elements in the earth’s crust. It is also found in small amounts… »
A topical astringent that is used as an antiseptic agent. Aluminum acetate is used to treat inflammation, itching, and stinging of the… »
Aluminum ion requiring three electrons to return to its elemental state. »
An aluminum salt formulation of clofibrate, an aryloxyisobutyric acid derivate with antihyperlipidemic activity. »
An inorganic compound containing aluminum. Used in various immunologic preparations to improve immunogenicity, aluminum hydroxide adjuvant consists of aluminum hydroxide gel… »
A topical astringent that is used as an antiseptic agent. Aluminum lactate is used to treat inflammation, itching, and stinging of the… »
A salt or hydroxide mixture of aluminum and magnesium metals used as an antacid, aluminum magnesium absorbs and neutralizes stomach acid, helping… »
A measurement of aluminum present in a sample. »
The aluminum salt of the fatty acid, stearic acid. »
A type of immune adjuvant (a substance used to help boost the immune response to a vaccine). »
An aluminum salt with immune adjuvant activity. This agent adsorbs and precipitates protein antigens in solution; the resulting precipitate improves vaccine immunogenicity… »
A drug used to treat non-small cell lung cancer that has spread to other parts of the body and has a mutated… »
A derivative of the Canarypox Virus, ALVAC can infect mammalian cells but it can't replicate. Thus, it produces a self-limiting infection… »
A derivative of the Canarypox Virus, ALVAC can infect mammalian cells but it can't replicate. Thus, it produces a self-limiting infection… »
A cancer vaccine consisting of ALVAC, a highly attenuated poxvirus strain derived from the canarypox virus. ALVAC-B7-CEA expresses carcinoembryonic antigen (CEA),… »
A cancer vaccine consisting of ALVAC, a highly attenuated poxvirus strain derived from the canarypox virus. ALVAC-CEA (6D)-B7.1 vaccine expresses both… »
A replication-defective recombinant canarypox virus (ALVAC) that contains the entire human carcinoembryonic antigen (CEA) gene. Vaccination with ALVAC-CEA (VCP248) may stimulate… »
A cancer vaccine that uses a viral vector system derived from the canarypox virus engineered to target the carcinoembryonic antigen (CEA). It… »
A cancer vaccine made with a form of the canarypox virus that does not cause disease in people. It is being studied… »
A cancer vaccine consisting of a replication-defective recombinant canarypox virus (ALVAC) encoding the cancer-testis antigen NY-ESO-1, with potential immunostimulatory and antineoplastic… »
A vaccine comprise of a canarypox viral vector that carries the gene for human B7.1 (CD80 antigen) with potential use as an… »
A cancer vaccine containing a replication-defective recombinant canarypox virus (ALVAC), encoding an epitope of MART-1 (melanoma antigen recognized by T-cells), with potential… »
A therapeutic cancer vaccine, based on a replication-defective recombinant canarypox virus (ALVAC) encoding multiple melanoma antigens, with potential immunostimulatory and antineoplastic… »
A cancer vaccine consisting of a replication-defective recombinant canarypox virus [ALVAC(2)] encoding the cancer-testis antigen NY-ESO and the TRIad of COstimulatory Molecules… »
A benign, well circumscribed lung neoplasm morphologically characterized by the presence of cystic spaces resembling alveoli, lined by a simple cuboidal… »
A branch of the maxillary artery that is found in the gingiva, premolars, and molars. »
A rare lethal congenital abnormality that refers to the abnormal development of the capillaries around the alveoli in the lung parenchyma. It… »
A cell found in the walls of the pulmonary alveoli; the term is limited to alveolar epithelial cells (type I and type… »
A flattened cell of the alveolar epithelium, distinguished by their greatly attenuated cytoplasm and paucity of organelles. »
A pleomorphic cell of the pulmonary alveolar epithelium that secretes surfactant and is distinguished by abundant cytoplasm containing numerous lipid-rich multilamellar… »
The respiratory passage distal to the respiratory bronchiole. Alveolar sacs and alveoli arise from the alveolar duct. »
Epithelia of lung alveoli. The layer of cells covering the lining of the tiny air sacs at the end of the… »
Round, granular, mononuclear phagocytes found in the alveoli of the lungs. They ingest small inhaled particles resulting in degradation and presentation of… »
A soft tissue tumor that is most common in older children and teenagers. It begins in embryonic muscle cells (cells that develop… »
The thickened bony structures in the mandible and maxilla that contain the sockets of the teeth. »
