Health / Medical Topics |
MRE11A wt Allele
Human MRE11A wild-type allele is located in the vicinity of 11q21 and is approximately 77 kb in length. This allele, which encodes double-strand break repair protein MRE11A, is involved in the modulation of DNA recombination, telomere maintenance and double-strand break repair. Mutation of the gene is associated with ataxia telangiectasia-like disorder. (NCI Thesaurus)
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This gene plays a role in DNA recombination and repair.
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The MRE11/RAD50 double-strand break repair complex consists of 5 proteins: Nibrin, p200, p400, MRE11, and RAD50. This complex possesses manganese-dependent single-stranded DNA…
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Human MRC2 wild-type allele is located in the vicinity of 17q23.2 and is approximately 66 kb in length. This allele, which encodes…
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This gene is involved in extracellular matrix remodeling.
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Human MRC1 wild-type allele is located in the vicinity of 10p12.33 and is approximately 102 kb in length. This allele, which encodes…
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This gene is involved in endocytosis of glycoproteins by macrophages.
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