Health / Medical Topics |
Murine MCA Ricin Conjugate
An immunotoxin consisting of a murine monoclonal antibody (MCA) conjugated to the toxin ricin. The monoclonal antibody component binds to cell surface antigens, thereby targeting delivery of cytotoxic ricin to a specific cell type. The ricin component binds to cells and disrupts ribosomal activity and protein synthesis and induces cell cycle arrest. (NCI Thesaurus)
YOU MAY ALSO LIKE
A honeycombed section of bone located near the base of the skull, protruding behind the outer ear. It is connected to…
A cell originating from or isolated from an animal of class Mammalia.
The male reproductive organs. They are divided into the external organs (penis, scrotum, and urethra) and the internal organs (testis, epididymis, ductus…
Cytolytic lymphocytes with the unique capacity of killing natural killer (NK)-resistant fresh tumor cells. They are interleukin-2-activated NK cells that have no…
Lymphocytes that show specificity for autologous tumor cells. Ex vivo isolation and culturing of TIL with interleukin-2, followed by reinfusion into the…
White blood cells formed in the body's lymphoid tissue. The nucleus is round or ovoid with coarse, irregularly clumped chromatin while the…