Library / English Dictionary

PROLIFERATE

Pronunciation (US):

(GB):

 I. (verb) 

Sense 1

Meaning:

Cause to grow or increase rapidly

Example:

We must not proliferate nuclear arms

Classified under:

Verbs of size, temperature change, intensifying, etc.

Hypernyms (to "proliferate" is one way to...):

manifold; multiply (combine or increase by multiplication)

Verb group:

proliferate (grow rapidly)

Sentence frame:

Something ----s

Derivation:

proliferation (growth by the rapid multiplication of parts)

proliferation (a rapid increase in number (especially a rapid increase in the number of deadly weapons))

Sense 2

Meaning:

Grow rapidly

Example:

Pizza parlors proliferate in this area

Classified under:

Verbs of size, temperature change, intensifying, etc.

Hypernyms (to "proliferate" is one way to...):

grow (become larger, greater, or bigger; expand or gain)

Verb group:

proliferate (cause to grow or increase rapidly)

Sentence frame:

Something ----s

Derivation:

proliferation (growth by the rapid multiplication of parts)

proliferation (a rapid increase in number (especially a rapid increase in the number of deadly weapons))

Credits

 Context examples: 

When pancreatic stellate cells are activated in response to an injury, they proliferate and synthesize large amounts of extracellular matrix.

(Pancreatic Stellate Cell, NCI Thesaurus)

CD74, an integral membrane protein and tumor associated antigen (TAA), is overexpressed in certain cancer cells and promotes survival in rapidly proliferating tumor cells.

(Milatuzumab-Doxorubicin Antibody-Drug Conjugate, NCI Thesaurus)

They generate vast amounts of energy and proliferate rapidly.

(‘Energetic Cancer Cells’ May Be Origin of Cancer Spread, The Titi Tudorancea Bulletin)

The proliferating cell that appears to be responsible for the clinical manifestations is the Langerhans cell.

(Eosinophilic Granuloma, NLM, Medical Subject Headings)

By blocking DNA synthesis and replication, cancer cells are unable to proliferate.

(Mercaptopurine Oral Suspension, NCI Thesaurus)

In addition, splicing inaccuracies or insertion of additional nucleotides at the segment junctions generate further junctional diversity and somatic hypermutation of V regions, as B-lymphocytes proliferate, create better fitting antigen-binding sites.

(Generation of Antibody Diversity, NCI Thesaurus)

Endometrial stromal cells proliferate and respond to the cyclic variations of estrogen and progesterone.

(Endometrial Stromal Cell, NCI Thesaurus)

When stellate cells are activated in response to an injury, they proliferate and synthesize large amounts of extracellular matrix which results in deposition of scar or fibrous tissue.

(Hepatic Stellate Cell, NCI Thesaurus)

Cardiac cells from mice lacking the Hop gene fail to exit the cell cycle in the normal manner, continuing to proliferate past the normal developmental stage.

(HOP Pathway, NCI Thesaurus/BIOCARTA)

When the proliferating cells are immature myeloid cells and myeloblasts, it is called acute myeloid leukemia.

(Myeloid Leukemia, NCI Thesaurus)