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Myeloid Dysplasia of Mouse
Comment: Intended to encompass diseases more closely related to human myelodysplastic syndromes than to human myelodysplastic/myeloproliferative or myeloproliferative diseases; Disorder is not a non-lymphoid leukemia; In the peripheral blood mice exhibit: A. Neutropenia (+/- anemia, +/- thrombocytopenia) or B. Thrombocytopenia without either leukocytosis or erythrocytosis or C. Anemia without either leukocytosis or thrombocytosis; Mice exhibit a defect in maturation of non-lymphoid hematopoietic cells as evidenced by any combination of: A. Dysgranulopoiesis, dyserythropoiesis, and/or dysplastic megakaryocytes or B. greater or equal to 20% non-lymphoid immature forms/blasts in bone marrow and/or spleen (NCI Thesaurus/MMHCC)
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The biological process that refers to the maturation of myelocytes.
Any apoptotic process occurring in a neutrophil, eosinophil or basophil.
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Cells which include the monocytes and the granulocytes.
