SMAD7 wt Allele

Human SMAD7 wild-type allele is located in the vicinity of 18q21.1 and is approximately 31 kb in length. This allele, which encodes mothers against decapentaplegic homolog 7 protein, is involved in the attenuation of tumor growth factor-beta type 1 receptor signal transduction. (NCI Thesaurus)

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SMAD7 Protein

Encoded by MADH7 Gene (SMAD Family) and induced by TGF-beta and IFNG, ubiquitous (lung, vascular endothelium highest) 426-amino acid SMAD7 Protein is…

SMAD7 Gene

This gene plays a role in signal transduction and regulation of transcription.

SMAD6 wt Allele

Human SMAD6 wild-type allele is located within 15q21-q22 and is approximately 80 kb in length. This allele, which encodes mothers against decapentaplegic…

SMAD6 Protein

Encoded by MADH6 Gene (SMAD Family), ubiquitous (predominantly vascular endothelium) SMAD6 Protein Isoforms A (496-aa 53.5-kD) and B (235-aa) act similar to…

SMAD6 Gene

This gene is involved in signal transduction and regulation of transcription. It also plays a role in development.

SMAD4 wt Allele

Human SMAD4 wild-type allele is located in the vicinity of 18q21.1 and is approximately 50 kb in length. This allele, which encodes…