The terminal dilation of an alveolar duct that gives rise to alveoli in the lung. »
The tissue separating adjacent alveolar air spaces. »
A soft tissue tumor that is most common in older children and teenagers. It begins in the soft supporting tissue that connects… »
The alveolar structure that contains alveolar cells type I and II and macrophages. »
Tiny air sacs at the end of the bronchioles (tiny branches of air tubes) in the lungs. The alveoli are where the… »
Solitary or multiple foci of increased cellularity distal to terminal bronchioles. The background of broncho-alveolar architecture remains detectable, and epithelial cells… »
Surgical preparation of the alveolar ridges, commonly used for the reception of dentures. »
Any of the terminal sacs in the lungs through which gas exchange takes place with the pulmonary capillary blood. »
An analogue of the antineoplastic benzoquinone antibiotic geldanamycin. Alvespimycin binds to HSP90, a chaperone protein that aids in the assembly, maturation and… »
The hydrochloride salt of alvespimycin, an analogue of the antineoplastic benzoquinone antibiotic geldanamycin. Alvespimycin binds to HSP90, a chaperone protein that aids… »
The white myelinated fibers in the hippocampus adjacent to the wall of the lateral ventricle. »
A synthetic trans-3,4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity. Alvimopan is a selective and competitive antagonist at mu-opioid receptors,… »
The Alvin J Siteman Cancer Center is dedicated to advancing new approaches to cancer prevention, diagnosis, and treatment through research. It became… »
A substance being studied in the treatment of several types of cancer. It stops cells from dividing and may kill cancer… »
A synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent… »
A subjective answer indicating a strong preference for number explanations over word explanations. »
A subjective answer indicating a strong preference for word explanations over number explanations. »
A question about whether an individual is or was always trying to improve their physical appearance. »
Human ALX4 wild-type allele is located in the vicinity of 11p11.2 and is approximately 50 kb in length. This allele, which encodes… »
A brain disorder that usually starts in late middle age or old age and gets worse over time. Symptoms include loss of… »
A brain disorder that usually starts in late middle age or old age and gets worse over time. Symptoms include loss of… »
Caring for someone who has Alzheimer's disease (AD) can be stressful and overwhelming. It's important to take care of yourself. Ask for… »
A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to… »
The CDISC version of the Alzheimer's Disease Assessment Scale-Cognitive (CDISC ADAS-Cog) containing 15 summary-level tests. This version is based on combining the… »
A standardized questionnaire developed by Galasko et al in 1997 as part of the Alzheimer's disease cooperative study, which is used to… »
A standardized questionnaire developed by Galasko et al in 1997 as part of the Alzheimer's disease cooperative study, which is used to… »
A standardized questionnaire developed by Galasko et al in 1997 as part of the Alzheimer's disease cooperative study, which is used to… »
A standardized rating scale developed by Lon S. Schneider in 1997 to evaluate a clinically relevant change in an individual's Alzheimer's Disease… »
The Alzheimer's Disease Neuroimaging Initiative's (ADNI) version of the Auditory Verbal Learning Test (AVLT Version A). This version is modified from… »
Cyclin-dependent kinase 5 (cdk5), a multi-functional kinase, and its neuron-specific activator p35 are required for neurite outgrowth and cortical lamination. Proteolytic… »
Alzheimer's disease (AD) is a chronic disorder that slowly destroys neurons and causes serious cognitive disability. AD is associated with senile plaques… »
This gene plays a role in the formation of cholic acid in peroxisomes. »
Human AMACR wild-type allele is located within 5p13.2-q11.1 and is approximately 21 kb in length. This allele, which encodes alpha-methylacyl-CoA racemase protein,… »
A retinal neuron that lacks large axons, having only processes that resemble dendrites. »
A type of poisonous mushroom that has harmful effects on the kidneys and liver. It is responsible for most fatal cases of… »
A type of poisonous mushroom that has harmful effects on the kidneys and liver. It is responsible for most fatal cases of… »
A triazine-based diuretic agent. Amanozine is structurally similar to the diuretic agent chlorazanil. »
