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NICOTINIC ACID
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A B vitamin essential for the normal function of the nervous system and the gastrointestinal tract
Synonyms:
Classified under:
Hypernyms ("nicotinic acid" is a kind of...):
B; B-complex vitamin; B complex; B vitamin; vitamin B; vitamin B complex (originally thought to be a single vitamin but now separated into several B vitamins)
Context examples:
Vitamin B3, also called nicotinic acid or niacin, is a precursor to NAD (nicotinamide adenine dinucleotide), which is essential to metabolism and likely very ancient in origin.
(Vitamin B3 might have been made in space, delivered to Earth by meteorites, NASA)
A nicotinic acid derivative.
(Oxiniacic Acid, NCI Thesaurus)
Upon entry, the light chain portion of the toxin is activated and cleaves the protein SNAP-25, thereby preventing the fusion of acetylcholine (ACh)-containing synaptic vesicles with the cell membrane and, so, the release of ACh into the neuromuscular junction; subsequent binding of ACH to motor end-plate nicotinic acid receptors and ACh-mediated muscle contraction are thus blocked.
(botulinum toxin type A, NCI Thesaurus)
Not enough nicotinic acid can cause a disease called pellagra (a condition marked by skin, nerve, and digestive disorders).
(Nicotinic acid, NCI Dictionary)
A long-acting nicotinic acid derivative with antilipidemic activity.
(Glunicate, NCI Thesaurus)
It is always difficult to put a value on the connection between meteorites and the origin of life; for example, earlier work has shown that vitamin B3 could have been produced non-biologically on ancient Earth, but it's possible that an added source of vitamin B3 could have been helpful, said Karen Smith of Pennsylvania State University in University Park, Pa. Vitamin B3, also called nicotinic acid or niacin, is a precursor to NAD (nicotinamide adenine dinucleotide), which is essential to metabolism and likely very ancient in origin.
(Vitamin B3 might have been made in space, delivered to Earth by meteorites, NASA)
A form of nicotinic acid is being studied in the prevention of skin and other types of cancer.
(Nicotinic acid, NCI Dictionary)
Nicotinic acid may help to lower blood cholesterol.
(Nicotinic acid, NCI Dictionary)
Nicotinic acid helps some enzymes work properly and helps skin, nerves, and the digestive tract stay healthy.
(Nicotinic acid, NCI Dictionary)
