Health / Medical Topics |
MUTYH-Associate Polyposis
An autosomal recessive hereditary neoplastic syndrome caused by mutations in the MUTYH gene on chromosome 1p34.1. It is characterized by the presence of multiple colorectal polyps that may progress to carcinoma. Development of gastric and small intestinal polyps may also occur. (NCI Thesaurus)
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Human MUTYH allele is located within 1p34.3-p32.1 and is approximately 92 kb in length. This allele, which encodes A/G-specific adenine DNA glycosylase…
A molecular genetic abnormality that refers to the mutation of the MUTYH gene on chromosome 1p34.1.
This gene plays a role in the repair of oxidative DNA damage.
Characterized or delimited reciprocally, in a mutual or shared manner.
Expresses the extent to which the observed frequency of co-occurrence differs from that expected under the null hypothesis.
Referring to anything in which both parties have reciprocal rights, understanding or agreement.