A synthetic tricyclic amine with antiviral, antiparkinsonian, and antihyperalgesic activities. Amantadine appears to exert its antiviral effect against the influenza A virus… »
A drug used to treat infections caused by the influenza A virus. It blocks the ability of the virus to infect cells… »
The sulfate salt of amantadine, a synthetic tricyclic amine with antiviral, antiparkinsonian, and antihyperalgesic activities. Amantadine appears to exert its antiviral effect… »
A chimeric IgG1 monoclonal antibody against human mesothelin with potential anti-tumor activity. Amatuximab specifically targets mesothelin, a cell surface glycoprotein involved in… »
Transient loss of vision in one eye due to retinal ischemia. »
An arbitrary unit for the measurement of Amb a 1 (or Antigen E), a 38 kD glycoprotein that is the major allergen… »
A tripeptidic nitrogen mustard compound and bifunctional alkylating agent with antineoplastic activity. »
An antiseptic agent with potential antibacterial and antileukemic activity. Although the exact mechanism of action remains to be fully elucidated, ambazone appears… »
A bisquaternary ammonium alcohol with parasympathomimetic activity. The positive charge of ambenonium allows it to act as an acetylcholinesterase inhibitor by binding… »
The chloride salt form of ambenonium, a quaternary ammonium compound with parasympathomimetic activity. Ambenonium chloride is a rapid indirect-acting cholinergic agonist that… »
The tetrahydrate and chloride salt form of ambenonium, a bisquaternary ammonium alcohol with parasympathomimetic activity. The positive charge of ambenonium allows it… »
A drug used to treat insomnia (inability to sleep), and anxiety. It is a type of imidazopyridine (sedative hypnotic). Also called… »
In or of the immediately surrounding area; relating to the immediate surroundings of something. »
An expansion of the subarachnoid space extending forward between the corpus callosum and the thalamus; it encloses the internal cerebral veins. … »
Sample is stored at ambient conditions and not tested immediately. »
Issue associated with any undesired acoustic energy or vibration that tends to interfere with the operation of the device. »
Issue associated with compromised device-performance at the ambient room temperature. »
A rare congenital abnormality in which the infant's external genitalia do not have the typical appearance of a male's or female's… »
The oil extracted from the seeds of Abelmoschus moschatus. Ambrette seed oil is used for aches and stiffness and for its aromatic… »
A natural polyketide isolated from the myxobacteria Sorangium cellulosum with antifungal activity. Ambruticin interferes with the osmoregulatory system by activating fungal high… »
Those facilities which administer health services to individuals who do not require hospitalization or institutionalization. »
Nursing care provided in an ambulatory setting, such as a clinic or physician's office. »
A facility which primary purpose is to provide elective surgical care, in which the patient is admitted to and discharged from within… »
A publicly or privately owned institution which is primarily established and licensed for the purpose of providing elective surgical treatment of outpatients… »
A surgical procedure performed on an outpatient basis. It may be hospital-based or performed in an office or surgicenter. »
A benzenesulfonamide-based diuretic. Ambuside is structurally similar to thiazide type diuretics and acts in a similar manner. »
A synthetic glucocorticoid receptor agonist that mimics the metabolic, anti-inflammatory, and immunosuppressive activity of the natural glucocorticoids. Amcinonide interacts with specific corticosteroid… »
A condition in which there is a slow breakdown of cells in the center of the retina (the light-sensitive layers of nerve… »
A drug used before autologous stem cell transplantation in patients with non-Hodgkin lymphoma or multiple myeloma. AMD 3100 is given together with… »
Human AMD1 wild-type allele is located in the vicinity of 6q21 and is approximately 21 kb in length. This allele, which encodes… »
A semisynthetic, broad spectrum beta-lactam penicillin with antibacterial activity. Amdinocillin specifically binds to and inactivates penicillin-binding protein 2 (PBP 2) located on… »
The pivoxil ester form of a semisynthetic, broad spectrum beta-lactam penicillin with antibacterial activity. Amdinocillin specifically binds to and inactivates penicillin-binding protein… »
A parasitic infectious disorder caused by amoebas. The parasite may cause colitis which is manifested with bloody diarrheas, abdominal pain, nausea and… »
