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Platelet-derived growth factor
Pronunciation
Definition 1
A family of molecules released from platelets (tiny pieces of cells that are found in the blood and that help the blood clot). Forms of platelet-derived growth factor help to heal wounds and to repair damage to blood vessel walls. They also help blood vessels grow. Also called PDGF. (NCI Dictionary)
Definition 2
The major mitogen in serum for growth in culture of cells of connective tissue origin. It consists of 2 different but homologous polypeptides A and B (~30,000 D) linked by disulphide bonds. The B chain is almost identical in sequence to p28sis, the transforming protein of simian sarcoma virus. (NCI Thesaurus)
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