Scopolamine

A tropane alkaloid derived from plants of the nightshade family (Solanaceae), specifically Hyoscyamus niger and Atropa belladonna, with anticholinergic, antiemetic and antivertigo properties. Structurally similar to acetylcholine, scopolamine antagonizes acetylcholine activity mediated by muscarinic receptors located on structures innervated by postganglionic cholinergic nerves as well as on smooth muscles that respond to acetylcholine but lack cholinergic innervation. The agent is used to cause mydriasis, cycloplegia, to control the secretion of saliva and gastric acid, to slow gut motility, and prevent vomiting. (NCI Thesaurus)

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SCN2A wt Allele

Human SCN2A wild-type allele is located in the vicinity of 2q24.3 and is approximately 153 kb in length. This allele, which encodes…

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This gene is involved in neuronal excitation.

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Human SCN1A wild-type allele is located in the vicinity of 2q24.3 and is approximately 84 kb in length. This allele, which encodes…