Dysentery resulting from ulcerative inflammation of the bowel, caused chiefly by infection with ENTAMOEBA HISTOLYTICA. This condition may be associated with amebic… »
A non-neoplastic, congenital or non-congenital disorder charcaterized by marked reduction or absence of megakaryocytes and thrombocytopenia. »
A type of skin cancer in which the cells do not make the pigment melanin. Skin lesions are often irregular and may… »
Cylindrical epithelial cells in the innermost layer of the enamel organ. Their functions include contribution to the development of the dentinoenamel junction… »
A rare, cytologically malignant ameloblastoma that may metastasize. »
A rare, aggressive malignant tumor that originates from an odontogenic cyst in the maxillomandibular region. It combines the histologic features of… »
A rare, aggressive odontogenic malignant tumor that arises usually from the mandible and less frequently from the maxilla. It combines the… »
A very rare ameloblastic carcinoma that originates from a pre-existing benign ameloblastoma. »
A very rare ameloblastic carcinoma that originates from a pre-existing intraosseous benign ameloblastoma. »
A very rare ameloblastic carcinoma that originates from a pre-existing extraosseous benign ameloblastoma. »
A rare benign neoplasm arising from tooth-forming tissues. It is characterized by the presence of a fibromyxoid stroma, epithelial component, dentin, and… »
A rare neoplasm arising from tooth-forming tissues. It usually arises from the posterior mandible. It is characterized by the presence of an… »
A rare neoplasm arising from tooth-forming tissues. It usually arises from the posterior mandible. It is characterized by the presence of an… »
A locally aggressive malignant neoplasm arising from odontogenic tissue. It occurs in the mandible and less often in the maxilla. It… »
The most common odontogenic tumor, arising from the epithelial component of the embryonic tooth and usually affecting the molar-ramus region of the… »
A novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2. Amenamenir stabilizes the interaction… »
Indicates the person or authoritative body who made an amendment. »
A change in a document made by correction, adding, substituting or omitting a certain part. Amendments are the mechanism of changes introduction,… »
A document, memo or brief that enumerates the differences between two versions of a study protocol document. »
A submission that contains additional supportive material to augment information previously submitted. Examples include responses to information requests, additional draft labeling during… »
Association of dental professionals specializing in the prevention, diagnosis and treatment of diseases affecting the gums and supporting structures of the teeth… »
The world's largest general non-profit scientific society. It fulfills its mission to 'advance science and serve society' through initiatives in science policy;… »
Facilitates communication and dissemination of knowledge among scientists and others dedicated to the cancer problem through presentations and discussions of new and… »
The American Brain Tumor Association (ABTA) is a not-profit independent global organization that funds brain tumor research and provides the information patients… »
A nationwide, community-based voluntary health organization, the largest private source of cancer research funds in the U.S. Headquartered in Atlanta, Georgia, the… »
The American Cocker Spaniel has very long hanging ears, a rounded head, and a profuse, feathered, medium-length coat. The body is compact,… »
A classification system for coronary stenosis based upon characteristics that influence the difficulty of percutaneous coronary revascularization. »
Discrete (less than 10 mm length) and concentric and readily accessible and non-angulated segment less than 45 degrees and smooth contour and… »
Tubular (10-20 mm length) or eccentric or moderate tortuosity of proximal segment or moderately angulated segment, 45-90 degrees or irregular contour or… »
Diffuse (length greater than 2cm) or excessive tortuosity of proximal segment or extremely angulated segments greater than 90 degrees or total occlusions… »
A national medical society for obstetricians and gynecologists. »
A non-profit association for cancer care administrators in the US. The College focuses on providing educational, funding, peer resources/networking support and… »
A national medical society for internal medicine professionals. It publishes 'Annals of Internal Medicine'. »
A professional society of physicians who limit their practice to radiation oncology, physicians currently enrolled in a fellowship program and radiation oncology… »
