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METAPHASE
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I. (noun)
Sense 1
Meaning:
The second stage of mitosis
Classified under:
Nouns denoting natural processes
Hypernyms ("metaphase" is a kind of...):
phase of cell division (a stage in meiosis or mitosis)
Holonyms ("metaphase" is a part of...):
mitosis (cell division in which the nucleus divides into nuclei containing the same number of chromosomes)
Sense 2
Meaning:
The second stage of meiosis
Classified under:
Nouns denoting natural processes
Hypernyms ("metaphase" is a kind of...):
phase of cell division (a stage in meiosis or mitosis)
Holonyms ("metaphase" is a part of...):
meiosis; miosis; reduction division ((genetics) cell division that produces reproductive cells in sexually reproducing organisms; the nucleus divides into four nuclei each containing half the chromosome number (leading to gametes in animals and spores in plants))
Context examples:
FJ5002 inhibits telomerase by interfering with holoenzyme assembly and telomere interaction, thus leading to replication-dependent shortening of telomeres with a concurrent increase in aneuploid metaphases and apoptotic cells.
(FJ5002, NCI Thesaurus)
A process of progressive and tight packing of dispersed replicated interphase chromatin into compact structures in metaphase prior to mitotic or meiotic nuclear division or during apoptosis in eukaryotic cells.
(Chromosome Condensation, NCI Thesaurus)
Expressed most in prophase through metaphase, during maximal microtubule assembly from centrosomes, by human TUBG1 Gene (Tubulin Family), ubiquitous and highly conserved 451-aa 51-kDa Gamma Tubulin 1 is a component of microtubule organizing centers such as spindle poles or pericentriolar microtubule-nucleating material of centrosomes that interacts with GCP2 and GCP3 and may be involved in minus-end nucleation of microtubule assembly.
(Gamma Tubulin 1, NCI Thesaurus)
The chromosome characteristics of an individual or a cell line are usually presented as a systematized array of metaphase chromosomes from a photomicrograph of a single cell nucleus arranged in pairs in descending order of size and according to the position of the centromere.
(Karyotyping, NLM, Medical Subject Headings)
A cell division process consisting of a complex series of events or phases (prophase, prometaphase, metaphase, anaphase, telophase) by means of which two daughter nuclei normally receive identical complements of the chromosomes and DNA content characteristic of the original somatic cells of the species.
(Nuclear Division, NCI Thesaurus)
