POLE wt Allele

Human POLE wild-type allele is located in the vicinity of 12q24.3 and is approximately 213 kb in length. This allele, which encodes DNA polymerase epsilon catalytic subunit A protein, plays a role in both DNA base-excision repair and DNA replication. Mutation of the gene may be associated with both increased susceptibility to colorectal malignancies and facial dysmorphism, immunodeficiency, livedo, and short stature (FILS) syndrome. (NCI Thesaurus)

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POLE Gene

This gene is involved in both DNA replication and DNA base-excision repair.

POLD3 wt Allele

Human POLD3 wild-type allele is located in the vicinity of 11q14 and is approximately 175 kb in length. This allele, which encodes…

POLD3 Gene

This gene plays a role in the optimization of DNA replication.

POLD1 wt Allele

Human POLD1 wild-type allele is located in the vicinity of 19q13.3 and is approximately 34 kb in length. This allele, which encodes…

POLD1 Gene

This gene is involved in DNA replication and proofreading.

POLB wt Allele

Human POLB wild-type allele is located in the vicinity of 8p11.2 and is approximately 33 kb in length. This allele, which encodes…