Library / English Dictionary

    OSTEOBLAST

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    A cell from which bone developsplay

    Synonyms:

    bone-forming cell; osteoblast

    Classified under:

    Nouns denoting body parts

    Hypernyms ("osteoblast" is a kind of...):

    embryonic cell; formative cell (a cell of an embryo)

    Credits

     Context examples: 

    This gene plays a role in bone formation via regulation of osteoblast differentiation.

    (BMP2 Gene, NCI Thesaurus)

    Osteoblasts and stromal cells may react to bone metastases by producing M-CSF and its osteoclastogenic cofactor RANKL (receptor activator of NF-kappaB ligand).

    (Anti-M-CSF Monoclonal Antibody MCS110, NCI Thesaurus)

    Mature osteoblasts that have become embedded in the bone matrix.

    (Osteocyte, NLM, Medical Subject Headings)

    In addition, fluoride is a mitogen for osteoblasts and stimulates bone formation.

    (Fluoride Ion, NCI Thesaurus)

    The skeleton participates in pH homeostasis as a buffering organ and osteoblasts respond to pH changes in the physiologic range.

    (G Protein-Coupled Receptor 68, NCI Thesaurus)

    This gene plays a role in osteoblast differentiation and ossification.

    (DMP1 Gene, NCI Thesaurus)

    RANK-ligand and osteoprotegerin are produced by osteoblasts and some factors regulate osteoclast activity indirectly through their action on the expression of these factors by osteoblasts.

    (Bone Remodeling Pathway, NCI Thesaurus/BIOCARTA)

    Osteoblasts mineralize bone matrix by promoting hydroxyapatite crystal formation and growth in the interior of membrane-limited matrix vesicles (MVs) and by propagating the crystals onto the collagenous extracellular matrix.

    (Bone Mineralization Regulation Pathway, NCI Thesaurus/BIOCARTA)

    Upon administration of calcium-46 chloride aqueous solution, calcium-46 is preferentially taken up by osteoblasts, which generate mineralized osteoid containing calcium.

    (Calcium-46 Chloride Aqueous Solution, NCI Thesaurus)

    Upon administration of calcium-41 chloride aqueous solution, calcium-41 is preferentially taken up by osteoblasts, which generate mineralized osteoid containing calcium.

    (Calcium-41 Chloride Aqueous Solution, NCI Thesaurus)


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