| Library / English Dictionary |
PATHOGENESIS
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The origination and development of a disease
Classified under:
Nouns denoting natural processes
Hypernyms ("pathogenesis" is a kind of...):
pathologic process; pathological process (an organic process occurring as a consequence of disease)
Hyponyms (each of the following is a kind of "pathogenesis"):
focalisation; focalization (the confinement of an infection to a limited area)
Context examples:
Inactivation of tumor suppressor BCDS2 Protein, encoded by Breast Cancer, Ductal 2 Gene, may represent a fundamental step in the pathogenesis of ductal carcinoma of the breast.
(Breast Cancer Suppressor-2, NCI Thesaurus)
These observations indicate that cleavage of p35 to p25 by calpain may be involved in the pathogenesis of Alzheimer's disease.
(Alzheimer's Disease Pathway BioCarta, NCI Thesaurus/BIOCARTA)
Overexpression of this gene promotes the pathogenesis of B-Cell lymphomas, due to anti-apoptotic activity.
(BCL2 Gene, NCI Thesaurus)
These genes code for the epidermal growth factor receptor (EGFR) family of receptors which is important in the control of normal cell proliferation and in the pathogenesis of human cancer.
(Oncogene ERB B, NLM, Medical Subject Headings)
Mutations or altered expression of these proteins contributes to PD pathogenesis through common mechanisms that result in proteasome dysfunction, mitochondrial impairment, and oxidative stress.
(Parkinson's Disease Pathway KEGG, NCI Thesaurus/KEGG)
These mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression.
(Melanoma Pathway, NCI Thesaurus/KEGG)
A subdiscipline of virology focusing on aspects of human virology that directly pertains to virus-induced clinical conditions, including epidemiology, pathogenesis, diagnosis and detection, and prevention and treatment.
(Clinical Virology, NCI Thesaurus)
Understanding mechanisms that modify H. influenzae signaling will contribute to further understanding the pathogenesis and treatment of ear infections and chronic obstructive pulmonary disease.
(NFKB Activation Pathway, NCI Thesaurus/BIOCARTA)
Mutant merlin proteins alter cell adhesion, causing cells to detach from the substratum, a possible step in the pathogenesis of NF2.
(Merlin, NCI Thesaurus)
A specialty in biology and medicine focusing on aspects of human parasitology that directly pertains to parasite-induced clinical conditions, including epidemiology, pathogenesis, diagnosis and detection, and prevention and treatment.
(Clinical Parasitology, NCI Thesaurus)
