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NECROSIS
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I. (noun)
Sense 1
Meaning:
The localized death of living cells (as from infection or the interruption of blood supply)
Synonyms:
gangrene; mortification; necrosis; sphacelus
Classified under:
Nouns denoting natural phenomena
Hypernyms ("necrosis" is a kind of...):
death (the permanent end of all life functions in an organism or part of an organism)
Hyponyms (each of the following is a kind of "necrosis"):
myonecrosis (localized death of muscle cell fibers)
Derivation:
necrotic (relating to or affected by necrosis)
Context examples:
CD30, a cell surface receptor and a member of the tumor necrosis factor (TNF) receptor superfamily, is overexpressed in hematologic malignancies; CD16A is specifically expressed on the surface of NK cells.
(Anti-CD30/CD16A Monoclonal Antibody AFM13, NCI Thesaurus)
A finding indicating the presence of cellular necrosis in a tissue specimen.
(Necrotic Change, NCI Thesaurus)
Inflammation subsided in the children who had been treated with anti-tumor necrosis factor drugs (TNF inhibitors).
(Researchers discover otulipenia, a new inflammatory disease, NIH)
A rare condition that involves inflammation and necrosis of the walls of the blood vessels; may occur in rheumatoid arthritis.
(Necrotizing Vasculitis, NCI Thesaurus)
A uveal melanoma characterized by the presence of tumor cell necrosis.
(Necrotic Uveal Melanoma, NCI Thesaurus)
It may lead to severe abdominal pain and ischemic necrosis of the intestine.
(Abdominal Aortic Thrombosis, NCI Thesaurus)
Inhibition of these processes results in suppression of the production of proinflammatory cytokines, such as tumor necrosis factor alpha and interleukin 6.
(Acai Berry Juice, NCI Thesaurus)
The disease is a combination of necrosis of the mucosa with inflammation.
(Necrotizing Enteritis of the Mouse Intestinal Tract, NCI Thesaurus/MMHCC)
Similar to astrocytic glial tumors, these higher grade lesions show increased vascularity and tumor necrosis.
(Mouse Anaplastic Oligodendroglioma, NCI Thesaurus/MMHCC)
CD antigen expressed on surface of monocytes, macrophages, eosinophils, neutrophils; lipopolysaccharide receptor; signals production of tumor necrosis factor.
(Monocyte Differentiation Antigen CD14, NIH CRISP Thesaurus)
