| Library / English Dictionary |
PHARMACOKINETICS
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The study of the action of drugs in the body: method and rate of excretion; duration of effect; etc.
Classified under:
Nouns denoting cognitive processes and contents
Hypernyms ("pharmacokinetics" is a kind of...):
materia medica; pharmacological medicine; pharmacology (the science or study of drugs: their preparation and properties and uses and effects)
Context examples:
A graphical analysis technique based on a two compartment model that uses linear regression to identify and analyze pharmacokinetics problems involving irreversible uptake in one compartment.
(Patlak Plot, NCI Thesaurus)
The Human Pharmacology Study is a clinical study that involves one or more of following activities: assesses tolerance to the agent, defines/describes pharmacokinetics and pharmacodynamics, explores drug metabolism, drugs interactions, and evaluates agent activity.
(Human Pharmacology Study, NCI Thesaurus)
An assay intended to study interindividual variations in DNA sequence related to drug absorption and disposition (pharmacokinetics) or drug action (pharmacodynamics), including polymorphic variation(s) in the genes that encode the functions of transporters, metabolizing enzymes, receptors, and other proteins.
(Pharmacogenetic Test, Food and Drug Administration)
Compared to other radiolabeled RGD-containing peptides, this agent shows increased affinity to alphaVbeta3 integrin, enhanced tumor uptake as well as improved pharmacokinetics. alphaVbeta3 integrin is overexpressed on certain tumor cells and tumor endothelial cells while minimally or not expressed on healthy, normal cells and plays a key role in angiogenesis, tumor proliferation and survival.
(Gallium Ga 68-labeled BNOTA-PRGD2, NCI Thesaurus)
Drug label must include: trademark and category of product, description of product chemical and physical characteristics, clinical pharmacology, pharmacokinetics, data on absorption, distribution, metabolism and excretion, special populations, clinical studies, efficacy and safety data, indications, contraindications, adverse events warnings and precautions including lab tests; potential drug interactions, carcinogens statement, pregnancy category.
(Medical Product Label, NCI Thesaurus)