An FDA-designated accrediting body that includes radiologists, radiation oncologists and medical physicists. The ACR focuses its activity on making imaging safe, effective… »
An infrastructure for multi-institutional clinical trials of imaging and related disciplines applied to cancer. The group has been in operation since March… »
Standard criteria to compare the effectiveness of various arthritis medications or treatments. The American College of Rheumatology criteria consists of a variety… »
Standard criteria to compare the effectiveness of medications or treatments for rheumatoid diseases. The American College of Rheumatology criteria consists of a… »
A scientific and educational association of surgeons with the main goal to improve the quality of care for the surgical patient by… »
A cooperative group sponsored by the NCI whose primary goal is to evaluate surgical therapies in the management of patients with malignant… »
The most common form of leishmaniasis that is transmitted through the bite of female phlebotomine sand flies or after exposure to leishmania… »
A professional association of dentists, committed to advancing the public's oral health, the ethical and scientific advancement of the field, and the… »
A nonprofit health organization providing diabetes research, information and advocacy. The mission of the Association is to prevent and cure diabetes and… »
The American Eskimo is a white Spitz-type dog. It has a wedge-shaped head with muzzle and skull about the same length. It… »
The American Foxhound is a large hound with broad, pendant ears and a short, hard coat. It is taller than most… »
The aromatic root of the perennial herb Panax quinquefolius, native to eastern North America. American ginseng, used in Chinese traditional medicine and… »
Denotes a person having origins in one of the indigenous peoples of North America, who lived on the continent prior to the… »
A person having origins in any of the original peoples of North and South America (including Central America) and who maintains tribal… »
A group formed for the purpose of developing a system of clinical staging for cancer that is acceptable to the American medical… »
The American Lung Association is a voluntary national health organization funded by contributions from the public, along with gifts and grants from… »
A voluntary membership organization of physicians that sets standards for the profession of medicine, and is highly focused on medical education. Publishes… »
The oldest and largest organization of public health professionals in the world, representing more than 50,000 members from more than 50 occupations… »
A group of islands in the South Pacific Ocean, between Hawaii and New Zealand and east of Samoa. »
An educational, research and scientific association of physicians organized to raise and maintain the standards of the medical practice of anesthesiology and… »
The world's leading professional organization representing physicians of all oncology disciplines and subspecialties. ASCO sets the standard for cancer care, supports funding… »
The world's largest professional society concerned with the causes and treatment of blood disorders. Its mission is to further the understanding, diagnosis,… »
The American Staffordshire is a very muscular, stocky dog. It has a broad, powerful head, short muzzle, and very strong jaws. The… »
A tobacco control trial conducted over the 7-year period from 1991-1998. It focused on helping smokers who want to quit, protecting nonsmokers… »
A questionnaire designed to help men determine how bothersome their benign prostatic hyperplasia urinary symptoms are and to determine how effective their… »
The American Water Spaniel is an active, muscular and hardy dog with a broad skull. It has a crisp-textured, tightly curled or… »
A man-made radioactive element with atomic symbol Am, atomic number 95, and atomic weight 243. »
An in vivo assay test used to determine if an agent, such as a chemical, is capable of causing mutations in living… »
A topoisomerase II inhibitor of the anthrapyrazole family that causes covalent cross-links in DNA of tumor cells. »
Acetate salt of Ametantrone, a topoisomerase II inhibitor of the anthrapyrazole family that causes covalent cross-links in DNA. »
A drug used to treat some types of cancer, rheumatoid arthritis, and severe skin conditions, such as psoriasis. Amethopterin stops cells from… »
An optical condition in the eye where there is an error of refraction of light rays on the retina. »
