Health / Medical Topics |
PKI166
A pyrrolo-pyrimidine epidermal growth factor receptor (EGFR) protein kinase inhibitor with anti-tumor activity.PKI-166 reversibly inhibits HER1 and HER2 tyrosine kinases, belong to the epidermal growth factor receptor family, thereby inhibiting tumor growth and metastasis. (NCI Thesaurus)
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It refers to amino acid residues that can be the target for protein kinase C phosphorylation.
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