Library / English Dictionary

    MELANIN

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    Insoluble pigments that account for the color of e.g. skin and scales and feathersplay

    Classified under:

    Nouns denoting substances

    Hypernyms ("melanin" is a kind of...):

    animal pigment (pigment occurring in animals)

    Holonyms ("melanin" is a substance of...):

    feather; plumage; plume (the light horny waterproof structure forming the external covering of birds)

    cutis; skin; tegument (a natural protective body covering and site of the sense of touch)

    Derivation:

    melanize (make or become black)

    melanize (convert into, or infiltrate with melanin)

    Credits

     Context examples: 

    The pars compacta nerve cells contain melanin and are involved in motor control.

    (Pars Compacta, NCI Thesaurus)

    A benign nevus characterized by the absence of melanin pigment in the melanocytes.

    (Nonpigmented Nevus, NCI Thesaurus)

    TYRP2 and TYRP1, melanosomal membrane glycoproteins upregulated in melanoma cells, are involved in melanin synthesis.

    (Murine TYRP2 Plasmid DNA Vaccine, NCI Thesaurus)

    This protein may play a role in melanin production.

    (Melanoma Antigen Recognized by T-Cells 1, NCI Thesaurus)

    This allele, which encodes melanoma antigen recognized by T-cells 1 protein, may be involved in the regulation of melanin biosynthesis.

    (MLANA wt Allele, NCI Thesaurus)

    This gene is involved in melanin biosynthesis.

    (DCT Gene, NCI Thesaurus)

    In vivo, tyrosine plays a role in protein synthesis and serves as a precursor for the synthesis of catecholamines, thyroxine, and melanin.

    (L-Tyrosine, NCI Thesaurus)

    Mimicking the action of a-MSH, afamelanotide stimulates melanocytes to increase the production and release of melanin.

    (Afamelanotide, NCI Thesaurus)

    A type of skin cancer in which the cells do not make the pigment melanin.

    (Amelanotic melanoma, NCI Dictionary)

    A monoclonal antibody (MoAb) against extracellular melanin with tumor targeting activity.

    (Anti-Melanin Monoclonal Antibody PTI-6D2, NCI Thesaurus)


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