A drug that is used to treat certain skin conditions and is being studied in the treatment of cutaneous (skin-related) T-cell cancer… »
Human AMFR wild-type allele is located within 16q21 and is approximately 64 kb in length. This allele, which encodes autocrine motility factor… »
A substance being studied in the treatment of cancer. It binds to a protein called hepatocyte growth factor (HGF), which may cause… »
A drug used to prevent or treat certain bone problems. Under the brand name Xgeva, it is used to prevent broken bones… »
A drug used to treat patients with immune thrombocytopenic purpura (ITP) who do not get better with other forms of treatment. In… »
A substance that is being studied in the treatment of some types of cancer. It belongs to the families of drugs called… »
A hormone made by the ovaries in females and the testicles in males. AMH helps to form the male and female reproductive… »
Human AMH wild-type allele is located in the vicinity of 19p13.3 and is approximately 3 kb in length. This allele, which encodes… »
This gene plays a role in gonadal development. »
Human AMHR2 wild-type allele is located within 12q13 and is approximately 8 kb in length. This allele, which encodes anti-Muellerian hormone type-2… »
One of 800 terephthalanilides synthesized and tested preclinically in the late 1950's and early 1960's. Chosen in the 1990's for further… »
Amidophosphoribosyltransferase (517 aa, ~57 kDa) is encoded by the human PPAT gene. This protein is involved in purine biosynthesis. »
Any substance that inhibits amidophosphoribosyltransferase, an enzyme that catalyzes the commiting step on de novo purine synthesis. Inhibition of amidophosphoribosyltransferase inhibits DNA… »
An organic compound derived from pyridine with potassium channel inhibition activity. Amifampridine inhibits potassium channel efflux, increasing the duration of the action… »
A drug used as a chemoprotective drug to control some of the side effects of chemotherapy and radiation therapy. »
A phosphorylated aminosulfhydryl compound with cytoprotective activity. Amifostine is dephosphorylated by alkaline phosphatase to an active free sulfhydryl (thiol) metabolite in the… »
An antibiotic drug used to treat infection. It belongs to the family of drugs called aminoglycoside antibiotics. »
The sulfate salt of amikacin, a broad-spectrum semi-synthetic aminoglycoside antibiotic, derived from kanamycin with antimicrobial property. Amikacin irreversibly binds to the bacterial… »
A synthetic microsphere formulation with arterial occlusive properties. Amilomer, a product produced by partially hydrolyzing starch and epichlorohydrin, contains degradable starch microspheres… »
A synthetic pyrazine derivative with antikaliuretic and diuretic properties. Amiloride inhibits sodium channels located in the distal tubules and collecting ducts of… »
The hydrochloride salt of amiloride, a synthetic pyrazine derivative with antikaliuretic and diuretic properties. Amiloride inhibits sodium channels located in the distal… »
A class of organic compounds that contain nitrogen as the pivotal atom for functional groups. There are several different types of amines… »
The univalent hydrocarbon radical -NH2. »
One of several molecules that join together to form proteins. There are 20 common amino acids found in proteins. »
Amino Acid Biosynthesis consists of cellular enzymatic reactions that produce amino acids, organic compounds containing an amino and a carboxyl group and… »
Any derivatives of amino acids that containing amino (-NH2) and carboxyl (-COOH) groups. »
A type of nutritional support consisting of a mixture of various animo acids in solution. »
The measurement of the amount of amino acids in a biologic specimen. »
An inherited disorder that affects the metabolism of the amino acids. Representative examples include alkaptonuria, homocystinuria, tyrosinemia, and phenylketonuria. »
The determination of the ratio of one amino acid compared to another amino acid present in a sample. The measurement may be… »
A process that involves the binding of any member of the group of amino acid neurotransmitters, including glutamate, aspartate, serine, glycine and… »
The arrangement of amino acids in a protein. Proteins can be made from 20 different kinds of amino acids, and the structure… »
Amino Acid Synthesis Inhibition involves interference with, or restraint of, enzymatic formation of organic compounds that contain an amino (-NH2) and a… »
Amino Acid Transporter proteins carry organic compounds containing an amino (-NH2) and a carboxyl (-COOH) group through solubility barriers, such as aqueous… »
Amino acids and chains of amino acids connected by peptide linkages. »
