Philadelphia chromosome

Pronunciation

Definition 1

An abnormality of chromosome 22 in which part of chromosome 9 is transferred to it. Bone marrow cells that contain the Philadelphia chromosome are often found in chronic myelogenous leukemia and sometimes found in acute lymphocytic leukemia. (NCI Dictionary)

Definition 2

A translocation between chromosomes 9 and 22. It is the hallmark for chronic myelogenous leukemia (CML). (NCI Thesaurus)

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