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Neuroendocrine Carcinoma
Definition 1
A malignant neuroendocrine neoplasm composed of cells containing secretory granules that stain positive for NSE and chromogranin. The neoplastic cells are often round and form clusters or trabecular sheets. Representative examples are small cell carcinoma, large cell neuroendocrine carcinoma, and Merkel cell carcinoma. (NCI Thesaurus)
Definition 2
A malignant neuroendocrine neoplasm comprising cells containing secretory granules. (NCI Thesaurus/CDISC)
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