| Health / Medical Topics |
Praziquantel
A pyrazinoisoquinoline derivative with anthelminthic property. Praziquantel increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculature through a subsequent increase in levels of calcium in the sarcoplasmic reticulum. In addition, vacuolization of the tegumental syncytium and blebbing results in tegument disintegration, leads to antigen exposure and elicit host defense responses to the worm. The result is the formation of granulomas and phagocytosis. (NCI Thesaurus)
YOU MAY ALSO LIKE
A drug used to lower the amount of cholesterol in the blood and to prevent stroke and heart attack. It is also…
The active ingredient in a drug used to lower the amount of cholesterol in the blood and to prevent stroke and heart…
A drug used to lower the amount of cholesterol in the blood and to prevent stroke and heart attack. It is also…
A novel platelet inhibitor approved for the reduction of thrombotic cardiovascular events in patients with acute coronary syndrome. Prasugrel produces inhibition of…
A synthetic form of dehydroepiandrosterone with potential chemopreventive activity. Produced endogenously, dehydroepiandrosterone (DHEA) is an intermediate in the conversion of cholesterol…
The hydrochloride salt form of pramoxine, a morpholine derivative with local anesthetic property. Pramocaine hydrochloride decreases the permeability of the neuronal membrane…
