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MYELOMA
Pronunciation (US): | (GB): |
I. (noun)
Sense 1
Meaning:
A tumor of the bone marrow (usually malignant) composed of cells normally found in bone marrow
Classified under:
Nouns denoting stable states of affairs
Hypernyms ("myeloma" is a kind of...):
malignant neoplasm; malignant tumor; metastatic tumor (a tumor that is malignant and tends to spread to other parts of the body)
Hyponyms (each of the following is a kind of "myeloma"):
multiple myeloma (myeloma that develops in several places at the same time)
Context examples:
In time, myeloma cells collect in the bone marrow and in the solid parts of bones.
(Multiple Myeloma, NIH: National Cancer Institute)
Alteration in the expression of this gene is associated with development of multiple myeloma and infection with Primate Foamy Virus Type 1.
(MIR32 wt Allele, NCI Thesaurus)
This gene is involved in the regulation of gene expression and plays a role in the development of plasma cell myeloma.
(MIR32 Gene, NCI Thesaurus)
This gene is involved in the regulation of gene expression and plays a role in the development of hepatocellular carcinoma, plasma cell myeloma and medulloblastoma.
(MIR19B1 Gene, NCI Thesaurus)
Alteration in the expression of this gene is associated with the development of cancers of the liver and stomach as well as multiple myeloma.
(MIR25 wt Allele, NCI Thesaurus)
A substance being studied in the treatment of certain multiple myelomas and other advanced cancers.
(Atiprimod, NCI Dictionary)
Increased serum concentrations of these peptides are associated with pathologies that cause bone lysis, such as multiple myeloma, osteolytic metastases, and rheumatoid arthritis.
(C-Terminal Telopeptide Type I Collagen, NCI Thesaurus)
DKK1, overexpressed by myeloma cells, is an inhibitor of the WNT signaling pathway and prevents the mediated formation of bone.
(Anti-DKK-1 Monoclonal Antibody LY2812176, NCI Thesaurus)
An allogeneic tumor cell vaccine containing myeloma cancer cells transfected with the granulocyte macrophage-colony-stimulating factor (GM-CSF) gene with potential antineoplastic activity.
(Allogeneic GM-CSF-Based Myeloma Cell Vaccine, NCI Thesaurus)
A substance that is being studied in the treatment of some types of cancer, including pancreatic, lung, breast, prostate, melanoma, and multiple myeloma.
(Amplimexon, NCI Dictionary)