| Library / English Dictionary |
PSA
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A protein manufactured exclusively by the prostate gland; PSA is produced for the ejaculate where it liquifies the semen and allows sperm cells to swim freely; elevated levels of PSA in blood serum are associated with benign prostatic hyperplasia and prostate cancer
Synonyms:
prostate specific antigen; PSA
Classified under:
Hypernyms ("PSA" is a kind of...):
protein (any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes)
Context examples:
A rise in the blood level of PSA (prostate-specific antigen) in prostate cancer patients after treatment with surgery or radiation.
(Biochemical recurrence, NCI Dictionary)
Upon subcutaneous vaccination with the adenovirus-PSA prostate cancer vaccine, the adenovirus infects cells and expresses PSA.
(Adenovirus-PSA Prostate Cancer Vaccine, NCI Thesaurus)
The most well-characterized in this regard is the promoter of the PSA (prostate-specific antigen) gene.
(Androgen Response Element, NCI Thesaurus)
Prostate-specific antigen (PSA) level defined according to specific age groups or ranges, which takes into account the natural increase of PSA levels with increased age.
(Age-Adjusted PSA, NCI Thesaurus)
Also called biochemical recurrence and PSA failure.
(Biochemical relapse, NCI Dictionary)
A cancer vaccine consisting of a recombinant modified vaccinia Ankara (MVA) viral vector encoding genes for prostate specific antigen (PSA) and prostate acid phosphatase (PAP) with potential immunostimulatory and antineoplastic activities.
(MVA-PSA/PAP Prostate Cancer Vaccine, NCI Thesaurus)
Examples of cancer screening tests are the mammogram (breast), colonoscopy (colon), Pap smear (cervix), and PSA blood level and digital rectal exam (prostate).
(Disease Screening, NCI Dictionary)
These “biomarker signatures” outperformed the predictive accuracy of the prostate-specific antigen (PSA) protein, which is currently used for making early diagnoses of prostate cancer.
(Biomarker Signatures of Prostate Cancer, NIH)
In addition, MCP decreases prostate specific antigen (PSA) levels and may remove heavy metals.
(Modified Citrus Pectin Supplement, NCI Thesaurus)
Through a mechanism that is reported to be different from other approved AR antagonists, enzalutamide inhibits the activity of prostate cancer cell ARs, which may result in a reduction in prostate cancer cell proliferation and, correspondingly, a reduction in the serum prostate specific antigen (PSA) level.
(Enzalutamide, NCI Thesaurus)
