mTORC2

A protein complex that is involved in the both serine/threonine phosphorylation and the regulation of protein synthesis in response to cellular…

An active metabolite of NV-128, a novel flavonoid small molecule inhibitor of the mammalian Target of Rapamycin (mTOR), with potential antineoplastic…

Human MTOR wild-type allele is located in the vicinity of 1p36.2 and is approximately 156 kb in length. This allele, which encodes…

mTOR (mammalian target of rapamycin) appears to play a central role in signaling caused by nutrients and mitogens such as growth factors…

An orally bioavailable mammalian target of rapamycin (mTOR) kinase inhibitor with potential antineoplastic activity. mTOR kinase inhibitor OSI-027 binds to and inhibits…

An orally available inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. mTOR kinase inhibitor CC-223 inhibits the activity…