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Primary Sclerosing Cholangitis
Definition 1
A chronic, autoimmune inflammatory liver disorder characterized by narrowing and scarring of the lumen of the bile ducts. It is often seen in patients with ulcerative colitis. Signs and symptoms include jaundice, fatigue, and malabsorption. It may lead to cirrhosis and liver failure. (NCI Thesaurus)
Definition 2
Chronic, nonbacterial inflammatory narrowing of the bile ducts. About 50% of the cases are associated with ulcerative colitis. Treatment is to relieve the obstruction by balloon dilatation or surgery. (NLM, Medical Subject Headings)
Definition 3
recurrent or persistant obstructive jaundice, frequently with ulcerative colitis, due to extensive obliterative fibrosis of the bile ducts. (NIH CRISP Thesaurus)
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