| Health / Medical Topics |
Mutant p53 Peptide Pulsed Dendritic Cell Vaccine
A cancer vaccine consisting of autologous dendritic cells which have been pulsed with a mutant p53 peptide. Vaccination with mutant p53 peptide pulsed dendritic cells may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing mutant p53, resulting in tumor cell lysis. Many tumor cells overexpress mutant p53 proteins, resulting in the loss of apoptosis regulation and abnormal cell proliferation. (NCI Thesaurus)
YOU MAY ALSO LIKE
An altered form of an individual, organism, population, or genetic character that differs from the corresponding wild type due to one or…
A drug used to treat advanced cancer of the stomach and pancreas that has not gotten better with other treatment. It is…
Production of genetic alterations by any technique, including chemicals, radiation, recombination, or other molecular biology methods.
Anything that causes a mutation (a change in the DNA of a cell). DNA changes caused by mutagens may harm cells and…
A drug used to treat non-Hodgkin lymphoma, advanced Hodgkin lymphoma, chronic leukemia, mycosis fungoides, and a type of lung cancer called bronchogenic…
Taxonomic family which includes the Ferret.
